CHICAGO (AP) - A day after getting blown out, losing in extra innings was not any easier for the Texas Rangers.

Kevin Youkilis hit a game-ending RBI single in the bottom of the 10th inning and the Chicago White Sox beat the Rangers 5-4 on Wednesday night.

The Rangers lost 19-2 on Tuesday.

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``It's tough when you lose any game, it doesn't matter the score,' Rangers manager Ron Washington said.

In the 10th inning, Alejandro De Aza, who fouled a ball off his right knee during the at-bat, led off the inning with a walk against Rangers reliever Mike Adams (1-3) then stole second.

On the ninth pitch he saw, Youkilis ended the game with an RBI single to score De Aza, prompting the crowd to shout ``Youuuuk!' for the player acquired in a trade from the Red Sox on June 24.

``Youkilis just kept battling and finally he got the best of me,' said Adams, who threw a perfect ninth inning. ``The first inning is the probably the best I felt all season.'

``I was a little jumpy on the slider,' Youkilis said. ``I was out in front of it but I saw it good. The last time I just told myself to stay back a little bit and if there is a fastball throw my hands in as quick as I can. That happened and I got the pitch.'

Josh Hamilton hit his 26th home run for the Rangers, who had won their previous seven series.

Addison Reed (2-1) pitched a scoreless 10th for the White Sox.

The Rangers scored three runs in the first inning off White Sox starter Dylan Axelrod. With two outs, Hamilton and Adrian Beltre hit back-to-back singles. Then Michael Young snapped an 0-for-13 skid with a two-run double and scored on Nelson Cruz's RBI single. Axelrod threw 25 pitches in 97-degree heat in the first inning.

The White Sox came right back and scored four runs to take the lead.

With one out in the second, Alex Rios doubled to right off Rangers starter Scott Feldman. Feldman then hit A.J. Pierzynski with a pitch. Dayan Viciedo followed with an RBI single, then Alexei Ramirez lined a single to right. Right fielder David Murphy's throw short-hopped to catcher Mike Napoli.

Although he was in front of the plate and in position to tag out Pierzynski, Napoli got barreled over by Pierzynski and lost the ball. Gordon Beckham added a two-run double.

``Giving up the four spot right there after we put up three wasn't the ideal situation,' Feldman said. ``I was just kind of leaving the ball up and they put the bat on the ball and found some holes.'

Hamilton's homer tied the game at four and it stayed that way until the 10th.

Axelrod rebounded after a rough first inning to pitch 5 2-3 innings. He allowed four runs and seven hits.

Feldman went six innings and allowed four runs and six hits.

``I wish Feldman hadn't given up four runs in the second inning, but after that he put up four zeroes and gave us a chance,' Washington said.

Before the game, the Rangers announced that Yu Darvish will not make his final scheduled start of the first half as the Rangers attempt to get him some extra rest in his first season in the majors.

Both the team and Darvish said Wednesday there is nothing physically wrong with the 25-year-old right-hander.

Darvish was scheduled to start Friday, but rookie Martin Perez will take his place.

NOTES: Before the game, the White Sox placed right-hander reliever Jesse Crain on the 15-day disabled list with a right shoulder strain, retroactive to June 24. The White Sox recalled RHP Deunte Heath from Triple-A Charlotte to replace Crain. ... Pierzynski caught his 1,500th career game, most among active catchers and 30th in major league history. ... Rangers SS Elvis Andrus made a nice diving stop and threw out Rios at first in the eighth inning. ... Ramirez's dad, Armando threw out the ceremonial first pitch to Alexei. Armando and his wife Edith saw their son Alexei play for the first time in five years, since Alexei left Cuba in 2007 to play for the White Sox.