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Last Updated Dec 22, 2021, 15:00 PM

Cleveland Cavaliers vs. Boston Celtics Predictions, Odds, Picks

Dec. 22, 2021
Michael Crosson
VI Betting Expert
VegasInsider.com

Regular-season NBA action will resume on Wednesday night with a compelling Eastern Conference matchup between the Cleveland Cavaliers and Boston Celtics. Coverage begins from TD Garden at 7:30 p.m. ET.

Score Prediction

Celtics 112, Cavaliers 104

Best Bets

Celtics -5.5 (-110) at DraftKings

Cleveland Cavaliers vs. Boston Celtics Predictions

After finishing 13th in the East with a record of 22-50 last year, Cleveland jumped out to a remarkably strong start to the new season, as the Cavaliers opened with a sturdy 7-4 SU and 8-3 ATS run – despite being underdogs in all 11 of those contests.

Cleveland has kept that same momentum rolling through December too, considering the Cavs’ enter Wednesday’s contest sitting in third place in the East with a record of 19-12 – highlighted by double-digit victories in ten of their last 12 games.

On the other hand, Boston stumbled out to a surprisingly slow start to this season, as the Celtics kicked things off with a 7-8 SU and 9-6 ATS aberration, considering Boston was favored in nine of those matchups, lost eight SU – yet picked up nine wins ATS across that stretch. Try to figure out that one.

Boston just can’t seem to find an offensive rhythm as December continues to unfold though, considering the Celtics enter Wednesday’s contest 2-5 SU and ATS across that last seven games – while averaging just 106.3 PPG across that stretch.

I’ll lay the points with the Celtics here, as Cleveland is too far removed from its defensive identity without the collective presence of Evan Mobley, Jarrett Allen, Collin Sexton, and Isaac Okoro – which should enable Boston to bounce back with a solid home victory in this matchup.

Cleveland Cavaliers vs. Boston Celtics Betting Odds

More Odds | Futures Odds

Cleveland Cavaliers vs. Boston Celtics Betting Resources

  • Matchup: Central vs. Atlantic
  • Date: Wednesday, December 22, 2021
  • Venue: TD Garden
  • Location: Boston, Massachusetts
  • TV-Time: NBA League Pass - 7:30 p.m. ET

Cleveland Cavaliers Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 19-12
  • ATS: 24-7
  • O/U: 11-20

After a lousy 22-50 showing last year, Cleveland ended up serving as the big surprise out of the East to start this season, as the Cavaliers opened with a solid 7-4 SU and 8-3 ATS run – despite getting tagged as underdogs in all of those contests.

The Cavs’ are somewhat of a rare commodity in today’s NBA though, considering their key to success is lockdown defense, highlighted by Cleveland’s current 10-2 SU and 12-0 ATS run, which was propelled by surrendering just 97.4 PPG at the defensive end across that stretch.

Three Cavaliers’ starters entered the league’s health and safety protocols over the weekend though, leaving a good chunk of Cleveland’s rotation sidelined for this Wednesday’s affair – which includes Mobley, Allen, Okoro, and a few others.

Boston Celtics Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 15-16
  • ATS: 16-14-1
  • O/U: 13-17-1

After finishing seventh in the East with a record of 36-36 last year, Boston ended up posting another underwhelming start to this season, as the Celtics opened with a pedestrian 7-8 SU run – despite being favored in ten of those matchups.

The cold truth for the Celtics is that they just haven’t shot the ball very well this season, considering Boston ranks just 15th in scoring and 20th offensive efficiency (108.3 PPG, 1.059 OFF) – while also ranking 23rd in both effective field-goal percentage and three-point percentage (51.4% EFG, 33.7% 3FG).

Cleveland Cavaliers vs. Boston Celtics Head-to-Head

The latest meeting between Boston and Cleveland took place a little over a month ago, as these teams split a two-game set in Cleveland back in mid-November – with both matchups staying well under the total at a combined average of 185 PPG.

Key Players to Watch

  • CLE: Darius Garland - SG (19.1 PPG, 3 REB, 7.3 AST)
  • CLE: Lauri Markkanen - PF (13.7 PPG, 5 REB, 1.3 AST)
  • BOS: Jayson Tatum - SF (25.9 PPG, 8.6 REB, 3.7 AST)
  • BOS: Jaylen Brown - SG (21.8 PPG, 5.3 REB, 2.6 AST)

Cleveland Cavaliers vs. Boston Celtics Betting Conclusion

After picking up a sixth straight victory on Sunday night, the Cavaliers enter Wednesday’s contest as narrow road underdogs against the Celtics at TD Garden – which snaps Cleveland’s six-game streak of getting tagged as a favorite.

I’ll lay the points with the Celtics here, as despite Boston’s recent offensive struggles, averaging just 106.3 PPG across the last seven games – Cleveland is far too difficult to trust without Mobley and Allen holding down the fort in the paint.

Cleveland Cavaliers vs. Boston Celtics Betting Trends

  • The Cavaliers are 14-0 ATS in their last 14 games.
  • The Celtics are 2-5 SU in their last seven games.
  • The Celtics are 8-3 SU in their last 11 home games.
  • The total has gone UNDER in five of the last six Cavaliers' games.


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