2025 ACC Tournament Odds: Duke Favored vs. Louisville In Final

Patrick Everson Sports Betting Expert

1 minute read

ACC Tournament odds are onto the championship game, after a riveting semifinal round. No. 1 Duke is still around – barely – in pursuit of its first conference title since 2019.

Up next on the 2025 ACC Tournament odds board: Duke vs. either No. 2 seed Louisville or No. 3 seed Clemson.

Here's everything you need to know about college basketball odds for the ACC Tournament championship: opening lines, spreads and betting trends. Check back for updates once the quarterfinal matchups are set, and use our BetMGM bonus code to get the most out of your action.

2025 ACC Tournament Odds Championship Game

Louisville vs. Duke

• Opening point spread: Duke -6.5
• Opening moneyline: Duke -285/Louisville +230
• Opening total: Over/Under 143.5 points scored
• Time: 8:30 p.m. ET Saturday (ESPN)

UPDATE 7:45 P.M. ET SATURDAY: With tipoff 45 minutes out, Duke is -6.5 (-105) in BetMGM Nevada's ACC Tournament championship odds. The Blue Devils opened -5.5, got to -6.5 this morning, briefly went to -5.5 (-115) 30 minutes ago, then returned to the current -6.5 (-105).

"It's 1.5/1 tickets and 4/1 money on Louisville. And they're all over Louisville moneyline, 4/1 tickets and 95% of money," BetMGM Nevada's Scott Shelton said.

The total opened at 146.5 and is now 147.5, with tickets 3/1 and practically all the money on the Over.

UPDATE 12:45 A.M. ET SATURDAY: Duke (30-3 SU/21-12 ATS) was without star freshman Cooper Flagg (ankle) for Friday's quarterfinal against archrival North Carolina. For a while, it looked like Flagg's absence would hardly matter.

The Blue Devils pounded away in the first half, taking a 45-24 lead into the locker room. With nine minutes remaining, Duke still led 63-46. But it all fell apart from there. The Blue Devils narrowly hung on for a 74-71 victory as 6.5-point favorites.

No. 2 seed Louisville (27-6 SU/20-13 ATS) mimicked Duke by letting a big lead slip away against No. 3 seed Clemson. The Cardinals were up 69-54 with just 3:28 remaining, yet nearly got forced to overtime.

Louisville escaped with a 76-73 win catching 2.5 points. The Cards are on an 11-game win streak (7-4 ATS) and are 21-1 SU in their last 22 outings (15-7 ATS).

Big East Tournament odds for the championship game literally just hit the board at DraftKings Sportsbook. So there's nothing to report yet on action. Check back Saturday for updates.

Duke remains the favorite in ACC Tournament futures odds.

ACC Tournament Winner Odds

DraftKings Sportsbook's final teams in the ACC Tournament odds futures book:

• Duke -285
• Louisville +230

Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson