2025 College Football Odds Week 8: Lines, Spreads, Betting Trends on Biggest Games

Patrick Everson Sports Betting Expert

4 minute read

The College Football Odds Week 8 market features a batch of big games, primarily in the SEC.

Georgia vs. Ole Miss and Tennessee vs. Alabama highlight college football Week 8 odds. And a traditional rivalry is on the menu when USC meets Notre Dame.

Here’s everything you need to know about college football odds Week 8: opening lines, spreads and betting trends for the biggest games, as multiple oddsmakers provide insights on Week 8 college football odds and action.

Check back regularly for updates and use our bet365 bonus code to get the most out of your action.

2025 College Football Odds for Week 8

Louisville vs. Miami Odds

• Opening point spread: Miami -13
• Opening moneyline: Miami TBA/Louisville TBA
• Opening total: Over/Under 53.5 points scored
• Time: 4 p.m. ET Friday (ESPN)

OPENING ODDS UPDATE: No. 2 Miami (5-0 SU/4-1 ATS) got a breather with a bye in Week 7. The Hurricanes just completed a three-game Sunshine State sweep, winning and cashing against South Florida, Florida and Florida State.

In Week 6, Miami was a 3.5-point road favorite and beat the Seminoles 28-22.

Louisville (4-1 SU/1-4 ATS) also had a bye, perhaps much needed after its first loss of the season. In Week 6, the Cardinals fell to Virginia 30-27 in overtime as 6.5-point home favorites.

Circa Sports, highly regarded for its opening numbers, made Miami a 13-point favorite in college football Week 8 odds, at approximately 1:30 p.m. ET Sunday. There was no early spread movement, but the total nudged from 53.5 to 54 shortly after opening.

LSU vs. Vanderbilt Odds

• Opening point spread: Pick
• Opening moneyline: LSU TBA/Vanderbilt TBA
• Opening total: Over/Under 47.5 points scored
• Time: Noon ET Saturday (ABC)

OPENING ODDS UPDATE: No. 17 Vanderbilt (5-1 SU/4-2 ATS) is rested after a week off, following a closer-than-the-final-score-indicated loss at Alabama. The Commodores led 7-0 and 14-7, and the game was tied at 14 at halftime.

Vandy was down 23-14 when 'Bama, looking primarily to run out the clock, scored a touchdown, and the Commodores lost 30-14 as 12.5-point underdogs.

No. 10 LSU (5-1 SU/3-3 ATS) rebounded from its lone loss of the season, a Week 5 setback at Ole Miss. Following a bye week, the Tigers topped South Carolina 20-10 as 8.5-point home favorites.

Circa Sports opened this game at pick 'em in its college football odds Week 8 market. The line quickly moved to Vanderbilt -2.5, then went to -1.5/-2, before setting at -1 at 2:30 p.m. ET Sunday. The total climbed from 47.5 to 49.

Ole Miss vs. Georgia Odds

• Opening point spread: Georgia -6
• Opening moneyline: Georgia TBA/Ole Miss TBA
• Opening total: Over/Under 51.5 points scored
• Time: 3:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: No. 5 Ole Miss (6-0 SU/4-2 ATS) dodged a huge upset bid by Washington State in Week 7. The Rebels closed as massive 33.5-point home favorites and squeaked out a 24-21 victory.

No. 9 Georgia (5-1 SU/2-4 ATS) also didn't weren't particularly inspiring in Week 7. The Bulldogs trailed 10-3 at halftime, but shut out Auburn in the second half en route to a 20-10 victory giving 4.5 points on the road.

Circa opened Ole Miss-Georgia at Bulldogs -6 and quickly went to -6.5 just before 2 p.m. ET Sunday. The total was more on the move, jumping from 51.5 to 54 in Week 8 college football odds.

Texas Tech vs. Arizona State Odds

• Opening point spread: Texas Tech -10
• Opening moneyline: Texas TBA/Arizona State TBA
• Opening total: Over/Under 51.5 points scored
• Time: 4 p.m. ET Saturday (FOX)

OPENING ODDS UPDATE: No. 7 Texas Tech (6-0 SU/5-1 ATS) got a challenge from Kansas in the first half, but ran away in the second half. The Red Raiders were up 21-0 early in the second quarter, but led just 21-17 at the half.

But Tech didn't allow another point and rolled 42-17 as 14-point road favorites.

Arizona State (4-2 SU/3-3 ATS) was ranked No. 21 entering Week 7, but didn't have QB Sam Leavitt at Utah, and it showed. The Sun Devils got buried 42-10 as 9.5-point road underdogs.

Texas Tech opened -10 in Circa's college football odds Week 8 market, with a total of 51.5. There was no movement on the spread, but the total dropped to 50 by 2:30 p.m. ET Sunday.

Tennessee vs. Alabama Odds

• Opening point spread: Alabama -8
• Opening moneyline: Alabama TBA/Tennessee TBA
• Opening total: Over/Under 60.5 points scored
• Time: 7:30 p.m. ET Saturday (ABC)

OPENING ODDS UPDATE: No. 6 Alabama (5-1 SU/4-2 ATS) is on a three-game run against Top 20 talent. Coming off wins at Georgia and vs. Vanderbilt, the Crimson Tide went to Missouri as 3.5-point favorites and squeaked out a 27-24 victory.

No. 11 Tennessee (5-1 SU/3-3 ATS) got all it could handle from unranked Arkansas in Week 7. The Vols trailed at multiple junctures, but pulled ahead 34-17 by early in the fourth quarter. Tennessee then held on for a 34-31 victory, failing to cash as 10-point home chalk.

Alabama hit Circa Sports' college football Week 8 odds as 8-point home chalk, with no early movement.

USC vs. Notre Dame Odds

• Opening point spread: Notre Dame -9
• Opening moneyline: Notre Dame TBA/USC TBA
• Opening total: Over/Under 59.5 points scored
• Time: 7:30 p.m. ET Saturday (NBC)

OPENING ODDS UPDATE: No. 13 Notre Dame (4-2 SU/3-3 ATS) aims to keep its name in the College Football Playoff conversation. In Week 7, the Fighting Irish drilled North Carolina State 36-7 giving 24 points at home.

No. 20 USC (5-1 SU/3-3 ATS) has a chance to put together a couple of eye-catching wins. In Week 7, the Trojans thumped Michigan 31-13 as 3-point home favorites.

Circa Sports opened Notre Dame -9 and dropped to -8 within about 30 minutes Sunday. The total, however, climbed from 59.5 to 61.

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson