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Detroit Lions vs. Cincinnati Bengals Week 5 Prediction: Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
Detroit Lions vs. Cincinnati Bengals Week 5 Prediction: Odds, Best Bet

Detroit Lions vs. Cincinnati Bengals Odds, NFL Week 5

Image Credit: Junfu Han / USA TODAY NETWORK via Imagn Images

DET @ CIN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
Detroit Lions 479 Lions
-1.5 -110 -6 -105 -6.5 -105 -7.5 +105 -6.5 -102 -6.5 -105 -6.5 -125 -14.5 +110 -6.5 -124 -10.5 -102  
Cincinnati Bengals 480 Bengals
+1.5 -110 +6 -115 +6.5 -115 +7.5 -125 +6.5 -120 +6.5 -115 +6.5 +105 +14.5 -150 +6.5 even +10.5 -118  
Final
Detroit Lions 479 Lions
o50.5 -110 o24.5 -105 N/A o25.5 -112 o24.5 -112 o25.5 -110 o26.5 -105 o26.5 -140 o24.5 -112 o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u24.5 -115 N/A u25.5 -108 u24.5 -109 u25.5 -110 u26.5 -115 u26.5 +105 u24.5 -112 u49.5 -112  
Final
Detroit Lions 479 Lions
-122 -300 N/A -410 -335 -350 N/A -3000 -420 -600  
Cincinnati Bengals 480 Bengals
+102 +240 N/A +320 +245 +250 N/A +1200 +310 +425  
Final
Detroit Lions 479 Lions
-1.5 -110 -2.5 -125 -2.5 -120 -3.5 -112 N/A -2.5 -116 -3.5 -120 -8.5 -115 -3.5 even -10.5 -102  
Cincinnati Bengals 480 Bengals
+1.5 -110 +2.5 +105 +2.5 -105 +3.5 -108 N/A +2.5 -106 +3.5 -110 +8.5 -115 +3.5 -124 +10.5 -118  
Final
Detroit Lions 479 Lions
o50.5 -110 o9.5 -130 N/A o9.5 -142 N/A o9.5 -130 o9.5 -150 o10.5 -135 o9.5 -127 o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u9.5 +110 N/A u9.5 +120 N/A u9.5 +106 u9.5 +115 u10.5 even u9.5 +102 u49.5 -112  
Final
Detroit Lions 479 Lions
-122 -225 N/A -355 N/A -220 N/A -3500 -345 -600  
Cincinnati Bengals 480 Bengals
+102 +185 N/A +280 N/A +172 N/A +8000 +265 +425  
Final
Detroit Lions 479 Lions
-1.5 -110 -6 -110 N/A -3.5 -110 N/A -4.5 -110 N/A -2.5 -115 -3.5 -112 -10.5 -102  
Cincinnati Bengals 480 Bengals
+1.5 -110 +6 -110 N/A +3.5 -110 N/A +4.5 -110 N/A +2.5 -115 +3.5 -112 +10.5 -118  
Final
Detroit Lions 479 Lions
o50.5 -110 o23.5 -110 N/A o23.5 -108 N/A o23.5 -110 o23.5 -115 o22.5 -125 o23.5 -105 o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u23.5 -110 N/A u23.5 -112 N/A u23.5 -110 u23.5 -115 u22.5 -105 u23.5 -120 u49.5 -112  
Final
Detroit Lions 479 Lions
-122 -245 N/A -218 N/A -290 N/A -175 -220 -600  
Cincinnati Bengals 480 Bengals
+102 +205 N/A +180 N/A +245 N/A +135 +170 +425  
Final
Detroit Lions 479 Lions
-1.5 -110 N/A N/A -3.5 -110 N/A -3.5 -118 -3.5 -105 -4.5 -110 N/A -10.5 -102  
Cincinnati Bengals 480 Bengals
+1.5 -110 N/A N/A +3.5 -110 N/A +3.5 -106 +3.5 -125 +4.5 -120 N/A +10.5 -118  
Final
Detroit Lions 479 Lions
o50.5 -110 o14 -110 N/A o14.5 -110 N/A o12.5 -112 o15.5 -125 o14.5 -110 N/A o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u14 -110 N/A u14.5 -110 N/A u12.5 -118 u15.5 -105 u14.5 -120 N/A u49.5 -112  
Final
Detroit Lions 479 Lions
-122 -220 N/A -245 N/A -265 N/A -375 N/A -600  
Cincinnati Bengals 480 Bengals
+102 +180 N/A +200 N/A +220 N/A +260 N/A +425  
Final
Detroit Lions 479 Lions
-1.5 -110 N/A N/A -0.5 even N/A -2.5 -126 -0.5 -110 -0.5 +105 N/A -10.5 -102  
Cincinnati Bengals 480 Bengals
+1.5 -110 N/A N/A +0.5 -120 N/A +2.5 +106 +0.5 -120 +0.5 -140 N/A +10.5 -118  
Final
Detroit Lions 479 Lions
o50.5 -110 o10 -105 N/A o9.5 -125 N/A o14.5 -106 o9.5 -140 o10.5 +120 N/A o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u10 -115 N/A u9.5 +105 N/A u14.5 -128 u9.5 +110 u10.5 -165 N/A u49.5 -112  
Final
Detroit Lions 479 Lions
-122 -240 N/A -162 N/A -265 N/A -145 N/A -600  
Cincinnati Bengals 480 Bengals
+102 +195 N/A +136 N/A +210 N/A +110 N/A +425  
Final
Detroit Lions 479 Lions
-1.5 -110 -3 -110 N/A -2.5 -115 N/A -2.5 -110 -3.5 -110 -0.5 -115 N/A -10.5 -102  
Cincinnati Bengals 480 Bengals
+1.5 -110 +3 -110 N/A +2.5 -105 N/A +2.5 -108 +3.5 -120 +0.5 -115 N/A +10.5 -118  
Final
Detroit Lions 479 Lions
o50.5 -110 o13.5 -110 N/A o13.5 -105 N/A o13.5 -104 o13.5 -110 o12.5 -125 N/A o49.5 -108  
Cincinnati Bengals 480 Bengals
u50.5 -110 u13.5 -110 N/A u13.5 -115 N/A u13.5 -112 u13.5 -120 u12.5 -105 N/A u49.5 -112  
Final
Detroit Lions 479 Lions
-122 -220 N/A -198 N/A -210 N/A -165 N/A -600  
Cincinnati Bengals 480 Bengals
+102 +180 N/A +164 N/A +160 N/A +125 N/A +425  

The Lions will take on the Bengals in this week's NFL action. Kickoff is set for 4:25 p.m. EDT at Paycor Stadium in Cincinnati, Ohio. The game will be broadcast live on FOX. Here's everything you need to know about Lions vs. Bengals odds, the latest NFL spreads, NFL over/unders and more.

The Lions opened as a -10.5 point favorite over Bengals. The total is set at over/under 49.5 total points scored by both teams combined.

Be sure to check out the latest NFL Odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 11/23/25

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Detroit Lions vs. Cincinnati Bengals Best Bet

The Bengals basically admitted to quitting in their pathetic Monday Night Football loss to the Broncos. Sure, they get to go back home, and the Lions have to leave the dome, but the Lions’ offense is going to name their score against this woeful Bengals defense no matter where the game is played. The Lions are averaging 34 points per game through 4 games, despite the 13-point outing against the Packers in Week 1. They also never take their foot off the gas in these spots, consistently putting up huge scores on inferior opponents.

Detroit Lions vs. Cincinnati Bengals Best Bet: Detroit Lions o30.5 Team Total (-115)

(Pick via Erik Beimfohr)


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What Time is the Detroit Lions vs. Cincinnati Bengals Game?

The Detroit Lions and Cincinnati Bengals play at 4:25 PM ET on Sunday, October 5th.

Where is the Detroit Lions vs. Cincinnati Bengals Game Being Played?

This game is going to be played at Paycor Stadium in Cincinnati, Ohio.

How Can I Watch the Detroit Lions vs. Cincinnati Bengals?

You can watch Detroit Lions vs. Cincinnati Bengals on FOX.

Can The Bengals Beat The Lions?

The Bengals are 10.5 point underdogs, but anything can happen in the NFL.

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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