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Last Updated May 08, 2022, 14:16 PM

St. Louis Cardinals vs. San Francisco Giants Picks, Predictions, Odds

The St. Louis Cardinals (15-10) will take on the San Francisco Giants (14-11) Saturday for game-three of a four-game series. First pitch is scheduled for 7:15 PM ET at Oracle Park in San Francisco, California and can be viewed on FS1.  

Score Prediction

Cardinals 4, Giants 3 

Best Bets 

St. Louis Cardinals vs. San Francisco Giants Betting Predictions

St. Louis is off to a nice start this season and are currently two and a half games behind Milwaukee for first place of the NL Central. The Cardinals have won four of their last five games, including a 7-1-win Thursday night over the Giants in game-one of this series. The offense has been solid this season, but the bullpen has been excellent, holding opponents to two runs or less nine times on the season. The left-hander Steven Matz is scheduled to start on Saturday. Matz is 3-1 in five games this season with an ERA of 4.56 and has allowed 29 hits, 12 earned runs, and struck out 27 batters in 23.2 innings.  

San Francisco is fourth in the NL West and are three-games behind the LA Dodgers for first place. The Giants find themselves in a bit of a slump as of late, losing six of their last seven games prior to their matchup with St. Louis on Friday night. In their last four games, the bullpen has given up 30 runs while the offense has scored only eight. Right-handed pitcher Logan Webb is expected to take the mound on Saturday. Webb is 3-1 in five games this season with an ERA of 3.26 and has given up 33 hits, 11 earned runs, and struck out 20 batters in 30.1 innings of work.  

I like the total to go over in this matchup. Both pitchers have played well this season, but the Giants have been handing out runs like candy recently and the Cardinals have had their bats working the last few games. Not to mention, the total has gone over in six of the last eight meetings between these two teams when playing in San Francisco. Backing the over here.

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St. Louis Cardinals vs. San Francisco Giants Betting Odds

  • Cardinals +135
  • Giants -155
  • Cardinals +1.5 (-160)
  • Giants -1.5 (+140)
  • Over 6.5 (-110)
  • Under 6.5 (-110)

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St. Louis Cardinals vs. San Francisco Giants Betting Resources

  • Date: Saturday, May 7, 2022
  • Matchup: NL Central vs. NL West
  • Stadium: Oracle Park
  • Location: San Francisco, California
  • TV-Time: FS1 - 7:15 p.m. ET

St. Louis Cardinals Betting Analysis

Prior to the results of Friday night’s game, the Cardinals are 15-10 SU, 14-11 ATS, and have an O/U record of 13-11-1. The total has gone over in four of St. Louis’ last five games. Following this trend, the total has gone over in six of their last eight when playing on the road against the Giants. The Cardinals are 4-1 SU in their last five games and 14-6 SU in their last 20 road games.  

St. Louis may not be the highest scoring team in the league, but they have been consistent this season. As a team the Cardinals have a batting average of .238 (13th), on base percentage of .313 (14th), slugging percentage of .364 (20th), and have scored 108 runs (15th). The third baseman Nolan Arenado has been the team’s best hitter with a batting average of .348 (31-89), seven home runs, and 23 RBIs. Left fielder Tyler O’Neil has also been bringing in runs with a batting average of .213 (19-89), two home runs, and 19 RBIs.  

The Cardinals bullpen is pitching very well this season. As a team they are allowing opponents a batting average of .236 (19th), have an ERA of 3.11 (4th), and have given up 78 runs (3rd). The left-hander Steven Matz is scheduled to start on Saturday. Matz is 3-1 in five games this season with an ERA of 4.56 and has allowed 29 hits, 12 earned runs, and struck out 27 batters in 23.2 innings. Matz last pitched against the Giants in 2019 and gave up six hits, two earned runs, and struck out six batters in 6.0 innings of work.

San Francisco Giants Betting Analysis

After 25 games played San Francisco has gone 14-11 SU, 12-13 ATS, and have an O/U record of 12-12-1. The total has gone over in five of the Giant’s last six games. Following this trend, the total has gone over in 12 of their last 18 games against St. Louis. San Francisco is 1-6 SU in their last seven games and 1-5 SU in their last six games against a National League opponent.  

The Giants have not hit the ball well lately, with just three runs scored in their last three games. As a team San Francisco has a batting average of .236 (14th), on base percentage of .312 (16th), slugging percentage of .367 (18th), and have scored 112 runs (12th). The second baseman Wilmer Flores has been productive with a batting average of .279 (24-86), two home runs, 13 RBIs. Left fielder Joc Pederson has been the teams power hitter with a batting average of .295 (18-61), six home runs, and 10 RBIs.  

San Francisco’s bullpen is in a bit of a slump, giving up 47 runs over the past six games. As a team they are allowing opponents a batting average of .247 (24th), have an ERA of 3.48 (9th), and have given up 94 runs (7th). Right-handed pitcher Logan Webb is expected to take the mound on Saturday. Webb is 3-1 in five games this season with an ERA of 3.26 and has given up 33 hits, 11 earned runs, and struck out 20 batters in 30.1 innings of work. Webb pitched in one game against St. Louis last season and gave up five hits, one earned run, and struck out two batters in 4.0 innings.  

Key Players to Watch

  • STL: Nolan Arenado - 3B (Last Game: TBD)
  • STL: Paul Goldschmidt - 1B (Last Game: TBD)
  • SFO: Brandon Crawford - SS (Last Game: TBD)
  • SFO: Mike Yastrzemski - OF (Last Game: TBD)

Probable Pitchers

  • STL: Steven Matz - LHP (3-1, 4.56 ERA, 27 K, 1.44 WHIP)
  • SFO: Logan Webb - RHP (3-1, 3.26 ERA, 20 K, 1.29 WHIP)

St. Louis Cardinals vs. San Francisco Giants Betting Conclusion

The Giants may have the better team on paper, but the Cardinals have been playing much better baseball as of late. I expect the total to go over 6.5 runs in this matchup. The Cardinals have been hitting well and the Giants relief pitchers have posted a 9.45 ERA of the last five games. The winner of this one could go either way, so I’ll stick with the over in this one.  

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