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Last Updated Mar 24, 2022, 01:50 AM

Philadelphia 76ers vs. Los Angeles Lakers Predictions, Picks, Odds

Nationally televised NBA action will conclude on Wednesday night with a compelling non-conference showdown between the Philadelphia 76ers and Los Angeles Lakers. Coverage begins from Crypto.com Arena at 10:00 p.m. ET on ESPN.

Score Prediction

Sixers 119, Lakers 107

Best Bets

Sixers -7.5 (-110) at BetMGM

Sixers vs. Lakers Predictions

After earning the top spot in the East with a record of 49-23 SU last year, Philadelphia stumbled out to a surprisingly pedestrian start to this season, as the Sixers opened with a lackluster 16-16 SU and 13-18-1 ATS stretch – while averaging just 105.4 OPPG during that timeframe.

Philadelphia has absolutely dominated since the closing days of December though, considering the Sixers boast impressive records of 28-11 SU and 21-17-1 ATS across their last 39 games – while scoring 110.9 OPPG and allowing just 106.4 DPPG across that stretch.

On the other hand, the Lakers also posted a surprisingly slow start to the season, as Los Angeles kicked things off with a lackluster 10-11 SU and 7-14 ATS stretch – which was primarily chalked up to growing pains associated with the offseason acquisition of Russell Westbrook.

The Lakers have maintained a similarly deficient pace since that point though, considering Los Angeles enters Wednesday riding a head-scratching 21-30 SU and 23-28 ATS skid – while scoring just 111.5 OPPG and surrendering 113.9 DPPG across that window.

I’ll back Philadelphia here, as the Sixers are 9-4 SU and 6-6-1 ATS since James Harden’s debut, while generating 112.7 OPPG and allowing just 108.8 DPPG during that timeframe – likely presenting a steep uphill battle for a Lakers squad that’s surrendering 123.7 DPPG across their latest 3-6 SU skid.

Sixers vs. Lakers Betting Odds

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Sixers vs. Lakers Betting Resources

  • Matchup: Atlantic vs. Pacific
  • Date: Wednesday, March 23, 2022
  • Venue: Crypto.com Arena
  • Location: Los Angeles, CA
  • TV-Time: ESPN - 10:00 p.m. ET
  • Injury Report

Philadelphia 76ers Betting Analysis

  • SU: 44-27
  • ATS: 34-35-2
  • O/U: 31-38-2

After finishing first in the East with a record of 49-23 SU last year, the Sixers posted a surprisingly mediocre start to this season, as Philadelphia went just 16-16 SU across their opening 32-game stretch – while averaging just 105.4 OPPG during that span.

However, Joel Embiid single-handedly carried Philadelphia from December through the trade deadline, considering the Sixers enter Wednesday riding a sturdy 28-11 SU and 21-17-1 ATS run, propelled by Embiid averaging 32.6 PPG, 11.5 REB, 4.2 AST, and 1.4 BLK across that stretch.

Fortunately, help has arrived in the form of Harden, as Philadelphia acquired the ten-time All-Star from Brooklyn at the trade deadline, and he’s made an immediate impact, highlighted by the Beard averaging 22.4 PPG and 10.5 AST across the Sixers’ latest 9-4 SU stretch.

Los Angeles Lakers Betting Analysis

  • SU: 31-41
  • ATS: 30-41-1
  • O/U: 41-31-1

Regardless of the situation, sitting below .500 is an undeniable shortcoming for this Lakers squad, but to be fair, they’ve encountered several injury hurdles, so it’s tough to write them off completely, highlighted by LeBron James missing 18 games this season, while Anthony Davis has missed 35, who’s expected to return any day now.

The Lakers can still flip the script and salvage their season; however, they need to get healthy first, and ultimately shoot the ball better, considering L. A. ranks 23rd in offensive efficiency and 12th in scoring (1.065 OE, 111.5 OPPG) – which doesn’t bode well for a squad that also ranks 19th in defensive efficiency (1.090 DE).

The Sixers are 6-1 ATS in their last seven matchups against the Lakers. (AP)

Sixers vs. Lakers Head-to-Head

Philadelphia swept a two-game regular-season set against the Lakers last year, with both matchups staying under the total at an average of 211.5 PPG. However, the most recent meeting between these teams took place back in January of this season, which resulted in another low-scoring victory for the Sixers (105-87, U 215).

Key Players to Watch

  • PHI: Joel Embiid - C (29.8 PPG, 11.3 REB, 4.3 AST)
  • PHI: James Harden - PG (22.5 PPG, 7.8 REB, 10.2 AST)
  • LAL: LeBron James - SF (30 PPG, 8.2 REB, 6.3 AST)
  • LAL: Russell Westbrook - PG (18.1 PPG, 7.5 REB, 7.2 AST)

Sixers vs. Lakers Betting Conclusion

After posting a tough home victory over Miami without Embiid and Harden on Monday night (W, 113-106), the Sixers hit the road for Wednesday’s contest as short favorites over the Lakers at Crypto.com Arena – marking the sixth time L. A. has been an underdog across their last seven games.

I’ll back Philadelphia here, as the Lakers are 4-10 SU and 4-9-1 ATS in their last 14 games, while scoring 113.9 OPPG and allowing 121.3 DPPG during that timeframe – setting the stage for another unfavorable matchup against a Sixers squad that’s surrendering just 108.8 DPPG across their 9-4 SU stretch since the addition of Harden.

Sixers vs. Lakers Betting Trends

  • The Sixers are 10-4 SU in their last 14 games.
  • The Lakers are 4-10 ATS in their last 14 games.
  • The Sixers are 6-1 ATS in their last seven matchups against the Lakers.
  • The total has gone OVER in six of the last eight Lakers' games.
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