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Featured Last Updated Oct 2 2025, 1:50 PM

Detroit Lions vs. Cincinnati Bengals Week 5 Prediction: Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
Detroit Lions vs. Cincinnati Bengals Week 5 Prediction: Odds, Best Bet

Detroit Lions vs. Cincinnati Bengals Odds, NFL Week 5

Image Credit: Junfu Han / USA TODAY NETWORK via Imagn Images

DET @ CIN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Detroit Lions 479 Lions
-1.5 -110 -6.5 -115 + -6.5 -118 + -6.5 -105 + -6.5 -112 + -6.5 -110 + -6.5 -110 + -6.5 -110 + -6.5 -110 -6.5 -110 + -10 -115  
Cincinnati Bengals 480 Bengals
+1.5 -110 +6.5 -105 + +6.5 -102 + +6.5 -115 + +6.5 -109 + +6.5 -120 + +6.5 -110 + +6.5 -110 + +6.5 -110 +6.5 -113 + +10 -105  
Detroit Lions 479 Lions
o50.5 -110 o24.5 -105 + N/A o24.5 -105 + o24.5 -114 + N/A o25.5 -110 + o24.5 -110 + o24.5 -110 o24.5 -112 + o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u24.5 -115 + N/A u24.5 -115 + u24.5 -107 + N/A u25.5 -110 + u24.5 -110 + u24.5 -110 u24.5 -112 + u49.5 -112  
Detroit Lions 479 Lions
-122 -350 + N/A -310 + -335 + -350 + -330 + N/A -350 -375 + -550  
Cincinnati Bengals 480 Bengals
+102 +275 + N/A +250 + +255 + +240 + +270 + N/A +260 +275 + +400  
Detroit Lions 479 Lions
-1.5 -110 -2.5 -125 + -2.5 -135 + -2.5 -120 + N/A -2.5 -125 + -2.5 -122 + -2.5 -120 + -2.5 -125 -2.5 -120 + -10 -115  
Cincinnati Bengals 480 Bengals
+1.5 -110 +2.5 +105 + +2.5 +105 + +2.5 even + N/A +2.5 -105 + +2.5 -100 + +2.5 even + +2.5 -105 +2.5 -104 + +10 -105  
Detroit Lions 479 Lions
o50.5 -110 o9.5 -125 + N/A o9.5 -125 + N/A o9.5 -130 + o9.5 -122 + o9.5 -125 + o10.5 +125 o9.5 -124 + o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u9.5 +105 + N/A u9.5 +102 + N/A u9.5 even + u9.5 -100 + u9.5 +105 + u10.5 -170 u9.5 even + u49.5 -112  
Detroit Lions 479 Lions
-122 -240 + N/A -225 + N/A -240 + -245 + N/A -260 -235 + -550  
Cincinnati Bengals 480 Bengals
+102 +195 + N/A +185 + N/A +170 + +194 + N/A +190 +185 + +400  
Detroit Lions 479 Lions
-1.5 -110 -5 -110 + N/A -5.5 -108 + N/A N/A -4.5 -110 + N/A N/A -5.5 -109 + -10 -115  
Cincinnati Bengals 480 Bengals
+1.5 -110 +5 -110 + N/A +5.5 -112 + N/A N/A +4.5 -110 + N/A N/A +5.5 -114 + +10 -105  
Detroit Lions 479 Lions
o50.5 -110 o23 -110 + N/A o23.5 -112 + N/A N/A o23.5 -110 + o23.5 -120 + N/A o23.5 -114 + o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u23 -110 + N/A u23.5 -108 + N/A N/A u23.5 -110 + u23.5 -110 + N/A u23.5 -109 + u49.5 -112  
Detroit Lions 479 Lions
-122 -240 + N/A -298 + N/A N/A -280 + N/A N/A -335 + -550  
Cincinnati Bengals 480 Bengals
+102 +195 + N/A +235 + N/A N/A +225 + N/A N/A +245 + +400  
Detroit Lions 479 Lions
-1.5 -110 N/A N/A -3.5 -110 + N/A N/A -3.5 -116 + -3.5 -120 + N/A N/A -10 -115  
Cincinnati Bengals 480 Bengals
+1.5 -110 N/A N/A +3.5 -110 + N/A N/A +3.5 -106 + +3.5 -110 + N/A N/A +10 -105  
Detroit Lions 479 Lions
o50.5 -110 o15.5 -110 + N/A o15.5 -110 + N/A N/A o15.5 -112 + o15.5 -125 + N/A N/A o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u15.5 -110 + N/A u15.5 -110 + N/A N/A u15.5 -104 + u15.5 -105 + N/A N/A u49.5 -112  
Detroit Lions 479 Lions
-122 -230 + N/A -258 + N/A N/A -280 + N/A N/A N/A -550  
Cincinnati Bengals 480 Bengals
+102 +190 + N/A +205 + N/A N/A +220 + N/A N/A N/A +400  
Detroit Lions 479 Lions
-1.5 -110 N/A N/A -2.5 -125 + N/A N/A -2.5 -122 + -2.5 -125 + N/A N/A -10 -115  
Cincinnati Bengals 480 Bengals
+1.5 -110 N/A N/A +2.5 +105 + N/A N/A +2.5 +102 + +2.5 -105 + N/A N/A +10 -105  
Detroit Lions 479 Lions
o50.5 -110 o10 even + N/A o9.5 -142 + N/A N/A o9.5 -146 + o9.5 -160 + N/A N/A o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u10 -120 + N/A u9.5 +120 + N/A N/A u9.5 +120 + u9.5 +120 + N/A N/A u49.5 -112  
Detroit Lions 479 Lions
-122 -240 + N/A -238 + N/A N/A -250 + N/A N/A N/A -550  
Cincinnati Bengals 480 Bengals
+102 +195 + N/A +195 + N/A N/A +198 + N/A N/A N/A +400  
Detroit Lions 479 Lions
-1.5 -110 -2.5 -115 + N/A -2.5 -120 + N/A N/A -2.5 -110 + -3.5 even + N/A N/A -10 -115  
Cincinnati Bengals 480 Bengals
+1.5 -110 +2.5 -105 + N/A +2.5 even + N/A N/A +2.5 -110 + +3.5 -130 + N/A N/A +10 -105  
Detroit Lions 479 Lions
o50.5 -110 o13.5 -105 + N/A o13.5 -105 + N/A N/A o13.5 -102 + o13.5 -105 + N/A N/A o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u13.5 -115 + N/A u13.5 -115 + N/A N/A u13.5 -120 + u13.5 -125 + N/A N/A u49.5 -112  
Detroit Lions 479 Lions
-122 -200 + N/A -205 + N/A N/A -196 + N/A N/A N/A -550  
Cincinnati Bengals 480 Bengals
+102 +165 + N/A +170 + N/A N/A +158 + N/A N/A N/A +400  

The Lions will take on the Bengals in this week's NFL action. Kickoff is set for 4:25 p.m. EDT at Paycor Stadium in Cincinnati, Ohio. The game will be broadcast live on FOX. Here's everything you need to know about Lions vs. Bengals odds, the latest NFL spreads, NFL over/unders and more.

The Lions opened as a -10.5 point favorite over Bengals. The total is set at over/under 49.5 total points scored by both teams combined.

Be sure to check out the latest NFL Odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 10/2/25

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Detroit Lions vs. Cincinnati Bengals Best Bet

The Bengals basically admitted to quitting in their pathetic Monday Night Football loss to the Broncos. Sure, they get to go back home, and the Lions have to leave the dome, but the Lions’ offense is going to name their score against this woeful Bengals defense no matter where the game is played. The Lions are averaging 34 points per game through 4 games, despite the 13-point outing against the Packers in Week 1. They also never take their foot off the gas in these spots, consistently putting up huge scores on inferior opponents.

Detroit Lions vs. Cincinnati Bengals Best Bet: Detroit Lions o30.5 Team Total (-115)

(Pick via Erik Beimfohr)


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What Time is the Detroit Lions vs. Cincinnati Bengals Game?

The Detroit Lions and Cincinnati Bengals play at 4:25 PM ET on Sunday, October 5th.

Where is the Detroit Lions vs. Cincinnati Bengals Game Being Played?

This game is going to be played at Paycor Stadium in Cincinnati, Ohio.

How Can I Watch the Detroit Lions vs. Cincinnati Bengals?

You can watch Detroit Lions vs. Cincinnati Bengals on FOX.

Can The Bengals Beat The Lions?

The Bengals are 10.5 point underdogs, but anything can happen in the NFL.

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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