DENVER (AP) - Dexter Fowler's single with two outs in the 10th inning scored DJ LeMahieu from third base and the Colorado Rockies rallied for an 8-7 win over the San Diego Padres on Sunday.
Fowler finished with four hits and Troy Tulowitzki had two, including his 16th home run. Rockies starter Juan Nicasio retired his first 16 batters.
Nick Hundley, Cameron Maybin and Mark Kotsay homered for the Padres, who missed an opportunity to take three of four in the series after blowing a three-run lead in the ninth.
Three of the games were won in the winning team's last at-bat. Sunday, it was Colorado's turn.
Rex Brothers (2-0) pitched the 10th for the win.
Tyson Ross (0-3) walked Todd Helton to lead off the 10th. Jonathan Herrera singled with one out and LeMahieu, pinch-running for Helton, moved to third on Tyler Colvin's groundout.
Fowler then singled up the middle to give the Rockies their sixth walk-off win this season and second of the series.
Fowler got the game-winning hit after the Rockies rallied against closer Luke Gregerson in the ninth. Colvin's RBI single made it 7-5 and Carlos Gonzalez tied it with a two-out, two-strike double down the right-field line.
Ross came on and retired Nolan Arenado to send the game into extra innings.
Nicasio was untouchable through the first five innings. He struck out seven and had only one three-ball count, to Will Venable in the second inning.
Maybin grounded out to start the sixth before the Padres broke through. Hundley hit a 2-2 slider into the left-field bleachers to end the drama, and the 33,668 fans at Coors Field gave Nicasio an ovation as Hundley circled the bases.
With the perfect game gone, Nicasio appeared to lose his rhythm. The next three batters singled to make it 4-2 before Gonzalez made a running catch of Venable's liner to end the inning.
Edgmer Escalona came on in the seventh and allowed a solo home run to Maybin and a two-run, pinch-hit homer to Kotsay that gave the Padres a 5-4 lead.
They were the first homers of the year for both players.
The Padres scored two more off reliever Matt Belisle in the eighth to make it 7-4.
San Diego starter Clayton Richard had a rough start to his day even before he took the mound.
A few hours before the game, Richard, Hundley and pitching coach Darren Balsley had a closed-door meeting in the clubhouse manager's office to go over the game plan for the afternoon. When they were done, the door was jammed and couldn't be opened.
After clubhouse personnel tried unsuccessfully to unlock the door with several sets of keys, Richard, Hundley and Balsley removed the pins from the hinges and the door was pushed open from the outside.
Things didn't get much better for Richard when he took the mound. He gave up a two-run homer to Tulowitzki in the first inning and two more runs in the third on a groundout by Gonzalez and a triple by Arenado to make it 4-0.
Richard settled down after that, retiring 10 of the last 12 batters he faced. He allowed four runs on eight hits, struck out three and walked one in six innings.
NOTES: San Diego SS Everth Cabrera singled in the sixth to extend his hitting streak to a career-high 10 games. ... Rockies OF Michael Cuddyer was out of the lineup for the third straight game with a strained rib cage muscle. Manager Walt Weiss said Cuddyer has improved since getting injured in the 12th inning Thursday and with a day off Monday thinks there is a chance the veteran will play the opener against Washington on Tuesday. ... San Diego closer Huston Street (left calf strain) will pitch a simulated game Monday. He is eligible to come off the 15-day DL on Friday. ... Colorado RHP Jhoulys Chacin (3-3) will start Tuesday's opener against Washington. ... Padres RHP Jason Marquis (7-2) will pitch Monday's opener of a three-game series against Atlanta.
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