TORONTO (AP) - Edwin Encarnacion hit a tiebreaking homer in the eighth inning and drove in three runs as the Toronto Blue Jays beat the San Francisco Giants 3-2 Friday night.

Encarnacion homered into the lower deck in left field on left-hander Barry Zito's first pitch of the eighth, snapping a 2-all tie. The homer was his ninth.

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The third-baseman hit a two-run single in the fifth and went 2 for 2 with a walk.

Scott Downs (2-5) worked one inning of relief for the win and Kevin Gregg closed it out in the ninth for his 17th save in 20 chances.

Zito (7-3) allowed three runs and four hits in eight innings for his 11th career complete game and first since 2009. He walked one and struck out five.

Pablo Sandoval drew a bases-loaded walk off Blue Jays right-hander Brandon Morrow to give the Giants a 1-0 lead in the first.

Zito didn't allow a hit through the first four innings, but was tagged for two runs in the fifth. Alex Gonzalez led off with an infield single, Jose Bautista was hit by a pitch and everyone was safe when Sandoval threw late to second on Lyle Overbay's bouncer to third. Encarnacion followed with a two-run single to left.

The Giants promptly tied it in the top of the sixth. Aubrey Huff led off with a double and Juan Uribe was hit by a pitch, but Huff was thrown out at the plate on Pat Burrell's single to right, with both runners advancing on Aaron Hill's relay throw. Sandoval followed with an RBI grounder.

Morrow allowed two runs and five hits in six innings. He walked three and struck out four.

The Giants are 0-4 at American League ballparks this season. They were swept in a three-game series at Oakland from May 21-23.

NOTES: The Blue Jays signed free agent INF Nick Green and optioned INF Mike McCoy to Triple-A Las Vegas. ... Toronto RHP Dustin McGowan, who has not pitched since 2008, will visit Dr. James Andrews next week after feeling sharp pains in his shoulder recently, the latest setback in his comeback attempt from labrum surgery. ... Three Buffalo Bills players, Jarius Byrd, Lee Evans and Kyle Williams, took part in batting practice before the game. The Bills will play in Toronto twice this season, a preseason game against Indianapolis on Aug. 19, and a regular season game against Chicago on Nov. 7.