SAN FRANCISCO (AP) - Carlos Carrasco might have been able to remain undefeated on the road had a couple of defensive plays gone differently. As it stands, the Cleveland right-hander will take a 91-pitch complete game every time.

Carrasco allowed one earned run and six hits in recording his second career complete game in the Indians' 4-3 loss to the San Francisco Giants on Friday night.

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``I felt good and every pitch was working, especially the fastball,' Carrasco said. ``I haven't changed anything the last four games. It was just one bad inning and there's nothing we can do about that.'

Carrasco (7-4) took his first road loss after going 4-0 in seven previous starts.

``He was phenomenal,' Indians manager Manny Acta said. ``He kept his composure, went after hitters and kept us right there. He's maturing fast as a pitcher.'

Losing the game was the least of Acta's problems. He also lost outfielder Shin-soo Choo to a broken left thumb sustained when he was hit by a pitch from Jonathan Sanchez in the fourth inning and left the game.

``He's going to be out for a while,' Acta said. ``He means so much for us offensively, defensively, running the bases. ... He's an important part of our lineup. It's a big blow.'

Outfielder Travis Buck is headed to San Francisco to take Choo's place on the 25-man roster.

The Giants took advantage of two errors by Cleveland first baseman Carlos Santana to score three unearned runs off Carrasco, who struck out four and did not walk a batter.

``That's the first time I've ever made two errors in one game,' Santana said. ``It was a bad day and I'm coming back tomorrow with more energy and to take a lot of groundballs early.'

Santiago Casilla (1-1) pitched 1 1-3 innings for the win and combined with Jeremy Affeldt, Sergio Romo and Brian Wilson for 4 1-3 hitless innings to complete the two-hitter in the first meeting between the teams since 2008. Wilson pitched the ninth for his 22nd save in 24 chances.

Sanchez walked two of the first three batters he faced before Santana's two-run double to the gap in left-center.

Choo, who had hit safely in 20 of his previous 26 games, was hit on his left thumb with a 2-1 pitch and fell face first to the dirt as a team trainer rushed out to check on him. He was eventually helped to his feet and paused momentarily along the first base line before walking off the field.

Lou Marson walked and Jack Hannahan followed with an RBI single to drive in pinch-runner Shelley Duncan and make it 3-0.

Cleveland managed only one baserunner the rest of the game. Santana walked to lead off the eighth but was picked off.

Andres Torres hit a 3-2 pitch from Carrasco into the stands above the 25-foot brick wall in right field leading off the fourth.

San Francisco then took a 4-3 lead after scoring three times in the sixth with the help of two errors by Santana.

Santana threw wildly to second base on pinch-hitter Nate Schierholtz's grounder, then bobbled Emmanuel Burris' infield dribbler, allowing Chris Stewart to score. Pablo Sandoval added a sacrifice fly and Torres hustled home on Aubrey Huff's deep foul out down the third base line.

NOTES: Torres' home run was only the 14th at home by the Giants this season, tied with the Los Angeles Angels for fewest in the majors. ... Bochy plans to notify Major League Baseball this weekend of his choice to replace Jim Riggleman on the bench for the All-Star game. Riggleman abruptly resigned as manager of the Washington Nationals on Thursday amid a contract dispute with management. ... San Francisco C Eli Whiteside has a tight quad and was given the night off. Whiteside has started 19 games since Buster Posey sustained a season-ending injury on May 25.