Oregon vs Creighton Prediction | NCAA Tourney Second Round Picks & Odds

The Second Round of NCAA Tourney begins on Saturday afternoon -- and the seventh matchup of the day we'll be breaking down is Oregon vs Creighton, which is scheduled for 9:40 p.m. ET on TBS.

The Ducks are 5-point underdogs on the spread in Saturday's contest; with the game total stationed at over/under 146 at most sportsbooks.

Here's everything you need to know about Oregon vs Creighton -- our expert prediction and betting picks for this Second Round NCAA Tournament matchup on Saturday, March 23.

Oregon vs Creighton Odds

OREGON @ CREIGH Odds

Oregon vs Creighton Picks & Prediction

There is definitely a lot of love for Oregon, who not only captured the Pac-12 championship, but also cruised past South Carolina as an 11th seed in the first round.

Creighton pulled away from Akron in the second half of Thursday's 77-60 win for the program's fourth consecutive first round game in the tournament.

The Bluejays dominate from inside the arc by posting a 60.5% clip on 2-point attempts, which is 3rd in the nation. Oregon ranks 224th in the country in defending 2-pointers by allowing opponents to shoot 51.3%.

Oregon beat a South Carolina team that relies on slowing the pace as Creighton has way more weapons to turn to.

Another key factor is free-throw shooting in this matchup. You can't control how your opponents fare at the charity stripe, but Creighton's foes shot 78.5% from the line, while Oregon converts on nearly 72% of its attempts.

Creighton is looking for its third Sweet 16 appearance in four seasons and the Bluejays should get it here against a tough Ducks' squad.

Pick: Creighton -5 (-110)

Click this link for betting picks and predictions for all 16 Second Round matchups of the NCAA Tourney!

Oregon vs Creighton Game Time & TV Channel

Date: Saturday, March 23
Matchup: Pac-12 vs Big East
Venue: PPG Paints Arena
Location: Pittsburgh, PA
Time-TV: TBS, 9:40 p.m. ET

Oregon vs Creighton Betting Stats

3) Creighton Bluejays
(Big East, At-Large)

  • Futures: +2300
  • Region: +450
  • SU: 23-4
  • ATS: 17-15
  • O/U: 16-16
  • PPG: 80.8
  • OPPG: 69.5

11) Oregon Ducks
(Pac-12, Automatic)

  • Futures: +22000
  • Region: +6000
  • SU: 23-11
  • ATS: 16-18
  • O/U: 20-4
  • PPG: 75.8
  • OPPG: 72.6

March Madness Betting Resources

March Madness Second Round Odds

The NCAA Men's Tournament Second Round will take place on Saturday, March 23 and Sunday, March 24.

Check out the teams, odds, betting stats and much more on each of the four regions below: