Houston Astros vs. Los Angeles Angels Picks, Predictions, Odds

The Houston Astros will take on the Los Angeles Angels in their first back-to-back of the season. First pitch is scheduled for 9:38 PM ET at Angel Stadium in Anaheim, California and can be viewed on Apple TV+.  

Score Prediction

Astros 5, Angels 3 

Best Bets

Houston Astros vs. Los Angeles Angels Betting Predictions

Houston enters this season as reigning American League West champions and runner ups of the World Series. The Astros have a very similar team to last season with the exception of shortstop Carlos Correa signing with the Minnesota Twins. There is no question that Houston will miss Correa, but this team still has plenty of talent as they led the MLB in hits and batting average in the 2021 season. Right-handed pitcher Jake Odorizzi is expected to start for the Astros. Odorizzi went 6-7 last season with an ERA of 4.21. 

The Angels hope that this will be the year they can finally compete with the Astros for the AL West. Star Player Mike Trout has been with the team for 11 years and has yet to win a playoff game or make the postseason since 2014. The lineup this season looks promising with Shohei Ohtani leading off, Trout batting second, and Jared Walsh and Anthony Rendon batting in the 3-4 spot.

Both teams should have a bit easier time swinging the bat in this one after the top dogs took the mound opening day. I like the value in the Astros moneyline here. After a tough opening day matchup against Ohtani, the Astros should be a bit more comfortable in the second game with the Angels. 

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Updated on 04/23/2024
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Houston Astros vs. Los Angeles Angels Betting Odds

  • Astros +100
  • Angels -120
  • Astros +1.5 (-189)
  • Angels -1.5 (+155)
  • Over 8.5 (-120)
  • Under 8.5 (+100)

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Los Angeles has lost 11 of its last 16 games. (Getty)

Houston Astros vs. Los Angeles Angels Betting Resources

  • Date: Friday, April 8, 2022
  • Matchup: AL West
  • Stadium: Angel Stadium
  • Location: Anaheim, California
  • TV-Time: Apple TV+ - 9:38 p.m. ET

Houston Astros Betting Analysis

The Astros finished last season with an ATS record of 85-93, going 41-48 at home and 44-45 on the road. Houston has had recent success against LA, going 6-2 in their last eight games when playing on the road against LA. The total went over in 95 of Houston’s 178 games played last season, but went under in five of their last seven postseason games.  

After losing to the Braves in the World Series last season, the Astros have the fourth best odds to win the World Series at +1000. Even with the loss of Carlos Correa the Astros still have their core unit of Jose Altuve, Yuli Gurriel, and Alex Bregman. Gurriel has looked great in spring training, hitting three homeruns and nine RBIs in just 19 at-bats. Houston led the league in scoring per game last season with an average of 5.34 runs per game.  

Jake Odorizzi is expected to get the start on Friday. Odorizzi was 6-7 last season with an ERA of 3.62 and recorded 91 strikeouts in 104.2 innings pitched. The veteran pitcher has not pitched against the Angles since the 2019 season when he allowed 3 runs in 10.1 innings pitched throughout two games.  

Los Angeles Angels Betting Analysis

The Angeles finished last season with an ATS record of 74-88, going 36-45 at home and 38-43 on the road. The Angels struggled at home to end the season with a 2-10 SU home record in their last 12 home games. The total went over in 87 of LA’s 162 games played including five of their last seven home games.  

Los Angeles currently has the 11th best odds to win the World Series at +2500. The Angels have high expectations this year after missing the playoffs this past season despite Shohei Ohtani’s dominant season. Ohtani will be the star of the show again this season, but the question is do they have enough talent around him to take the next step. If Mike Trout can remain healthy and LF Jo Adell can have a breakout season, they should be able to compete with the Astros for the AL West title. The Angels ranked 17th in scoring last season with an average of 4.46 runs per game.  

Key Players to Watch

  • HOU: Yordan Alvarez - DH (Last Game: 1-3, HR, R, RBI, BB)
  • HOU: Alex Bregman - 3B (Last Game: 2-4, HR, R, RBI)
  • LAA: Mike Trout - OF (Last Game: 1-3, BB)
  • LAA: Shohei Ohtani - DH (Last Game: 0-4, K)

Probable Pitchers

  • HOU: Jake Odorizzi - RHP (6-7, 4.21 ERA, 91 K, 1.25 WHIP)
  • LAA: Reid Detmers - LHP (1-3, 7.40 ERA, 19 K, 1.79 WHIP)

Houston Astros vs. Los Angeles Angels Betting Conclusion

I like the Astro’s bats to be the main attraction in this one. With Ohtani not on the mound, the Astros should be able to have plenty of success in their second game of four against the Angels. Backing Houston here at +100.