Minnesota Vikings vs. Buffalo Bills Picks, Predictions, Odds

Michael Crosson Sports Betting Expert

4 minute read

Week 10 of the NFL season will resume on Sunday afternoon with a heavyweight non-conference battle between the Minnesota Vikings and Buffalo Bills. Coverage begins from Highmark Stadium in Orchard Park at 1:00 p.m. ET on FOX.

Updated on 04/25/2024

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MINNESOTA VIKINGS vs. BUFFALO BILLS BETTING PREDICTION

We’re past the halfway mark of the 2022 NFL season, and it looks like the Bills have slowly become the new Chiefs, except with a much better defense, which is a scary thought. However, like the Chiefs, this high-powered Buffalo squad has also become prone to head-scratching offensive lapses, as the Bills scored just 18 PPG on 407 YPG in frustrating division losses to the Dolphins and Jets, opposed to racking up 30.7 PPG on 420 YPG across their six victories.

The Vikings, on the other hand, have very quietly strung together the second-best record in the league through the first half of the season, as Minnesota currently boasts a comfortable 3.5-game lead over Green Bay and Chicago in the NFC North standings with a record of 7-1, and their only loss came on the road in Philly against the undefeated Eagles.

However, I’ll back Buffalo to cover here, as the Bills’ defense has been an absolute terror the last two seasons, highlighted by their top-ranked scoring defensive unit from last year holding its opponents to 21 PTS or less in eight straight contests to open this season (14.8 PPG). And I think we’ll see the Bills move the ball with relative ease against a Minnesota defense that’s allowed 22+ PTS in five-of-eight contests so far this year (20.1 PPG).

Score Prediction: Bills 28, Vikings 20
Best Bet: Bills -6.5 (-110)

MINNESOTA VIKINGS vs. BUFFALO BILLS BETTING ODDS

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MINNESOTA VIKINGS vs. BUFFALO BILLS BETTING RESOURCES

Date: Sunday, November 13, 2022
Matchup: NFC North vs. AFC East
Venue: Highmark Stadium
Location: Orchard Park, New York
Time-TV: FOX, 1:00 p.m. ET

MINNESOTA VIKINGS BETTING ANALYSIS

The Vikings are off to a surprisingly dominant start to the season, as Minnesota racked up 24.1 PPG and allowed just 20.1 PPG across a red-hot 7-1 run to kick off the year, which ranks eighth and 12^th in the league respectively.

Minnesota hasn’t exactly faced the most impressive group of opponents, as the Vikings’ wins thus far have come against the Packers, Lions, Saints, Bears, Cardinals, Commanders, and Dolphins (without Tua).

However, to give credit where credit is due, these are all professionals, and posting a 7-1 record in the NFL certainly isn’t an easy feat under any circumstance. I just don’t think Kirk Cousins and co. stack up against two-way juggernauts like Buffalo, but that’s also the case for most squads in the league.

BUFFALO BILLS BETTING ANALYSIS

The Eagles may currently own the best record in the league at 8-0, however, I can assure you, this Buffalo squad fears absolutely nobody, as the Bills’ defense picked up right where it left off last year by allowing 21 PTS or less in eight straight contests to open the season (13.5 PPG), which is an overwhelming amount of support for an offense that ranks third in scoring at an average of 27.5 PPG.

The Bills still have their flaws. They’re currently juggling a handful of health issues, and their rushing attack in virtually nonexistent outside of the quarterback position. Regardless of how you spin it, though, Buffalo still strikes me as one of the most dangerous teams in football, even if Allen isn’t at full strength.

MINNESOTA VIKINGS vs. BUFFALO BILLS BETTING TRENDS

• The total has gone OVER in 11 of Minnesota's last 16 games.
• The Vikings are 6-0 SU in their last six games.
• The Vikings are 2-4 ATS in their last six games against Buffalo.
• The total has gone UNDER in six straight Bills' games.
• The Bills are 4-1 SU in their last five games.
• The Bills are 7-0 SU in their last seven home games.
• The Vikings are 1-4 SU in their last five games against Buffalo.
• The total has gone UNDER in four of Minnesota's last six road games.
• The total has gone UNDER in four of Minnesota's last five road games against Buffalo.

Where to place a bet this NFL Season?

• Use our exclusive BetMGM Bonus Code VIBONUS1500 to unlock BetMGM’s welcome offer for new sportsbook users!
• Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
• Check out the North Carolina Sportsbooks just before they launch legal online sports betting.

Michael Crosson

Michael Crosson began his time at VegasInsider as a freelance NBA writer back in 2019 while he continued to study Psychology and Biology at James Madison University. Following his graduation in 2021, Michael joined the team full-time, and he's been with VI ever since. Michael still writes NBA, NFL, and MLB for VI, as well as gambling industry news. He's also become a crucial part of our editorial production team. More from Michael Crosson