49ers @ Rams

San Francisco 49ers
San Francisco 49ers
o47.5
o47.5 / -5.5
NFL -
Los Angeles Rams
Los Angeles Rams
-5.5

SF @ LA Odds

49ers injuries

Pos Player Status
WR Ricky Pearsall (Knee) Out
QB Brock Purdy (Toe) Out
WR Ricky Pearsall (Knee) Questionable
QB Brock Purdy (Toe) Questionable
WR Ricky Pearsall (Knee) Out
QB Brock Purdy (Toe) Out
WR Jauan Jennings (Ribs) Questionable
WR Ricky Pearsall (Knee) Questionable
QB Brock Purdy (Toe) Questionable
TE George Kittle (Hamstring) Questionable
QB Mac Jones (Oblique) Questionable
WR Ricky Pearsall (Knee) Out
WR Ricky Pearsall (Knee) Doubtful
WR Jauan Jennings (Ankle) Questionable
WR Ricky Pearsall (Knee) Questionable

Rams injuries

Pos Player Status
WR Tutu Atwell (Hamstring) Out
WR Puka Nacua (Ankle) Questionable
TE Colby Parkinson (Concussion) Questionable
RB Blake Corum (Ankle) Questionable
WR Tutu Atwell (Hamstring) Questionable
WR Puka Nacua (Ankle) Out
WR Tutu Atwell (Hamstring) Out
TE Colby Parkinson (Concussion) Out
TE Colby Parkinson (Concussion) Questionable
WR Tutu Atwell (Hamstring) Questionable
TE Tyler Higbee (Hip) Questionable

SF @ LA Line Movements

Spread

Open: LA -1.5
-1.5 -2.9 -4.3 -5.7 -7.1 -8.5
  • 5/15 12:58am
  • LA -1.5
  • 9/23 07:21pm
  • LA -3
  • 9/29 11:39am
  • LA -3.5
  • 9/29 03:36pm
  • LA -4.5
  • 9/29 04:46pm
  • LA -5.5
  • 9/30 05:40pm
  • LA -6
  • 9/30 05:58pm
  • LA -6.5
  • 10/01 02:04pm
  • LA -7
  • 10/01 08:13pm
  • LA -7.5
  • 10/02 01:05am
  • LA -8.5
Best Home Odds
Best Away Odds +

Total

Open: o47.5
46.5 46.7 46.9 47.1 47.3 47.5
  • 5/15 12:58am
  • o47.5
  • 9/23 07:21pm
  • o46.5
  • 9/28 11:08pm
  • o47.5
  • 9/29 02:21pm
  • o46.5
  • 9/29 04:06pm
  • o47.5
  • 9/29 04:41pm
  • o46.5
  • 9/29 04:42pm
  • o47.5
  • 9/29 04:46pm
  • o46.5
  • 9/29 04:48pm
  • o47.5
  • 9/29 04:51pm
  • o46.5

Moneyline

Open: SF +102 LA -122
-192 -123.6 -55.2 +13.2 +81.6 +150
  • 5/15 12:58am
  • LA -122
  • 5/16 02:24pm
  • LA -120
  • 5/19 05:41pm
  • LA -122
  • 6/03 07:19am
  • LA -120
  • 6/26 03:54pm
  • LA -122
  • 8/07 07:05pm
  • LA -125
  • 9/23 07:21pm
  • LA -162
  • 9/26 08:46pm
  • LA -155
  • 9/28 11:08pm
  • LA -180
  • 9/29 11:45am
  • LA -192
  • 5/15 12:58am
  • SF +102
  • 5/16 02:24pm
  • SF +100
  • 5/19 05:41pm
  • SF +102
  • 6/03 07:19am
  • SF +100
  • 6/26 03:54pm
  • SF +102
  • 8/07 07:05pm
  • SF +105
  • 9/23 07:21pm
  • SF +136
  • 9/26 08:46pm
  • SF +130
  • 9/28 11:08pm
  • SF +150
  • 9/29 11:45am
  • SF +145
Best Home Odds
Best Away Odds +

Jaguars vs. 49ers Head-to-Head

Date Team Opp Close Result ATS/OU
Sep 28, 2025 49ers Jaguars -3.5 / 45.5 Lost 21-26 Lost / Over
Nov 12, 2023 49ers @Jaguars -3 / 44.5 Won 34-3 Won / Under
Nov 21, 2021 49ers @Jaguars -6.5 / 45.5 Won 30-10 Won / Under
Dec 24, 2017 49ers Jaguars +4 / 43 Won 44-33 Won / Over
Oct 27, 2013 49ers Jaguars +16 / 40 Lost 0-0 Won / Under
Nov 29, 2009 49ers @Jaguars +3 / 42.5 Lost 0-0 Won / Under
Dec 18, 2005 49ers Jaguars -16 / 36.5 Lost 0-0 Lost / Under

49ers vs Rams Odds

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