Seattle Seahawks vs. Los Angeles Rams Predictions, Odds, Picks

Dec. 21, 2021
Michael Crosson
VI Betting Expert
VegasInsider.com

The 15th week of regular-season NFL action will conclude on Tuesday night with a heavyweight NFC West bout between the Seattle Seahawks and Los Angeles Rams. Coverage begins at 7:00 p.m. ET on FOX.

Score Prediction

Rams 31, Seahawks 24

Best Bet

Over 45 (-110) at WynnBet

Seattle Seahawks vs. Los Angeles Rams Predictions

After winning the NFC West with a record of 12-4 last year, the Seahawks stumbled out to an incredibly disappointing start to the new season, as Seattle kicked things off with a depressing 3-8 SU and 5-6 ATS skid – with four of those SU losses coming in matchups they were favored in.

Seattle has quickly gained steam over the last few weeks though, considering the Seahawks enter Tuesday’s contest following back-to-back victories over the Niners and Texans, with their offense averaging 31.5 PPG on 390 YPG across that window – and the defense surrendering just 18 PPG on 362.5 YPG across that same stretch.

On the other hand, Los Angeles posted an excellent start with new QB Matthew Stafford under center, as the Rams opened with wins in seven of their first eight games – with six of those victories coming by nine points or more.

The Rams have experienced some growing pains across their latest stretch though, considering L. A. dropped three straight games to Titans, Niners, and Packers – before ultimately bouncing back with convincing victories over the Jaguars (W, 37-7) and Cardinals (W, 30-23) in their latest two matchups.

I’ll take the over here, as we should be in for a shootout between a pair of red-hot and well-rested offenses on Tuesday night, with the Seahawks averaging 31.5 PPG on and 390 YPG across their last two games – and the Rams averaging 33.5 PPG on 387 YPG across that same stretch.

Seattle Seahawks vs. Los Angeles Rams Betting Odds

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The Rams enter Tuesday’s contest favored by roughly a touchdown over the visiting Seahawks, which marks the heftiest underdog tag given to Seattle this season.

The total for Tuesday’s affair is stationed near OU 45 at most shops – marking the lowest over-under set for a Rams’ game this year.

Seattle Seahawks vs. Los Angeles Rams Betting Resources

  • Matchup: NFC West
  • Date: Tuesday, December 21, 2021
  • Venue: SoFi Stadium
  • Location: Inglewood, California
  • TV-Time: FOX - 7:00 p.m. ET

Seattle Seahawks Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 5-8
  • ATS: 7-6
  • O/U: 3-9-1
  • ATS - Away: 1-5-1

After posting a somewhat disappointing 2-2 start to the season, Seattle quickly became one of the league’s toughest teams to evaluate, as the Seahawks entered Week 5 as a slim 2.5-point underdog against a red-hot Rams squad – resulting in their third loss of the year, and an injured Russell Wilson.

Wilson has looked noticeably healthier over the last few weeks though, considering the Seahawks’ offense has racked up 31.5 PPG on 390 YPG across their latest two victories.

Los Angeles Rams Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 9-4
  • ATS: 6-7
  • O/U: 7-6
  • ATS - Home: 3-3

When a team makes a dramatic switch at the quarterback position, it typically takes a few weeks for the offense to settle into a rhythm – but that couldn’t be further from the truth for Stafford and the Rams to open this season, as L. A. posted wins in seven of their first eight games, which included tough victories over the Bucs’, Colts, and Seahawks.

Right before their Week 11 bye though, the Rams posted a pair of disappointing performances against the Titans and Niners, as Stafford and company generated just 13 PPG on 312.5 YPG across losses in Weeks 9 and 10.

The Rams’ offense has seemingly ironed things out since then though, considering L. A. has averaged 31.7 PPG on 375.7 YPG across their latest three affairs.


(AP) The total has gone UNDER in four of the last five meetings between the Seahawks and Rams.

Inside the Stats - Seattle Seahawks

  • Record: 5-8
  • Division Standing: 4th - NFC West
  • Points Scored: 272
  • Points Allowed: 262
  • PS/G: 20.9 (21st)
  • PA/G: 20.2 (5th)
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Inside the Stats - Los Angeles Rams

  • Record: 9-4
  • Division Standing: 2nd - NFC West
  • Points Scored: 366
  • Points Allowed: 293
  • PS/G: 28.2 (4th)
  • PA/G: 22.5 (17th)

Key Players to Watch

  • SEA: Russell Wilson - QB (66.6% CMP, 2,302 YDS, 16 TD, 4 INT)
  • SEA: Tyler Lockett - WR (Wk. 14 @ HOU - 5 REC, 142 YDS, TD)
  • LAR: Matthew Stafford - QB (67.3% CMP, 3,898 YDS, 33 TD, 9 INT)
  • LAR: Odell Beckham Jr. - WR (Wk. 14 - 6 REC, 77 YDS, TD)

Seattle Seahawks vs. Los Angeles Rams Betting Conclusion

After posting an impressive road victory over the Cardinals last week (W, 30-23), the Rams will enter Tuesday night’s contest as a 6.5-point home favorite over the visiting Seahawks – marking just the second time Seattle has been an underdog of six points or more this year.

I’ll take the over here, as this matchup just sounds like a recipe for shootout, with the Rams averaging 31.7 points scored and 22 points allowed across their last two games – and the Seahawks averaging 26 points scored and 18 points allowed across that same stretch.

Seattle Seahawks vs. Los Angeles Rams Betting Trends

  • The Seahawks are 1-5 ATS in their last six matchups against the Rams.
  • The total has gone UNDER in eight of the last 11 Seahawks' games.
  • The Rams are 2-5 ATS across the last seven games.
  • The total has gone UNDER in four of the last five meetings between the Seahawks and Rams.

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  • Use our exclusive BetMGM Bonus Code VIBONUS1500 to unlock BetMGM’s welcome offer for new sportsbook users!
  • Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
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