MILWAUKEE (AP) - Pedro Alvarez hit two home runs, Andrew McCutchen also went deep, and Jeff Locke pitched six shutout innings to lead the Pittsburgh Pirates to a 5-2 win over the Milwaukee Brewers on Saturday.
Neil Walker added a solo home run for the Pirates, who won for a second time in Milwaukee this season, but for only the ninth time since 2007 at Miller Park - against 47 losses.
Locke (5-1) gave up three hits and struck out a season-high seven, to win his fourth straight game. It was the second straight game he didn't give up a run.
Mike Fiers (1-3), starting in place of Kyle Lohse (elbow), lasted four innings, giving up four runs, including three home runs, and five hits.
Carlos Gomez homered twice for Milwaukee.
Milwaukee is 5-17 in May and has not won back-to-back games since April 29-30 at home against Pittsburgh.
The Pirates grabbed a 1-0 lead in the first inning as McCutchen hit his seventh home run. It was McCutchen's fourth home run off Fiers during his career.
Pittsburgh increased its lead to 3-0 in the second inning. After a single by Walker, Alvarez hit his ninth home run to the right field corner.
Walker's second home run of the year to the second deck in right field in the fourth inning increased Pittsburgh's lead to 4-0.
Gomez hit his seventh home run of the year leading off the seventh inning off Pirates reliever Justin Wilson to cut Pittsburgh's lead to 4-1.
Alvarez added his 10th leading off the ninth inning, a towering shot to the top of the second level in right field.
Gomez hit his second home run of the game in the ninth inning to trim the lead to 5-2. It was Gomez's first career multi-home run game.
Notes: Brewers closer Jim Henderson was to see a doctor Saturday and will be out ``a while,'' Brewers manager Ron Roenicke said. Henderson injured his right hamstring Friday while delivering a pitch that led to the second out in the ninth inning. He gave way to Francisco Rodriguez, who earned a save in the Brewers' 2-1 win . Pirates infielder John McDonald, who was put on the 15-day disabled list May 15 with a lower back strain, will begin a minor league rehab assignment Monday at Triple A Indianapolis . Brewers RHP Yovani Gallardo (3-4) will face Pirates LHP Wandy Rodriguez (5-2) in the series finale Sunday.