Denver Broncos vs. Los Angeles Chargers Week 3 Prediction: Odds, Best Bet

Denver Broncos vs. Los Angeles Chargers Week 3 Prediction: Odds, Best Bet

Denver Broncos vs. Los Angeles Chargers Odds, NFL Week 3

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DEN @ LAC Odds

The Broncos will take on the Chargers in this week's NFL action. Kickoff is set for 4:05 p.m. EDT at SoFi Stadium in Inglewood, Calif. The game will be broadcast live on CBS. Here's everything you need to know about Broncos vs. Chargers odds, the latest NFL spreads, NFL over/unders and more.

The Chargers opened as a -2.5 point favorite over Broncos. The total is set at over/under 45.5 total points scored by both teams combined.

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Updated on 9/18/25

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Denver Broncos vs. Los Angeles Chargers Best Bet

Herbert is off to an excellent this start this season, largely due to an adjustment in offensive mindset for the Chargers. They lead the league in pass rate over expectation through 2 games and are 5th in neutral pass rate. The ground-and-pound nature of this team under Jim Harbaugh and Greg Roman has given way to an aerial attack.

The increase in passing plays has boosted Herbert's production on the ground. He's posted 16 carries for 63 yards. After recording 7+ carries in just 2 games last season, he's done it in both games to begin this season. Herbert averaged 1.8 scrambles per game last season. He's up to 3.5 per game so far this season. Herbert has 30+ rushing yards in each game.

Denver has played man coverage at the 2nd-highest rate this season. They were 5th last season. Man coverage typically leads to more scramble opportunities, as the defensive backs are focused on their assignments and not looking at the quarterback.

Denver Broncos vs. Los Angeles Chargers Best Bet: Justin Herbert o21.5 Rushing Yards (-110)

(Pick via Derek Carty)


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What Time is the Denver Broncos vs. Los Angeles Chargers Game?

The Denver Broncos vs. Los Angeles Chargers play at 1:00 ET on Sunday, September 21st.

Where is the Denver Broncos vs. Los Angeles Chargers Game Being Played?

This game is going to be played at Raymond James Stadium in Tampa, FL.

How Can I Watch the Denver Broncos vs. Los Angeles Chargers?

You can watch Denver Broncos vs. Los Angeles Chargers on FOX.

Can The Broncos Beat The Chargers?

The Broncos are 2.5 points underdogs vs. the Chargers. Anything can happen in the NFL!