PHOENIX (AP) - Arizona right-hander Josh Collmenter was back in form, his pitches working and over-the-top delivery keeping hitters off balance.

He just wasn't good enough to beat Phil Humber and the Chicago White Sox.

Collmenter bounced back from his first shaky outing with a solid one, but was outpitched by Humber in the Diamondbacks' 8-2 loss to the White Sox on Sunday.

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``Josh threw a good game for us,' Diamondbacks manager Kirk Gibson said.

After confusing opponents with his quirky motion his first six starts, the right-hander hit his first big bump the previous start, giving up five runs - one less than the previous 13 appearances combined - in five innings of a 6-5 loss to San Francisco.

Collmenter (4-3) looked good early against the White Sox, holding them hitless until the fourth inning and to one run over the first six innings.

Then he got into a little trouble in the seventh.

Paul Konerko hit a solo homer, his third in three games, and Alex Rios followed with a solo shot two batters later. Collmenter didn't give up anything else, allowing three runs and five hits to go with five strikeouts in seven innings. A much better outing than the previous one, but still with the same result.

``I had good command, back to my normal stuff,' Collmenter said. ``Other than the seventh inning, everything went well. In the seventh, a couple of bad pitches.'

Chicago never gave the Diamondbacks a chance after that.

Humber pitched effectively into the eighth inning and A.J. Pierzynski hit a three-run double in the eighth inning, giving the White Sox their first series win over Arizona and a little momentum headed into a series against the crosstown rival Cubs

``When the games start against the Cubs, it's a different ball game,' White Sox manager Ozzie Guillen said. ``Chicago's looking for this game and obviously the rivalry is there. You've got to step it up a notch because that's as close as you come to the playoffs.'

Konerko hit a solo homer to match Harold Baines for 56th on the career list with 384, Rios hit his sixth of the season and Alexei Ramirez drove in two on a pair of groundouts. Pierzynski capped a five-run eighth inning with his bases-clearing double, sending Humber (7-3) to his fourth straight win and Chicago its first series win over Arizona in three tries.

``We had a lot of guys who contributed today,' said Humber, 5-0 with a 2.81 ERA in his past eight starts. ``It's good getting out of here with a win in the series against a good team.'

The White Sox had a rough 24 hours physically before Sunday's series finale.

Left-hander John Danks took a liner off the head during his start on Saturday, but stayed in the game and checked out OK after a CT scan. He's expected to make his next start, most likely next Saturday with Jake Peavy expected rejoin the rotation.

Guillen also spent some time with medical personnel Sunday morning, rushing to the hospital to pass a kidney stone. Guillen, who also passed a stone in 2004, was back in the dugout about two hours before first pitch.

Humber certainly didn't have any problems.

The right-hander had the Diamondbacks baffled most of the day, staying out of trouble until allowing two runs in the eighth inning on Ryan Roberts' RBI double and Justin Upton's third hit, a run-scoring single to left.

Humber lasted 7 2-3 innings, giving up two runs and seven hits to become the first White Sox pitcher to go at least seven innings in six straight starts since Jon Garland did it seven straight in 2007.

``It's fun to watch him go out there knowing he's going to give you a chance to win the game,' Guillen said

Chicago put it out of reach in the eighth against Esmerling Vasquez and Joe Paterson, the capper Pierzynski's three-run double that made it 8-0.

Notes: John Green, whose 9-year-old daughter was killed in the Tucson shootings in January, attended the game with his son, Dallas. Christina-Taylor Green was among the five people killed in the shooting that also wounded 13, including Rep. Gabrielle Giffords. John Green is a scout for the Los Angeles Dodgers and the son of former big-league manager Dallas Green. ... Muhammad Ali, who lives in the Phoenix area, also attended the game. ... Chicago's Adam Dunn made his first start in right field since July 30, 2009, with Washington.