Chargers vs. Raiders Week 2 Prediction: Monday Night Football Odds, Best Bet

Chargers vs. Raiders Week 2 Prediction: Monday Night Football Odds, Best Bet

Los Angeles Chargers vs. Las Vegas Raiders Odds, NFL Week 2

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LAC @ LV Odds

The Chargers will take on the Raiders in this week's NFL action. Kickoff is set for 10:00 p.m. EDT at Allegiant Stadium in Las Vegas, Nev. The game will be broadcast live on ESPN. Here's everything you need to know about Chargers vs. Raiders odds, the latest NFL spreads, NFL over/unders and more.

The Chargers opened as a -3.5 point favorite over Raiders. The total is set at over/under 46.5 total points scored by both teams combined.

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Updated on 9/12/25

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Los Angeles Chargers vs. Las Vegas Raiders Best Bet

I saw all I needed to see from the Chargers in Week 1 to put them in the elite tier of the NFL. Instead of leaning on the run, they finally let Justin Herbert cook against what should be one of the better defenses in the league (the Chiefs). The preseason talk from head coach Jim Harbaugh about his love for Herbert seems to be coming to fruition. The Chargers look like they might have one of the best WR rooms in the league to pair with an incoming breakout season for Herbert. It looks very clear that this offense is going to move the ball at will, and they should flirt with being the top unit in the league if healthy.

The Raiders have to travel across the country for Week 1 and then all they way back, and even though this game is on Monday night, the Chargers will have a significant 2-day rest advantage. Unless the Raiders go into New England and blow out the Patriots, these odds should approach the 200s, so I am just trying to read the tea leaves a little early and jump on a team that looks to have entered into the elite tier and is no longer that Chargers team of the past. It doesn't hurt that we get to free roll any injuries from the Raiders either, as it seems the Chargers emerged from Week 1 healthy.

Los Angeles Chargers vs. Las Vegas Raiders Best Bet: Los Angeles Chargers Moneyline (-172)

(Pick via Brit Devine)


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What Time is the Los Angeles Chargers vs. Las Vegas Raiders Game?

The Los Angeles Chargers will take on the Las Vegas Raiders at 10:00 PM ET on Monday, September 15th.

Where is the Los Angeles Chargers vs. Las Vegas Raiders Game Being Played?

This game is going to be played at Allegiant Stadium in Las Vegas, NV.

How Can I Watch the Los Angeles Chargers vs. Las Vegas Raiders?

You can watch The Raiders vs. The Chargers on ESPN.

Can The Raiders Beat The Chargers?

While it is possible that the Raiders could beat the Chargers, our expert had picks the Chargers to win this Monday Night showdown!