NEW YORK (AP) - Francisco Rodriguez hadn't given up a run since April 17. When his streak finally ended Friday night, the New York Mets couldn't recover.

Domonic Brown grounded a tiebreaking single under the glove of first baseman Daniel Murphy in the ninth inning, and the Philadelphia Phillies scored three times off Rodriguez to beat the sinking Mets 6-4.

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``Hey, I'm a human being. It wasn't my day. I've just got to put it behind me and get ready for tomorrow,' Rodriguez said. ``Everything was fine. I was throwing strikes. A couple of groundballs that went through and that one that took a funny hop to Murph. I didn't get it done. That's the bottom line.'

Jimmy Rollins drove in three runs for Philadelphia and Roy Oswalt had an RBI single to go with six effective innings on the mound. With runners at the corners, Ryan Madson got Murphy to ground into a game-ending double play.

``He gave me a sinker, I came off of it, double play. It wasn't a good at-bat,' said Murphy, who sat in front of his locker with his head down for a while after the game.

Brown entered as a pinch-hitter in the eighth and singled to start the tying rally. He stole a base and scored twice, helping the NL East leaders get off to a good start on a nine-game trip.

Philadelphia had dropped its last four road games since a May 13 victory at Atlanta.

``Whenever they put me in, I know what to expect now. That's what was so good about having me up last year,' Brown said. ``I'm just trying to be prepared for every situation.'

Justin Turner had a career-high four hits for the streaky Mets, who have dropped five of six after winning 10 of 14. Still missing injured boppers David Wright and Ike Davis, they tried to mount a rally in the ninth but fell short.

Jose Reyes scored on an error by center fielder Michael Martinez, Philadelphia's third of the game, to make it 6-4. Jason Bay's single put runners at the corners, but Murphy couldn't come through.

Antonio Bastardo (3-0) worked a hitless eighth and Madson, filling in for injured closer Brad Lidge, earned his 10th save in as many chances.

``Get three late like that, that's huge. It gives me or whoever's coming in kind of a breather. Some wiggle room, you know?' Madson said. ``You've got a couple runs to work with, so just get outs. I was trying to get a double play the whole inning, as soon as Reyes got on.'

Mets starter Chris Capuano struck out his first four batters and fanned eight in six strong innings before Turner's RBI double gave New York a 3-2 lead in the seventh. Jason Isringhausen, however, couldn't hold it - the first time he has coughed up a lead this season.

``I had pretty good life on my changeup today and pretty good command. You try not to get too focused on strikeouts. You try to be economical with your pitches,' Capuano said. ``I think it was, physically, as good as I've felt out there, especially after that last start when I felt shaky. It felt good to get out there and get on the attack and get some quick outs.'

Brown opened the eighth with a single and stole second before scoring on Rollins' double.

Carlos Ruiz and pinch-hitter Ross Gload singled with one out in the ninth against Rodriguez (1-1), who began the night with a scoreless streak of 19 2-3 innings - the longest active run in the majors.

Brown hit a grounder that stayed down on Murphy, who might have had a shot at an inning-ending double play. But he started to whirl toward second without the ball and it scooted into right field for an RBI single.

``Frankie pitched well enough to get out of that. I've got to make that play,' Murphy said.

Rollins followed with a sacrifice fly and Placido Polanco added an RBI infield single to make it 6-3. The Mets, who fell to 18-2 when leading after seven innings, had allowed only two runs in the ninth inning all year.

Rodriguez, lifted in the middle of the inning, was booed as he walked off the mound.

``The only thing we found out today is the guys at the end are human beings. They have pitched so well,' Mets manager Terry Collins said. ``I was a little disappointed to hear the reaction. Frankie's only saved 15 in a row and pitched as well as anybody in either league. It was one of those nights.'

Bay was booed after striking out with runners at first and third to end the fifth, dropping him to 2 for 26 with runners in scoring position this season.

New York opened a 10-game homestand, its first at Citi Field since owner Fred Wilpon's critical comments about Wright, Reyes and Carlos Beltran were published.

NOTES: Mets CF Angel Pagan returned to the lineup after missing more than a month with an injury to his rib cage. He had two hits and a stolen base. ... New York 2B Ruben Tejada made two diving plays and drew a walk from Bastardo to cap a 16-pitch tussle. Tejada fell behind 0-2, then fouled off 10 pitches. ... Turner entered in a 2-for-20 slide, but he has 15 RBIs in his last 12 games. ... New York dropped to 17-5 when Reyes scores at least three runs.