DENVER (AP) - Christian Friedrich followed the blueprint for the Colorado Rockies.

However, the bullpen couldn't finish the job.

Friedrich, working within the 75-pitch limit dictated by Colorado's new four-man rotation, left the game after the fifth inning with a 2-1 lead.

Two pitchers later, the Rockies were on their way to an 8-4 loss to the San Diego Padres.

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``We pitched badly from the sixth inning on,' manager Jim Tracy said. ``It's unfortunate because the job that Christian Friedrich did was just exceptional. He got us exactly where we needed.'

Wilin Rosario homered for the Rockies. Jordan Pacheco had an RBI single and Chris Nelson a run-scoring double in the eighth for Colorado.

Friedrich was efficient in throwing 74 pitches, and his only mistake was Yasmani Grandal's homer in the fourth - the first of his two home runs - that gave the Padres a 1-0 lead.

Friedrich also shook off a line drive that hit him in the left calf on the fifth pitch of the game to allow just one run and five hits and strike out five.

``It's how I'm supposed to pitch. I need to hit the zone, especially with this new pitch count,' he said. ``The slider was working real well and I threw a couple of curveballs when I needed it. I thought I located the fastball down and away for the most part. We had a good plan going in.'

It fell apart in the later innings.

Batting left-handed in the sixth, Grandal, who was called up from Triple-A before the game, hit a two-run shot into the left-field bleachers off Jeremy Guthrie (3-7) for a 3-2 lead.

It was the first time a player has homered from both sides of the plate for his first two major league hits, according to the Padres, with information supplied from Elias Sports Bureau.

Alexi Amarista, who hit a grand slam Thursday in Houston for his first big league homer, also hit two home runs. The first came off Guthrie leading off the seventh.

``One was a strike slider, one was a changeup 8 inches off the plate,' Guthrie said of the two homers he allowed. ``Both in poor locations because they were hit for homers. You make as many quality pitches as you can and give yourself a better chance to succeed.'

The Padres broke it open in the eighth off Adam Ottavino, scoring four times for an 8-2 lead. Cameron Maybin hit an RBI single with two outs and Amarista followed with a three-run homer.

``From the sixth inning on it was a combination of bad pitches and bad choices,' Tracy said. ``That's what took us out of the game.'

Edinson Volquez (5-7) gave up one earned run and three hits in six innings for the Padres.

The Rockies had just two hits through the first five innings but led 2-1. Rosario tied it at 1 when he led off the fifth with his 13th homer of the season. Pinch hitter Eric Young walked and scored when Grandal, the catcher, overthrew Dexter Fowler's sacrifice bunt.

Volquez worked hard to hold the Rockies down, walking six and striking out eight. He escaped two jams by getting Carlos Gonzalez to ground into double plays.

``We didn't do a lot offensively at the beginning part of the game, you have to give credit to Volquez,' Tracy said. ``He had a really good changeup today. He mixed his changeup and curveball very well. Kept us at bay.'

NOTES: Gonzalez singled in the eighth to extend his hitting streak to nine games. ... Rosario is tied for fourth in franchise history for homers by a rookie. ... Rockies RHP Juan Nicasio (left hamstring strain) threw 45 pitches in a simulated game. The team will decide Sunday on the next step in the pitcher's rehab schedule. ... The Padres will send RHP Kip Wells (0-1) to the mound Sunday while the Rockies are expected to recall LHP Drew Pomeranz (0-2) from Triple-A to start for them.