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Featured Last Updated Sep 12 2025, 11:10 AM

NFL: Eagles vs. Chiefs, Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
NFL: Eagles vs. Chiefs, Prediction, Odds, Best Bet

Featured Image Credit: Bill Streicher via Imagn Images

PHI @ KC Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Philadelphia Eagles 273 Eagles
+1.5 -110 -0.5 even + +0.5 -140 + +0.5 -125 + PK -110 + -0.5 even + -1.5 +120 + -0.5 +105 -1.5 +115 + -1.5 +115 -1.5 -108  
Kansas City Chiefs 274 Chiefs
-1.5 -110 +0.5 -120 + -0.5 +105 + -0.5 +105 + PK -110 + +0.5 -130 + +1.5 -140 + +0.5 -130 +1.5 -143 + +1.5 -143 +1.5 -112  
Philadelphia Eagles 273 Eagles
o45.5 -110 o23 -110 + N/A o22.5 -122 + o23 -110 + N/A o23.5 -110 + o22.5 -130 o22.5 -127 + o22.5 -127 o46.5 -118  
Kansas City Chiefs 274 Chiefs
u45.5 -110 u23 -110 + N/A u22.5 +102 + u23 -110 + N/A u23.5 -110 + u22.5 +105 u22.5 even + u22.5 even u46.5 -102  
Philadelphia Eagles 273 Eagles
even -115 + N/A -110 + -110 + -125 + -112 + -110 -117 + -117 -125  
Kansas City Chiefs 274 Chiefs
-120 -105 + N/A -110 + -110 + -105 + -108 + -110 -107 + -107 +105  
Philadelphia Eagles 273 Eagles
+1.5 -110 -0.5 +135 + -0.5 +140 + +0.5 -162 + -0.5 +130 + -0.5 +130 + +1.5 -182 + -0.5 +135 -2.5 +150 + -2.5 +150 -1.5 -108  
Kansas City Chiefs 274 Chiefs
-1.5 -110 +0.5 -160 + +0.5 -180 + -0.5 +136 + +0.5 -160 + +0.5 -170 + -1.5 +148 + +0.5 -175 +2.5 -190 + +2.5 -190 +1.5 -112  
Philadelphia Eagles 273 Eagles
o45.5 -110 o7.5 -120 + N/A o9.5 -110 + o7.5 -130 + o9.5 -110 + o8.5 -112 + o8.5 -120 o9.5 -107 + o9.5 -107 o46.5 -118  
Kansas City Chiefs 274 Chiefs
u45.5 -110 u7.5 even + N/A u9.5 -110 + u7.5 even + u9.5 -120 + u8.5 -108 + u8.5 -110 u9.5 -115 + u9.5 -115 u46.5 -102  
Philadelphia Eagles 273 Eagles
even -115 + N/A -108 + -115 + -125 + -110 + -120 -112 + -112 -125  
Kansas City Chiefs 274 Chiefs
-120 -105 + N/A -112 + -115 + -105 + -110 + -110 -112 + -112 +105  
Philadelphia Eagles 273 Eagles
+1.5 -110 -0.5 -105 + N/A -1.5 even + -0.5 -105 + N/A -1.5 +120 + N/A -1.5 +110 + -1.5 +110 -1.5 -108  
Kansas City Chiefs 274 Chiefs
-1.5 -110 +0.5 -115 + N/A +1.5 -120 + +0.5 -115 + N/A +1.5 -140 + N/A +1.5 -137 + +1.5 -137 +1.5 -112  
Philadelphia Eagles 273 Eagles
o45.5 -110 o23.5 -115 + N/A o23.5 -115 + o22.5 -110 + N/A o22.5 -110 + N/A o23.5 -115 + o23.5 -115 o46.5 -118  
Kansas City Chiefs 274 Chiefs
u45.5 -110 u23.5 -105 + N/A u23.5 -105 + u22.5 -110 + N/A u22.5 -110 + N/A u23.5 -108 + u23.5 -108 u46.5 -102  
Philadelphia Eagles 273 Eagles
even -125 + N/A -125 + N/A N/A -112 + N/A -121 + -121 -125  
Kansas City Chiefs 274 Chiefs
-120 +105 + N/A +105 + N/A N/A -104 + N/A -104 + -104 +105  
Philadelphia Eagles 273 Eagles
+1.5 -110 N/A N/A -0.5 +120 + -1.5 +120 + N/A -1.5 +126 + N/A N/A N/A -1.5 -108  
Kansas City Chiefs 274 Chiefs
-1.5 -110 N/A N/A +0.5 -142 + +1.5 -150 + N/A +1.5 -154 + N/A N/A N/A +1.5 -112  
Philadelphia Eagles 273 Eagles
o45.5 -110 o13.5 -105 + N/A o13.5 even + o13.5 -110 + N/A o14.5 +102 + N/A N/A N/A o46.5 -118  
Kansas City Chiefs 274 Chiefs
u45.5 -110 u13.5 -115 + N/A u13.5 -120 + u13.5 -120 + N/A u14.5 -124 + N/A N/A N/A u46.5 -102  
Philadelphia Eagles 273 Eagles
even -120 + N/A -108 + -110 + N/A -114 + N/A N/A N/A -125  
Kansas City Chiefs 274 Chiefs
-120 even + N/A -112 + -110 + N/A -106 + N/A N/A N/A +105  
Philadelphia Eagles 273 Eagles
+1.5 -110 N/A N/A -0.5 +124 + -1.5 +150 + N/A +1.5 -184 + N/A N/A N/A -1.5 -108  
Kansas City Chiefs 274 Chiefs
-1.5 -110 N/A N/A +0.5 -148 + +1.5 -180 + N/A -1.5 +150 + N/A N/A N/A +1.5 -112  
Philadelphia Eagles 273 Eagles
o45.5 -110 o9.5 -135 + N/A o9.5 -130 + o9.5 -120 + N/A o9.5 -116 + N/A N/A N/A o46.5 -118  
Kansas City Chiefs 274 Chiefs
u45.5 -110 u9.5 +115 + N/A u9.5 +110 + u9.5 even + N/A u9.5 -106 + N/A N/A N/A u46.5 -102  
Philadelphia Eagles 273 Eagles
even -120 + N/A -125 + -115 + N/A -110 + N/A N/A N/A -125  
Kansas City Chiefs 274 Chiefs
-120 even + N/A +105 + -105 + N/A -110 + N/A N/A N/A +105  
Philadelphia Eagles 273 Eagles
+1.5 -110 -0.5 even + N/A -0.5 +102 + -1.5 +135 + N/A -1.5 +134 + N/A N/A N/A -1.5 -108  
Kansas City Chiefs 274 Chiefs
-1.5 -110 +0.5 -120 + N/A +0.5 -122 + +1.5 -160 + N/A +1.5 -164 + N/A N/A N/A +1.5 -112  
Philadelphia Eagles 273 Eagles
o45.5 -110 o13.5 -110 + N/A o13.5 -108 + o13.5 -115 + N/A o12.5 -128 + N/A N/A N/A o46.5 -118  
Kansas City Chiefs 274 Chiefs
u45.5 -110 u13.5 -110 + N/A u13.5 -112 + u13.5 -105 + N/A u12.5 +106 + N/A N/A N/A u46.5 -102  
Philadelphia Eagles 273 Eagles
even -135 + N/A -130 + -125 + N/A -114 + N/A N/A N/A -125  
Kansas City Chiefs 274 Chiefs
-120 +115 + N/A +110 + +105 + N/A -106 + N/A N/A N/A +105  

The Eagles will take on the Chiefs in this week's NFL action. Kickoff is set for 4:25 p.m. EDT at GEHA Field at Arrowhead Stadium in Kansas City, Mo. The game will be broadcast live on FOX. Here's everything you need to know about Eagles vs. Chiefs odds, the latest NFL spreads, NFL over/unders and more.

The Eagles opened as a -1.5 point favorite over Chiefs. The total is set at over/under 46.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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Philadelphia Eagles vs. Kansas City Chiefs Best Bet

Boy, what happened to this Chiefs defense? I know, one week, yada yada, but Justin Herbert had never achieved this level of success against Kansas City in his career.

When it was all said and done, K.C. surrendered big chunk after big chunk to push Herbert over 300 yards with three touchdowns, and with things looking murky for the offense, there’s some real concern here entering Week 2.

Philly’s defense stalled out against Dallas, but it’s hard to blame it much against a vintage version of Dak Prescott and an offensive line that silenced the critics with some great push up front to help establish the run.

It’s far from time to ring the alarm for either team, but Philly didn’t look its best on offense while succumbing inside to this Dallas line.

The Chiefs managed to grade out in the top 10 both in pass protection and run blocking last week despite an otherwise flat outing, so coming off Week 1 I think we’ll see this offense kick back into gear – even if Xavier Worthy is out.

I don’t know if we can expect the same out of the defense against a top offense; considering the history with the Chargers, I actually do want to overreact to one week. The total is the only place I’d go.

Eagles vs. Chiefs Best Bet: over 46.5

(Pick from Kenny Ducey)

Looking for more best bets? Check out our free NFL picks and our premium subscription for the best picks!

What Time is the Philadelphia Eagles vs. Kansas City Chiefs Game?

The Philadelphia Eagles will take on the Kansas City Chiefs at 4:25 ET on Sunday, September 14th.

Where is the Kansas City Chiefs vs. Philadelphia Eagles Game Being Played?

This game is going to be played at Arrowhead Stadium in Kansas City, Missouri.

How Can I Watch Chiefs vs. Eagles?

You can watch Chiefs vs. Eagles on FOX.

Can the Chiefs Beat the Eagles?

Considering the short spread, the oddsmakers have made this one very close to a pick 'em type game.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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