Last Updated May 05, 2022, 4:27 PM

Miami Heat vs. Philadelphia 76ers Predictions, Picks, Odds

Regular-season NBA action will resume on Monday night with a heavyweight Eastern Conference clash between the Miami Heat and Philadelphia 76ers. Coverage begins from Wells Fargo Center in South Philly at 7:30 p.m. ET.

Score Prediction

Heat 112, Sixers 106

Best Bets

Over 210.5 (-110) at BetMGM

Heat vs. Sixers Predictions

After earning the top spot in the East with a record of 49-23 SU last year, Philadelphia stumbled out to a surprisingly pedestrian start to this season, as the Sixers opened with a lackluster 16-16 SU and 13-18-1 ATS stretch – while averaging just 105.4 OPPG during that span.

The Sixers have absolutely dominated since late December though, considering Philadelphia enters Monday riding an impressive 27-10 SU and 20-16-1 ATS run – while tallying 111.6 OPPG and allowing just 106.8 DPPG across that window.

On the other hand, Miami barreled out to an excellent start to the season, as the Heat kicked things off with a sturdy 11-5 SU and 12-4 ATS stretch – with nine of those SU victories coming by 10+ PTS.

Aside from their brief nine-game December lull though (3-6 SU, 2-7 ATS), Miami has carried that same momentum all the way through March too, considering Miami boasts records of 33-13 SU and 26-19-1 ATS across their last 46 games – while ranking tenth in offensive efficiency and fourth in defensive efficiency during that timeframe (1.095 OE, 1.048 DE).

I’ll back Philly here, as the Sixers are 8-3 SU and 5-5-1 ATS since James Harden’s debut, while scoring 114.9 OPPG and surrendering 110.5 DPPG during that span – likely presenting a difficult road task for a Heat squad that’s averaging just 107.2 OPPG across their latest 1-4 ATS skid.

Heat vs. Sixers Betting Odds

More Odds | Futures Odds

Heat vs. Sixers Betting Resources

  • Matchup: Southeast vs. Atlantic
  • Date: Monday, March 21, 2022
  • Venue: Wells Fargo Center
  • Location: Philadelphia, PA
  • TV-Time: NBA League Pass - 7:30 p.m. ET
  • Injury Report

Miami Heat Betting Analysis

  • SU: 47-24
  • ATS: 40-30-1
  • O/U: 41-30

After last year’s underwhelming 40-32 SU showing, Miami made some aggressive offseason moves in order to better suit needs at the offensive end – primarily highlighted by the acquisition of six-time All-Star Kyle Lowry.

The transition worked seamlessly out of the gate, as Miami kicked things off with an impressive 11-5 SU and 12-4 ATS stretch, with the Heat’s only ATS loses across that span coming in tough matchups against the Lakers, Clippers, Nuggets, and Celtics.

The depth that Miami sacrificed to acquire Lowry was briefly exposed in November though, considering a revolving door of health and safety concerns spiraled Miami into a brief 3-6 SU and 2-7 ATS skid. But depth hasn’t been much of an issue recently, considering Miami enters Monday riding a sturdy 33-13 SU, 26-19-1 ATS run.

Philadelphia 76ers Betting Analysis

  • SU: 43-26
  • ATS: 33-34-2
  • O/U: 30-37-2

After finishing first in the East with a record of 49-23 SU last year, the Sixers posted a surprisingly mediocre start to this season, as Philadelphia went just 16-16 SU across their opening 32-game stretch – while tallying just 105.4 OPPG during that span.

However, Joel Embiid single-handedly carried Philadelphia from late December through the All-Star Break, considering the Sixers enter Monday riding an impressive 27-10 SU stretch, propelled by Embiid averaging 32.6 PPG, 11.5 REB, 4.2 AST, and 1.4 BLK across that window.

Help has arrived in the form of Harden though, as Philadelphia acquired the ten-time All-Star from Brooklyn at the trade deadline, and he’s made an immediate impact, highlighted by the Beard averaging 22.9 PPG and 10.7 AST across the Sixers’ latest 8-3 SU stretch.

The Heat are 1-4 ATS in their last five games. (AP)

Heat vs. Sixers Head-to-Head

Philadelphia won two-of-three regular-season matchups against Miami last year, with both Sixers’ victories soaring over the total at a lofty average of 252 PPG – while Miami’s lone win stayed under with a score of 106-94 (U 218). The Heat are 2-1 SU against Philly this year though, with all three matchups staying under the number at an average of 195 PPG.

Key Players to Watch

  • MIA: Jimmy Butler - SF (21.1 PPG, 6 REB, 5.1 AST)
  • MIA: Tyler Herro - SG (21.1 PPG, 4.8 REB, 3.8 AST)
  • PHI: Joel Embiid - C (30 PPG, 11.3 REB, 4.4 AST)
  • PHI: James Harden - PG (22.6 PPG, 7.8 REB, 10.3 AST)

Heat vs. Sixers Betting Conclusion

After posting back-to-back home wins over the Pistons and Thunder, the Heat hit the road for Monday’s contest as short favorites over the Sixers at Wells Fargo Center – marking just the second time Philadelphia has been an underdog since Harden’s debut.

I’ll back Philly here, as the Heat are 3-2 SU and 1-4 ATS in their last five games, while tallying just 107.2 OPPG and allowing 106.9 DPPG during that span – setting the stage for a tough road matchup against a Sixers squad that’s averaging 114.9 OPPG across their latest 8-3 SU run.

Heat vs. Sixers Betting Trends

  • The Heat are 1-4 ATS in their last five games.
  • The total has gone UNDER in four of the last five matchups between Miami and Philadelphia.
  • The total has gone UNDER in five of the last eight Heat' games.
  • The Sixers are 2-5 ATS in their last seven matchups against Miami.
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