Angels vs. Astros Predictions, Odds, Preview

May 10, 2021
Kevin Rogers
MLB Expert

Los Angeles Angels vs. Houston Astros Predictions

Score Prediction - Astros 7, Angels 5

Los Angeles Angels vs. Houston Astros - Best Bets

The Angels and Astros hook up for their series of the season as Houston and L.A. are both coming off home wins on Sunday.

This looks like a pitcher-by-committee game for the Angels tonight, who have hit the 'over' in nine consecutive series openers.

  • Over 9.5

Los Angeles Angels vs. Houston Astros Game Odds

  • Los Angeles +145
  • Houston -175
  • Los Angeles (+1.5) -130
  • Houston (-1.5) +105
  • Over (9.5) -115
  • Under (9.5) -105

Odds per BetMGM - Subject to Change

The Astros are coming off a home series win as Houston welcomes Los Angeles on Monday. (AP)

Los Angeles Angels vs. Houston Astros - Betting Analysis

  • Venue: Minute Maid Park
  • Location: Houston, Texas
  • TV-Time: ESPN - 8:10 p.m. ET

Los Angeles Angels vs. Houston Astros - Current Form

The Angels currently sit in last place of the American League West with a 15-18 record, while owning a 7-9 road mark.

The Astros have won three of their last four games since a three-game skid to improve to 18-16 on the season and move two games within Oakland for first place in the division.

Los Angeles Angels vs. Houston Astros - Series History

The Astros have captured four of six matchups with the Angels this season, including taking three of four at Minute Maid Park in late April.

Three of those four games in Houston finishing 'over' the total, while four of six contests between these AL West rivals have gone 'over.'

Pitching Matchup

Los Angeles: Junior Guerra (2-1, 4.95 ERA)

Guerra gets the nod tonight, making his first start since 2018 as a member of the Brewers.

The right-hander has made 12 appearances out of the bullpen this season, as he tossed one scoreless inning in Saturday's 14-11 loss to the Dodgers.

Guerra's longest appearance of the season was 3.1 innings back on April 10 against the Blue Jays in 15-1 loss.

Houston: Luis Garcia (0-3, 3.28 ERA)

The right-hander is winless in four starts this season, but his offense hasn't helped much either. In Garcia's last three starts, the Astros have scored 3, 0, and 2 runs, resulting in two 'unders' and a push.

Garcia pitched well in his last appearance by striking out eight batters in 4.2 innings of a 6-3 defeat to the Yankees on May 5 as a +125 underdog.

Trends to Watch

Los Angeles

  • Over 9-0 last nine series openers
  • 4-6 on road vs. AL West


  • Over 6-0-1 last seven games
  • Over 5-2 last seven series openers