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USC vs. Notre Dame: Prediction, Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
USC vs. Notre Dame: Prediction, Odds, Best Bet

Image Credit: MICHAEL CLUBB/SOUTH BEND TRIBUNE / USA TODAY NETWORK via Imagn Images

USC @ ND Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
USC Trojans 415 USC
+13.5 -110 +6.5 -110 +6.5 -105 +6.5 -108 +6.5 -110 +5.5 -110 +6.5 -105 +6.5 -110 +6.5 -109 +10.5 -110  
Notre Dame Fighting Irish 416 Notre Dame
-13.5 -110 -6.5 -110 -6.5 -115 -6.5 -112 -6.5 -110 -5.5 -110 -6.5 -125 -6.5 -110 -6.5 -114 -10.5 -110  
Final
USC Trojans 415 USC
o53.5 -110 o30.5 -115 N/A o30.5 -110 o30.5 -115 o30.5 -110 o30.5 -110 o30.5 -115 o30.5 -121 o60.5 -108  
Notre Dame Fighting Irish 416 Notre Dame
u53.5 -110 u30.5 -105 N/A u30.5 -110 u30.5 -105 u30.5 -110 u30.5 -120 u30.5 -105 u30.5 -109 u60.5 -112  
Final
USC Trojans 415 USC
+285 +235 +240 +240 +235 +205 N/A N/A +230 +310  
Notre Dame Fighting Irish 416 Notre Dame
-360 -300 -300 -298 -278 -250 N/A N/A -315 -395  
Final
USC Trojans 415 USC
+13.5 -110 +3.5 -120 +3.5 -118 +2.5 -105 +3.5 -130 +1.5 -116 +2.5 -105 +2.5 -105 +3.5 -129 +10.5 -110  
Notre Dame Fighting Irish 416 Notre Dame
-13.5 -110 -3.5 -110 -3.5 -110 -2.5 -125 -3.5 even -1.5 -108 -2.5 -125 -2.5 -125 -3.5 even -10.5 -110  
Final
USC Trojans 415 USC
o53.5 -110 o13.5 -115 N/A o13.5 -110 o13.5 -105 o13.5 -120 o13.5 -110 o13.5 -110 o13.5 -112 o60.5 -108  
Notre Dame Fighting Irish 416 Notre Dame
u53.5 -110 u13.5 -115 N/A u13.5 -120 u13.5 -125 u13.5 -104 u13.5 -120 u13.5 -120 u13.5 -117 u60.5 -112  
Final
USC Trojans 415 USC
+285 +170 +185 +160 +165 +150 N/A N/A +175 +310  
Notre Dame Fighting Irish 416 Notre Dame
-360 -220 -235 -215 -200 -194 N/A N/A -235 -395  
Final
USC Trojans 415 USC
+13.5 -110 N/A N/A +5.5 -108 +5.5 -110 N/A N/A N/A N/A +10.5 -110  
Notre Dame Fighting Irish 416 Notre Dame
-13.5 -110 N/A N/A -5.5 -112 -5.5 -110 N/A N/A N/A N/A -10.5 -110  
Final
USC Trojans 415 USC
o53.5 -110 N/A N/A o28.5 -105 o27.5 -125 N/A o28.5 -110 N/A N/A o60.5 -108  
Notre Dame Fighting Irish 416 Notre Dame
u53.5 -110 N/A N/A u28.5 -115 u27.5 +105 N/A u28.5 -115 N/A N/A u60.5 -112  
Final
USC Trojans 415 USC
+285 N/A N/A +220 N/A N/A N/A N/A N/A +310  
Notre Dame Fighting Irish 416 Notre Dame
-360 N/A N/A -265 N/A N/A N/A N/A N/A -395  
Final
USC Trojans 415 USC
+13.5 -110 N/A N/A +2.5 even N/A +3.5 -112 +3.5 -125 N/A N/A +10.5 -110  
Notre Dame Fighting Irish 416 Notre Dame
-13.5 -110 N/A N/A -2.5 -130 N/A -3.5 -114 -3.5 even N/A N/A -10.5 -110  
Final
USC Trojans 415 USC
o53.5 -110 o17 -110 N/A o17.5 -105 N/A o13.5 -215 o16.5 -135 N/A N/A o60.5 -108  
Notre Dame Fighting Irish 416 Notre Dame
u53.5 -110 u17 -110 N/A u17.5 -125 N/A u13.5 +158 u16.5 +105 N/A N/A u60.5 -112  
Final
USC Trojans 415 USC
+285 +155 N/A +190 N/A +186 N/A N/A N/A +310  
Notre Dame Fighting Irish 416 Notre Dame
-360 -190 N/A -260 N/A -235 N/A N/A N/A -395  
Final
USC Trojans 415 USC
+13.5 -110 N/A N/A +2.5 -105 N/A +3.5 -128 +2.5 even N/A N/A +10.5 -110  
Notre Dame Fighting Irish 416 Notre Dame
-13.5 -110 N/A N/A -2.5 -125 N/A -3.5 -104 -2.5 -130 N/A N/A -10.5 -110  
Final
USC Trojans 415 USC
o53.5 -110 o13.5 -110 N/A o13.5 -140 N/A o24.5 +162 o13.5 -120 N/A N/A o60.5 -108  
Notre Dame Fighting Irish 416 Notre Dame
u53.5 -110 u13.5 -110 N/A u13.5 +110 N/A u24.5 -215 u13.5 -105 N/A N/A u60.5 -112  
Final
USC Trojans 415 USC
+285 +160 N/A +180 N/A +200 N/A N/A N/A +310  
Notre Dame Fighting Irish 416 Notre Dame
-360 -190 N/A -238 N/A -265 N/A N/A N/A -395  
Final
USC Trojans 415 USC
+13.5 -110 +0.5 -115 N/A +0.5 -110 N/A +1.5 -114 +1.5 -115 N/A N/A +10.5 -110  
Notre Dame Fighting Irish 416 Notre Dame
-13.5 -110 -0.5 -105 N/A -0.5 -120 N/A -1.5 -118 -1.5 -110 N/A N/A -10.5 -110  
Final
USC Trojans 415 USC
o53.5 -110 o14.5 -110 N/A o14.5 -115 N/A o14.5 -100 o14.5 -105 N/A N/A o60.5 -108  
Notre Dame Fighting Irish 416 Notre Dame
u53.5 -110 u14.5 -110 N/A u14.5 -115 N/A u14.5 -124 u14.5 -125 N/A N/A u60.5 -112  
Final
USC Trojans 415 USC
+285 +140 N/A +130 N/A +154 N/A N/A N/A +310  
Notre Dame Fighting Irish 416 Notre Dame
-360 -170 N/A -166 N/A -194 N/A N/A N/A -395  

The USC Trojans will take on the Notre Dame Fighting Irish in this week's college football action. Kickoff is set for 7:30 p.m. EDT at Notre Dame Stadium in South Bend, Ind. The game will be broadcast live on NBC. Here's everything you need to know about USC vs. Notre Dame odds, the latest college football spreads, college football over/unders and more.

The Notre Dame Fighting Irish opened as a -9.5 point favorite over USC. The total is set at over/under 61.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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USC vs. Notre Dame Best Bet

USC has one of the best offenses in college football. They are currently rated #1 in EPA/pass and #4 in EPA/rush. They are top 5 in both early-downs EPA/play and late-down success rate. This offense will be going against a Notre Dame defense that is half as strong as they were last season.

USC also has the #1 rated safety in the country according to PFF, Bishop Fitzgerald. USC's offensive line did not allow a sack against Michigan last week (one of the strongest pass-rush units in the country). I think USC wins this game and knocks Notre Dame out of playoff contention.

USC vs. Notre Dame Best Bet: USC Trojans +9.5 (-105)


PLACE THIS BET INSTANTLY AT HARD ROCK!

(Pick from Dylan Wilkerson)

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What Time is the USC vs. Notre Dame Game?

The Trojans will take on the Fighting Irish at 7:30 PM ET on Saturday, October 18th.

Where is the USC vs. Notre Dame Game Being Played?

This game is going to be played at Notre Dame Stadium in South Bend, Ind.

How Can I Watch The USC vs. Notre Dame Game?

You can watch USC vs. Notre Dame on NBC.

Can USC Beat The Notre Dame Fighting Irish?

Absolutely! USC is an underdog in this game, but anything is possible in college football!

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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