LOS ANGELES (AP) - Perhaps 49-year-old Jamie Moyer is starting to feel his age.

The Colorado Rockies' left-hander gave up five runs and seven hits over five innings Friday night in a 7-3 loss to the Los Angeles Dodgers. Moyer, who turns 50 in November, is winless in four starts with a 6.43 ERA since breaking former Dodger Jack Quinn's record as the oldest pitcher to win a major league game.

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``It is frustrating, but that's the game of baseball,' the 25-year veteran said. ``It's a pitch here, a pitch there, a hitter here, a hitter there, a base hit ... it can change a game. It can allow a mediocre game to be a mediocre game, a decent game to turn into a poor game or a decent game to turn into a really good game.'

Moyer, who has given up more home runs than any pitcher in history, served up his 517th to the second batter he faced. Mark Ellis drove a 3-2 pitch into the left-field bullpen for his first homer with the Dodgers, who didn't get another baserunner until Andre Ethier doubled with two outs in the fourth and scored on Bobby Abreu's single.

``I faced Ellis a fair amount in the American League, but I hadn't faced him in a long time,' Moyer said. ``Based on the information off him tonight, I wish I'd have pitched him the same way I did when I was in the American League. I made two mistakes and he hit the ball well.'

Moyer (1-3) is 1-4 with a 6.37 ERA in eight career starts at Dodger Stadium. The first time he pitched here, in his fourth big league start, he didn't make it out of the first inning - retiring two of the eight batters he faced in the Chicago Cubs' 11-4 loss to Orel Hershiser on July 10, 1986.

``Our approach against Moyer was just to try to see something over the plate and be aggressive, but not so aggressive on stuff that's falling off the edge of the plate,' Dodgers right fielder Andre Ethier said. ``There's a lot of movement on some of the pitches he's throwing, so you're going to swing and miss sometimes. But you've got to keep taking your hacks and not be discouraged if you're swinging through some of those pitches or even strike out.'

Ethier and Juan Uribe also homered to back Chris Capuano, who won his fourth straight outing as the Dodgers opened a six-game lead over San Francisco in the NL West. Capuano (5-0) equaled the best start of his eight-year career, allowing a run and four hits through seven innings with three strikeouts and no walks.

``Give credit to their left-handed starter. He pitched terrific,' Rockies manager Jim Tracy said. ``As I recall, we put four balls in play hard. That's it. The rest of it was balls off the ends of the bat and fly balls where he got us reaching. He had an excellent changeup.'

Capuano retired 17 of 18 batters during one stretch before Michael Cuddyer hit a two-out solo homer in the seventh on Capuano's 101st pitch to end his scoreless streak at 24 2-3 innings.

Los Angeles increased the margin to 5-0 in the fifth with a two-out, two-run double by Ellis and a run-scoring double by Ethier that followed an intentional walk to Matt Kemp. Ethier and Uribe added solo homers in the seventh and eighth. Ethier's seventh of the season increased his NL-best RBI total to 32.

The Rockies scored two runs in the ninth against Todd Coffey, who wasn't able to finish a mop-up inning after his long sprint from the bullpen and threw 23 pitches before Ronald Belisario got the final out.

Before the game, the Rockies optioned left-hander Drew Pomeranz to Triple-A Colorado Springs and recalled lefty Josh Outman from their Pacific Coast League club. The 23-year-old Pomeranz is 0-2 with a 4.70 ERA in five starts. He came to the Rockies in a July 2011 trade that sent Ubaldo Jimenez to the Cleveland Indians, who selected Pomeranz fifth overall in the 2010 draft.

``This is the right thing to do, because there are a couple of things in relation to Drew's delivery that we need to get cleaned up,' Tracy said. ``I think it's really important, knowing how special this kid is and the potential that he possesses, that we get him right and don't have him in the big leagues just trying to get by - because he's much better than that.'

The Rockies also said right-hander Jeremy Guthrie, sidelined since April 23 because of a shoulder sprain, will be activated from the disabled list Tuesday to start in San Francisco. Tracy said Guthrie came through Thursday's rehab start for Class-A Modesto ``with flying colors.'

NOTES: Ellis hit six home runs for the Rockies in 70 games last year after spending his first eight-plus big league seasons with Oakland. He had a career-high 19 in 2007, the most by an Athletics second baseman. ... Dodgers leadoff hitter Dee Gordon, who wasn't even born when Moyer made his big league debut, was 0 for 3 against him with two strikeouts and a foul pop. ... Todd Helton singled in the second for his 100th career hit at Dodger Stadium.