DETROIT (AP) - Guillermo Moscoso's worst inning as a starter led to another loss for the Oakland Athletics.

Moscoso yielded two-run homers by Miguel Cabrera and Carlos Guillen during Detroit's six-run fifth inning, and Oakland lost 8-3 to the Tigers on Tuesday night.

``It is kind of frustrating, because we played very good baseball, and I lost the game in one inning,' Moscoso said. ``It was really just three mistakes, but they did damage on all of them. You can't leave fastballs up when you are trying to get out of a jam.'

Advertisement

Moscoso (3-5) hadn't allowed more than four earned runs in a game this season, his first as a starter. He allowed six in 4 2-3 innings Tuesday.

The Tigers trailed 3-1 before they grabbed control in the fifth.

After Magglio Ordonez brought Detroit to within a run with a sacrifice fly, Cabrera hit his 20th homer of the season, putting the Tigers ahead to stay. Cabrera's drive went an estimated 422 feet to left and gave him 600 career extra-base hits.

Victor Martinez followed with a double, and Jhonny Peralta's RBI single made it 5-3.

Guillen then hit a two-run shot of his own. It was his first homer since Aug. 14 - shortly before his 2010 season ended because of a left knee injury. Guillen didn't return to the lineup until Saturday. He reached base four times Tuesday.

``It stretches out your lineup any time you get another hitter going in there,' Detroit manager Jim Leyland said. ``Especially a switch hitter like Carlos and a proven hitter.'

Detroit's Rick Porcello (9-6) allowed three runs and eight hits in six innings.

Brennan Boesch hit his second double of the game in the sixth, driving in another run to make it 8-3.

The Tigers might have figured this was their night after Martinez showed impressive agility while scoring in the fourth inning.

``Great feet, you know,' Cabrera said. ``He can play soccer.'

Martinez was on first with two out when Guillen hit a hard grounder that handcuffed first baseman Conor Jackson for an error. The ball bounced over into foul territory down the right-field line, and Martinez tried to come all the way around.

David DeJesus' throw was in plenty of time but a bit wide of home to the first-base side. Suzuki caught it and dove back to tag Martinez, but the runner wasn't there yet.

Rather than slide, Martinez sidestepped the plate entirely. When Suzuki, almost on all fours at the plate, reached out again to make the tag, Martinez reached back with his left arm and touched home.

``That was a very acrobatic - I guess, to say the least - slide,' Leyland said. ``But he got in there and he was safe. It was a big play for us.'

Oakland manager Bob Melvin came out and argued the safe call to no avail. It was 1-0 Tigers.

``Martinez started running around, and your instinct is to go after him instead of making him come to you,' Melvin said. ``He went for the tag and Martinez got his hand in.'

Oakland answered back immediately with three runs in the fifth. Ryan Sweeney singled in a run, and Hideki Matsui hit a two-run single.

Oakland third baseman Scott Sizemore left in the fourth after being hit on the left side of his jaw by a pitch. Sizemore was squaring to bunt when he was beaned. X-rays were negative, and he is day to day.

The A's had the bases loaded with nobody out after Sizemore was hit, but they didn't score. DeJesus grounded into a force play at the plate, and Jackson hit into a double play.

NOTES: Guillen's homer was upheld after a review. Replays showed the ball hit a fan above the wall in right-center. ... The Tigers agreed to terms with OF Tyler Collins, a sixth-round draft pick. ... Detroit CF Austin Jackson (sore left wrist) played for the first time since the All-Star break. He had two hits and scored twice. ... Boesch had three hits, as did Oakland's Cliff Pennington.