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Featured Last Updated Sep 5 2025, 1:38 PM

NFL: Dolphins vs. Colts, Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
NFL: Dolphins vs. Colts, Prediction, Odds, Best Bet

Image Credit: Mykal McEldowney/USA Today Network via Imagn Images

MIA @ IND Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Miami Dolphins 457 Dolphins
+1.5 -112 +0.5 -125 + +0.5 -125 + +0.5 -125 + +0.5 -125 + -0.5 +110 + +1.5 -125 + -0.5 +105 +1.5 -143 + +1.5 -143 +1.5 -118  
Indianapolis Colts 458 Colts
-1.5 -108 -0.5 +105 + -0.5 +105 + -0.5 +105 + -0.5 +105 + +0.5 -140 + -1.5 +105 + +0.5 -130 -1.5 +116 + -1.5 +117 -1.5 -102  
Miami Dolphins 457 Dolphins
o45.5 -110 N/A N/A N/A N/A N/A N/A o10.5 -115 N/A N/A o47.5 even  
Indianapolis Colts 458 Colts
u45.5 -110 N/A N/A N/A N/A N/A N/A u10.5 -115 N/A N/A u47.5 -120  
Miami Dolphins 457 Dolphins
even -110 + -105 + -108 + -110 + -115 + +104 + -110 -109 + -109 -108  
Indianapolis Colts 458 Colts
-120 -110 + -115 + -112 + -110 + -115 + -128 + -110 -114 + -114 -112  
Miami Dolphins 457 Dolphins
+1.5 -112 +0.5 -162 + +0.5 -165 + +0.5 -155 + +0.5 -160 +0.5 -150 + +1.5 -158 + -0.5 +130 +1.5 -165 + +1.5 -165 +1.5 -118  
Indianapolis Colts 458 Colts
-1.5 -108 -0.5 +135 + -0.5 +130 + -0.5 +130 + -0.5 +130 -0.5 +120 + -1.5 +130 + +0.5 -170 -1.5 +132 + -1.5 +132 -1.5 -102  
Miami Dolphins 457 Dolphins
o45.5 -110 o9.5 -115 + N/A o9.5 -115 + o9.5 -125 o7.5 -115 + o8.5 -110 + o8.5 -135 o9.5 -118 + o9.5 -118 o47.5 even  
Indianapolis Colts 458 Colts
u45.5 -110 u9.5 -105 + N/A u9.5 -105 + u9.5 -105 u7.5 -115 + u8.5 -110 + u8.5 even u9.5 -105 + u9.5 -105 u47.5 -120  
Miami Dolphins 457 Dolphins
even even + -105 + +102 + even even + +110 + -115 +106 + +106 -108  
Indianapolis Colts 458 Colts
-120 -120 + -120 + -122 + -130 -130 + -134 + -115 -130 + -130 -112  
Miami Dolphins 457 Dolphins
+1.5 -112 +0.5 -120 + N/A +1.5 -135 + +0.5 -115 + N/A -1.5 +115 + N/A +1.5 -150 + +1.5 -150 +1.5 -118  
Indianapolis Colts 458 Colts
-1.5 -108 -0.5 even + N/A -1.5 +114 + -0.5 -105 + N/A +1.5 -135 + N/A -1.5 +120 + -1.5 +120 -1.5 -102  
Miami Dolphins 457 Dolphins
o45.5 -110 o23.5 -110 + N/A o23.5 -110 + o23.5 even + N/A o23.5 -100 + N/A o23.5 -103 + o23.5 -103 o47.5 even  
Indianapolis Colts 458 Colts
u45.5 -110 u23.5 -110 + N/A u23.5 -110 + u23.5 -120 + N/A u23.5 -120 + N/A u23.5 -121 + u23.5 -121 u47.5 -120  
Miami Dolphins 457 Dolphins
even -105 + N/A -105 + N/A N/A -120 + N/A -109 + -109 -108  
Indianapolis Colts 458 Colts
-120 -115 + N/A -115 + N/A N/A +102 + N/A -114 + -114 -112  
Miami Dolphins 457 Dolphins
+1.5 -112 N/A N/A -0.5 +120 + +1.5 -145 + N/A +1.5 -146 + N/A N/A N/A +1.5 -118  
Indianapolis Colts 458 Colts
-1.5 -108 N/A N/A +0.5 -142 + -1.5 +122 + N/A -1.5 +120 + N/A N/A N/A -1.5 -102  
Miami Dolphins 457 Dolphins
o45.5 -110 o13.5 -110 + N/A o13.5 -112 + o14.5 +105 + N/A o14.5 +102 + N/A N/A N/A o47.5 even  
Indianapolis Colts 458 Colts
u45.5 -110 u13.5 -110 + N/A u13.5 -108 + u14.5 -125 + N/A u14.5 -126 + N/A N/A N/A u47.5 -120  
Miami Dolphins 457 Dolphins
even -105 + N/A -112 + -105 + N/A -104 + N/A N/A N/A -108  
Indianapolis Colts 458 Colts
-120 -115 + N/A -108 + -115 + N/A -118 + N/A N/A N/A -112  
Miami Dolphins 457 Dolphins
+1.5 -112 N/A N/A +0.5 -155 + -1.5 +130 + N/A -1.5 +130 + N/A N/A N/A +1.5 -118  
Indianapolis Colts 458 Colts
-1.5 -108 N/A N/A -0.5 +130 + +1.5 -155 + N/A +1.5 -160 + N/A N/A N/A -1.5 -102  
Miami Dolphins 457 Dolphins
o45.5 -110 o9.5 -125 + N/A o9.5 -125 + o9.5 -125 + N/A o9.5 -124 + N/A N/A N/A o47.5 even  
Indianapolis Colts 458 Colts
u45.5 -110 u9.5 +105 + N/A u9.5 +105 + u9.5 +105 + N/A u9.5 +102 + N/A N/A N/A u47.5 -120  
Miami Dolphins 457 Dolphins
even -105 + N/A -105 + -125 + N/A -130 + N/A N/A N/A -108  
Indianapolis Colts 458 Colts
-120 -115 + N/A -115 + +105 + N/A +106 + N/A N/A N/A -112  
Miami Dolphins 457 Dolphins
+1.5 -112 +0.5 -136 + N/A +0.5 -135 + -1.5 +135 + N/A -1.5 +138 + N/A N/A N/A +1.5 -118  
Indianapolis Colts 458 Colts
-1.5 -108 -0.5 +115 + N/A -0.5 +114 + +1.5 -160 + N/A +1.5 -170 + N/A N/A N/A -1.5 -102  
Miami Dolphins 457 Dolphins
o45.5 -110 o13.5 -105 + N/A o13.5 -105 + o13.5 +105 + N/A o13.5 +104 + N/A N/A N/A o47.5 even  
Indianapolis Colts 458 Colts
u45.5 -110 u13.5 -115 + N/A u13.5 -115 + u13.5 -125 + N/A u13.5 -128 + N/A N/A N/A u47.5 -120  
Miami Dolphins 457 Dolphins
even -105 + N/A -108 + -115 + N/A -110 + N/A N/A N/A -108  
Indianapolis Colts 458 Colts
-120 -115 + N/A -112 + -105 + N/A -110 + N/A N/A N/A -112  

The Dolphins will take on the Colts in this week's NFL action. Kickoff is set for 1:00 p.m. EDT at Lucas Oil Stadium in Indianapolis, Ind. The game will be broadcast live on CBS. Here's everything you need to know about Dolphins vs. Colts odds, the latest NFL spreads, NFL over/unders and more.

The Colts opened as a -1.5 point favorite over Dolphins. The total is set at over/under 46.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 9/5/25

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Miami Dolphins vs. Indianapolis Colts Best Bet

Jonathan Taylor played in 14 games last season and went over this line in 9 of them, including games with Anthony Richardson at QB with him siphoning some carries away. It’s also nice to see that down the stretch last season, the Colts really turned the offense over to Taylor, giving just 14 rushing attempts to other RBs over the team's last 5 games.

Taylor enters the season fully healthy with no threat behind him to steal work, as they may have the weakest RB depth in the league behind Taylor. Indoors in perfect conditions, Taylor should have no trouble breaking off a big run or two as a threat to lead the league in rushing attempts and yards for Week 1. I would play this to these odds at 17.5 yards.

Dolphins vs. Colts Best Bet: Jonathan Taylor Longest Rush Over 17.5 Yards

(Pick from Brit Devine)


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What Time is the Miami Dolphins vs. Indianapolis Colts Game?

The Miami Dolphins will take on the Indianapolis Colts at 1:00 ET on Sunday, September 7th.

Where is the Miami Dolphins vs. Indianapolis Colts Game Being Played?

This game is going to be played at Lucas Oil Stadium in Indianapolis, Indiana.

How Can I Watch Miami vs. Indianapolis?

You can watch Dolphins vs. Colts on CBS.

Can the Colts Beat the Dolphins?

With this game practically at a pick 'em, it wouldn't be a surprise if either team came out on top here.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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