NFL: Lions vs. Eagles, Prediction, Odds, Best Bet
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DET @ PHI Odds
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | | |
| | +3.5 -110 | +2.5 -110 | +2.5 -105 | +2.5 -110 | +2.5 even | +2.5 -118 | +2 -105 | +2.5 -105 | +2.5 -104 | +2.5 -110 | |
| | -3.5 -110 | -2.5 -110 | -2.5 -115 | -2.5 -110 | -2.5 -118 | -2.5 -104 | -2 -115 | -2.5 -125 | -2.5 -120 | -2.5 -110 | |
| Final | Open | | | | | | | | | | |
| | o47.5 -110 | o45.5 -110 | o45.5 -110 | o46.5 -108 | o45.5 -115 | o45.5 -108 | o46 -110 | o45.5 -115 | o46.5 -113 | o46.5 -108 | |
| | u47.5 -110 | u45.5 -110 | u45.5 -110 | u46.5 -112 | u45.5 -105 | u45.5 -112 | u46 -110 | u45.5 -115 | u46.5 -110 | u46.5 -112 | |
| Final | Open | | | | | | | | | | |
| | +150 | +120 | +125 | +120 | +118 | +108 | +115 | +115 | +123 | +120 | |
| | -180 | -140 | -150 | -142 | -138 | -126 | -135 | -150 | -152 | -142 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | | |
| | +3.5 -110 | +0.5 -110 | +0.5 -110 | +2.5 -108 | +1.5 -136 | +1.5 -135 | +1.5 -120 | +1.5 +110 | +2.5 -104 | +2.5 -110 | |
| | -3.5 -110 | -0.5 -110 | -0.5 -110 | -2.5 -112 | -1.5 +112 | -1.5 +110 | -1.5 -110 | -1.5 -145 | -2.5 -120 | -2.5 -110 | |
| Final | Open | | | | | | | | | | |
| | o47.5 -110 | o23 -110 | o22.5 -120 | o23.5 even | o23 -109 | o23.5 +105 | o23.5 even | o22.5 -125 | o23.5 -103 | o46.5 -108 | |
| | u47.5 -110 | u23 -110 | u22.5 even | u23.5 -120 | u23 -110 | u23.5 -125 | u23.5 -130 | u22.5 -115 | u23.5 -122 | u46.5 -112 | |
| Final | Open | | | | | | | | | | |
| | +150 | +105 | +110 | +130 | +103 | -100 | N/A | +135 | +140 | +120 | |
| | -180 | -125 | -130 | -155 | -125 | -122 | N/A | -190 | -177 | -142 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | | |
| | +3.5 -110 | +0.5 -155 | +0.5 -155 | +0.5 -145 | N/A | +1.5 -186 | +0.5 -165 | +1.5 +120 | +1.5 -115 | +2.5 -110 | |
| | -3.5 -110 | -0.5 +130 | -0.5 +120 | -0.5 +114 | N/A | -1.5 +152 | -0.5 +125 | -1.5 -160 | -1.5 -108 | -2.5 -110 | |
| Final | Open | | | | | | | | | | |
| | o47.5 -110 | o9.5 even | o9.5 -105 | o8.5 -112 | N/A | o8.5 -112 | o7.5 -110 | o8.5 -155 | o9.5 -108 | o46.5 -108 | |
| | u47.5 -110 | u9.5 -120 | u9.5 -120 | u8.5 -108 | N/A | u8.5 -108 | u7.5 -115 | u8.5 +105 | u9.5 -115 | u46.5 -112 | |
| Final | Open | | | | | | | | | | |
| | +150 | even | +105 | +114 | N/A | -108 | N/A | +190 | +160 | +120 | |
| | -180 | -120 | -135 | -145 | N/A | -112 | N/A | -200 | -200 | -142 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | | |
| | +3.5 -110 | +0.5 -115 | N/A | -1.5 +114 | N/A | +1.5 -130 | N/A | -0.5 -105 | -1.5 +116 | +2.5 -110 | |
| | -3.5 -110 | -0.5 -105 | N/A | +1.5 -145 | N/A | -1.5 +110 | N/A | +0.5 -125 | +1.5 -143 | -2.5 -110 | |
| Final | Open | | | | | | | | | | |
| | o47.5 -110 | o23 -110 | N/A | o22.5 -115 | N/A | o21.5 -110 | o22.5 -125 | o22.5 -125 | o22.5 -129 | o46.5 -108 | |
| | u47.5 -110 | u23 -110 | N/A | u22.5 -105 | N/A | u21.5 -110 | u22.5 -105 | u22.5 -115 | u22.5 +104 | u46.5 -112 | |
| Final | Open | | | | | | | | | | |
| | +150 | -105 | N/A | -118 | N/A | +106 | N/A | -130 | -109 | +120 | |
| | -180 | -115 | N/A | -102 | N/A | -126 | N/A | -120 | -113 | -142 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | | |
| | +3.5 -110 | N/A | N/A | +0.5 -145 | N/A | +1.5 -138 | +0.5 -125 | +1.5 -160 | N/A | +2.5 -110 | |
| | -3.5 -110 | N/A | N/A | -0.5 +114 | N/A | -1.5 +116 | -0.5 -105 | -1.5 +120 | N/A | -2.5 -110 | |
| Final | Open | | | | | | | | | | |
| | o47.5 -110 | o13.5 -110 | N/A | o13.5 -110 | N/A | o14.5 -122 | o13.5 -120 | o12.5 -170 | N/A | o46.5 -108 | |
| | u47.5 -110 | u13.5 -110 | N/A | u13.5 -120 | N/A | u14.5 -110 | u13.5 -110 | u12.5 +115 | N/A | u46.5 -112 | |
| Final | Open | | | | | | | | | | |
| | +150 | even | N/A | -110 | N/A | +102 | N/A | -110 | N/A | +120 | |
| | -180 | -120 | N/A | -120 | N/A | -124 | N/A | -135 | N/A | -142 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | | |
| | +3.5 -110 | N/A | N/A | +0.5 -148 | N/A | +1.5 -162 | +0.5 -150 | -0.5 +105 | N/A | +2.5 -110 | |
| | -3.5 -110 | N/A | N/A | -0.5 +124 | N/A | -1.5 +134 | -0.5 +115 | +0.5 -140 | N/A | -2.5 -110 | |
| Final | Open | | | | | | | | | | |
| | o47.5 -110 | o9.5 -115 | N/A | o9.5 -122 | N/A | o0.5 -106 | o9.5 -115 | o8.5 -140 | N/A | o46.5 -108 | |
| | u47.5 -110 | u9.5 -105 | N/A | u9.5 -110 | N/A | u0.5 -126 | u9.5 -115 | u8.5 -105 | N/A | u46.5 -112 | |
| Final | Open | | | | | | | | | | |
| | +150 | even | N/A | even | N/A | +106 | N/A | -140 | N/A | +120 | |
| | -180 | -120 | N/A | -130 | N/A | -132 | N/A | +105 | N/A | -142 | |
| Time | Open | Bet365 | BetMGM | DraftKings | Caesars | FanDuel | HardRock | Fanatics | RiversCasino | Consensus | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Final | Open | | | | | | | | | | |
| | +3.5 -110 | +0.5 -150 | N/A | +0.5 -130 | N/A | +1.5 -162 | +0.5 -130 | +1.5 -160 | N/A | +2.5 -110 | |
| | -3.5 -110 | -0.5 +125 | N/A | -0.5 even | N/A | -1.5 +132 | -0.5 even | -1.5 +115 | N/A | -2.5 -110 | |
| Final | Open | | | | | | | | | | |
| | o47.5 -110 | o13.5 -105 | N/A | o13.5 even | N/A | o12.5 -124 | o13.5 -105 | o12.5 -140 | N/A | o46.5 -108 | |
| | u47.5 -110 | u13.5 -115 | N/A | u13.5 -120 | N/A | u12.5 +102 | u13.5 -125 | u12.5 -105 | N/A | u46.5 -112 | |
| Final | Open | | | | | | | | | | |
| | +150 | -105 | N/A | even | N/A | -105 | N/A | -115 | N/A | +120 | |
| | -180 | -115 | N/A | -130 | N/A | -115 | N/A | -135 | N/A | -142 | |
The Lions will take on the Eagles in this week's NFL action. Kickoff is set for 8:20 p.m. EST at Lincoln Financial Field in Philadelphia, Pa. The game will be broadcast live on NBC/Peacock. Here's everything you need to know about Lions vs. Eagles odds, the latest NFL spreads, NFL over/unders and more.
The Eagles opened as a -2.5 point favorite over Lions. The total is set at over/under 46.5 total points scored by both teams combined.
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Updated on 12/7/25

Detroit Lions vs. Philadelphia Eagles Best Bet
The key to handicapping this game could come in the injury report, where the Lions are listing just about every one of their players. Offensively, Penei Sewell is questionable at tackle — arguably the most impactful player we'll mention — while Aidan Hutchinson's status is very much up in the air as well.
The team's already down Marcus Davenport and D.J. Reed on defense — both of whom are on injured reserve — and it looks like starting corners Amik Robinson and Terrion Arnold will join them.
So, before we can even focus on the Sewell news, we are looking at a defense that's going to be down three starting corners and could be missing their best edge rusher as well for a defensive line that's already been worn thin by injury.
Does that make you want to bet on the Eagles here? I mean, it's no secret this offense has been worse, but they're still taking care of the football — even if they can't take care of Jalen Hurts. Philly's doing the little things right in that regard, ranking first in giveaways per game, and the offense has actually looked pretty good when it's decided to throw the ball — something it rarely does.
If the Eagles do throw — and that's a big if for a team that's thrown at the third-lowest clip this season — they should find plenty of success given the injuries reported above. They likely won't find any success on the ground against this run defense, but they have not run well this season.
So, what does that mean? I think it means we bet on the Eagles, holding our nose as we do so. The Lions are excellent against man coverage which could be something of an issue given Philly's man-heavy scheme, but the Lions really aren't going to hurt you much through the air given their tendency to throw short.
Mix in the Sewell injury against an Eagles pass rush which is right around the top 10 and I think you have your answer here.
Lions vs. Eagles Best Bet: Lean Eagles -2.5
(Pick from Kenny Ducey)
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What Time is the Detroit Lions vs. Philadelphia Eagles Game?
The Detroit Lions vs. Philadelphia Eagles game is at 8:15 PM ET on Sunday, November 16th.
Where is the Detroit Lions vs. Philadelphia Eagles Game Being Played?
This game will be played at Lincoln Financial Field in Philadelphia, PA.
How Can I Watch Detroit Lions vs. Philadelphia Eagles?
You can watch Lions vs. Eagles on NBC.
Can the Lions Beat the Eagles?
Yes, the Vegas oddsmakers are expecting a close one here with such a close spread.