WASHINGTON (AP) - Roy Oswalt was upset. Domonic Brown was stunned. The rest of the Philadelphia Phillies weren't pleased, either.

A day after the Washington Nationals pasted Cliff Lee, Oswalt gave up just two runs, but it was enough for the Phillies to drop their second straight to Washington, 2-1 on Wednesday afternoon.

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In the top of the sixth inning with the Phillies trailing by a run, manager Charlie Manuel decided to hook Oswalt. It was his fourth start after missing three weeks with a back injury, and it was a stifling afternoon with temperatures well into the 90s.

Oswalt's mood wasn't helped when Brown, who hit for him with the bases loaded, hit a sinking line drive to left that Laynce Nix made a diving catch on. In the bottom of the third, Nix hit a home run for the eventual winning run.

Oswalt bristled when Manuel hit for him.

``That's their decision. He's the manager of the team. I don't question too much of that, but that's the first time I've been taken out at 79 pitches,' Oswalt said. ``We'll see how it goes next time.'

Oswalt (3-3) hasn't won since April 21.

Manuel noted the heat and that many of his pitches were borderline.

Brown rarely starts against left-handers - not even against John Lannan - who won for the first time in 14 starts against Philadelphia.

He was sure he had a hit.

``That's a great play, a Gold Glove-type play out there, especially in that situation. How they had me played, I thought it was gonna fall in,' Brown said.

``I was kinda watching Laynce the whole way and he had a good read on it. It was almost like I saw it in slow motion.'

Entering the game, Lannan had an 0-10 record with a 6.44 record against the Phillies.

``I thought we was gonna score some runs on him, if you want to know the truth,' Manuel said.

``We couldn't get to him. In the past, we've kind of always caught up to him and hit him. If you be patient, make him get the ball up and throw strikes - especially on a hot day like today - that's how you get to him.'

The Phillies had just five hits - four against Lannan (3-5) in 5 1-3 - and one against Todd Coffey, Doug Slaten, Tyler Clippard and Drew Storen in the final 3 2-3.

The Nationals scored in the bottom of the first when Roger Bernadina led off with a single. Ian Desmond bunted him to second and he scored on Jayson Werth's one-out single to left.

Philadelphia tied it in the top of the second when Ryan Howard doubled, Ben Francisco drew a walk and, with one out, Carlos Ruiz hit a grounder to third. Alex Cora booted the groundball for an error and Howard came in to score.

In the top of the third, Lannan hit John Mayberry with a pitch. He stole second before Howard's one-out single to short right, where Danny Espinosa had shifted. Mayberry tried to score from second, but Espinosa's throw to the plate was in time for the out.

Nix homered to right center field with two outs in the fourth - his ninth of the season.

Oswalt allowed two runs and six hits in five innings. He walked two, struck out three and also hit a batter.

NOTES: Phillies SS Jimmy Rollins did not start for just the second time this season. He pinch-hit for Wilson Valdez in the sixth. ... For just the sixth time since 1900, Philadelphia was in first place on May 1 and June 1. ... The Phillies are off Thursday and begin a three-game series in Pittsburgh on Friday. ... Philadelphia is 13-5 against left-handed starters. ... Manuel is looking forward to having OF Shane Victorino (hamstring strain) return from the disabled list on Friday. ``That's gonna be good. That's gonna make us better,' Manuel said. ``Offensively, we're gonna get better and of course, he plays an important position in center field.'