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Featured Last Updated Dec 16 2025, 12:15 PM

NFL: Jacksonville Jaguars vs. Denver Broncos: Prediction, Odds, Preview

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
NFL: Jacksonville Jaguars vs. Denver Broncos: Prediction, Odds, Preview

Featured Image Credit: Corey Perrine/Florida Times-Union / USA TODAY NETWORK via Imagn Images

JAC @ DEN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Jacksonville Jaguars 123 Jaguars
+5.5 -110 +1.5 -110 + +1.5 -110 + +1.5 -110 + +1.5 -107 + +1.5 -110 + +1.5 -110 + +1.5 -110 + +1.5 -120 + +3 -110  
Denver Broncos 124 Broncos
-5.5 -110 -1.5 -110 + -1.5 -110 + -1.5 -110 + -1.5 -114 + -1.5 -110 + -1.5 -110 + -1.5 -110 + -1.5 -105 + -3 -110  
Jacksonville Jaguars 123 Jaguars
o45.5 -110 o23.5 even + o23.5 even + o22.5 -122 + o23 -108 + o23.5 +105 + o22.5 -125 + o22.5 -125 + o23.5 +105 + o45.5 -110  
Denver Broncos 124 Broncos
u45.5 -110 u23.5 -120 + u23.5 -120 + u22.5 +102 + u23 -112 + u23.5 -125 + u22.5 +105 + u22.5 +105 + u23.5 -130 + u45.5 -110  
Jacksonville Jaguars 123 Jaguars
+180 +125 + +125 + +124 + +121 + +118 + N/A +125 + +114 + +136  
Denver Broncos 124 Broncos
-218 -150 + -150 + -148 + -145 + -144 + N/A -150 + -141 + -162  
Jacksonville Jaguars 123 Jaguars
+5.5 -110 +0.5 -150 + +0.5 -155 + +0.5 -142 + N/A +1.5 -166 + +0.5 -155 + +1.5 -160 + +1.5 -165 + +3 -110  
Denver Broncos 124 Broncos
-5.5 -110 -0.5 +125 + -0.5 +120 + -0.5 +120 + N/A -1.5 +136 + -0.5 +130 + -1.5 +130 + -1.5 +130 + -3 -110  
Jacksonville Jaguars 123 Jaguars
o45.5 -110 o9.5 -105 + o8.5 -118 + o8.5 -115 + N/A o9.5 -108 + o9.5 -110 + o8.5 -120 + o9.5 -112 + o45.5 -110  
Denver Broncos 124 Broncos
u45.5 -110 u9.5 -115 + u8.5 -110 + u8.5 -105 + N/A u9.5 -112 + u9.5 -110 + u8.5 -110 + u9.5 -112 + u45.5 -110  
Jacksonville Jaguars 123 Jaguars
+180 +110 + +110 + +114 + N/A +104 + N/A +110 + +102 + +136  
Denver Broncos 124 Broncos
-218 -130 + -140 + -135 + N/A -128 + N/A -145 + -130 + -162  
Jacksonville Jaguars 123 Jaguars
+5.5 -110 N/A N/A +0.5 -120 + N/A +1.5 -128 + N/A N/A N/A +3 -110  
Denver Broncos 124 Broncos
-5.5 -110 N/A N/A -0.5 -110 + N/A -1.5 +106 + N/A N/A N/A -3 -110  
Jacksonville Jaguars 123 Jaguars
o45.5 -110 o13.5 -105 + N/A o13.5 -110 + N/A o13.5 -118 + N/A N/A N/A o45.5 -110  
Denver Broncos 124 Broncos
u45.5 -110 u13.5 -115 + N/A u13.5 -120 + N/A u13.5 -104 + N/A N/A N/A u45.5 -110  
Jacksonville Jaguars 123 Jaguars
+180 +120 + N/A +110 + N/A +116 + N/A N/A N/A +136  
Denver Broncos 124 Broncos
-218 -140 + N/A -140 + N/A -142 + N/A N/A N/A -162  
Jacksonville Jaguars 123 Jaguars
+5.5 -110 N/A N/A +0.5 -140 + N/A +1.5 -146 + N/A N/A N/A +3 -110  
Denver Broncos 124 Broncos
-5.5 -110 N/A N/A -0.5 +110 + N/A -1.5 +120 + N/A N/A N/A -3 -110  
Jacksonville Jaguars 123 Jaguars
o45.5 -110 o9.5 -115 + N/A o9.5 -125 + N/A o8.5 -116 + N/A N/A N/A o45.5 -110  
Denver Broncos 124 Broncos
u45.5 -110 u9.5 -105 + N/A u9.5 -105 + N/A u8.5 -106 + N/A N/A N/A u45.5 -110  
Jacksonville Jaguars 123 Jaguars
+180 +110 + N/A +110 + N/A +118 + N/A N/A N/A +136  
Denver Broncos 124 Broncos
-218 -130 + N/A -140 + N/A -144 + N/A N/A N/A -162  
Jacksonville Jaguars 123 Jaguars
+5.5 -110 +0.5 -135 + N/A +0.5 -125 + N/A +1.5 -140 + N/A N/A N/A +3 -110  
Denver Broncos 124 Broncos
-5.5 -110 -0.5 +115 + N/A -0.5 -105 + N/A -1.5 +116 + N/A N/A N/A -3 -110  
Jacksonville Jaguars 123 Jaguars
o45.5 -110 o13 -110 + N/A o12.5 -125 + N/A o12.5 -118 + N/A N/A N/A o45.5 -110  
Denver Broncos 124 Broncos
u45.5 -110 u13 -110 + N/A u12.5 -105 + N/A u12.5 -104 + N/A N/A N/A u45.5 -110  
Jacksonville Jaguars 123 Jaguars
+180 even + N/A +105 + N/A +110 + N/A N/A N/A +136  
Denver Broncos 124 Broncos
-218 -120 + N/A -135 + N/A -134 + N/A N/A N/A -162  
Jacksonville Jaguars 123 Jaguars
+5.5 -110 +1 -110 + N/A N/A N/A +1.5 -110 + N/A N/A +1.5 -114 + +3 -110  
Denver Broncos 124 Broncos
-5.5 -110 -1 -110 + N/A N/A N/A -1.5 -110 + N/A N/A -1.5 -109 + -3 -110  
Jacksonville Jaguars 123 Jaguars
o45.5 -110 o22.5 -110 + N/A N/A N/A o21.5 -110 + N/A N/A o21.5 -114 + o45.5 -110  
Denver Broncos 124 Broncos
u45.5 -110 u22.5 -110 + N/A N/A N/A u21.5 -110 + N/A N/A u21.5 -109 + u45.5 -110  
Jacksonville Jaguars 123 Jaguars
+180 +110 + N/A N/A N/A +126 + N/A N/A +116 + +136  
Denver Broncos 124 Broncos
-218 -130 + N/A N/A N/A -148 + N/A N/A -148 + -162  

The Jaguars will take on the Broncos in this week's NFL action. Kickoff is set for 4:05 p.m. EST at Empower Field at Mile High in Denver, Colo. The game will be broadcast live on FOX. Here's everything you need to know about Jaguars vs. Broncos odds, the latest NFL spreads, NFL over/unders and more.

The Broncos opened as a -3 point favorite over Jaguars. The total is set at over/under 45.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 12/16/25

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Jacksonville Jaguars vs. Denver Broncos Prediction

Both of these teams are coming off of big wins, with the Broncos defeating the Packers and the Jaguars destroying the Jets. Both teams looked great, were efficient on offense, and proved themselves as a playoff contender.

As with a few of these other picks, the Broncos have become an auto-fade for as long as they sit atop the Action Network luck rankings. These two teams have a similar statistical profile. If anything, Jacksonville has an offensive edge, and Denver has a defensive one.

Jacksonville can exploit Denver's 3rd-down defense, which ranks outside of the top 10, to keep this AFC matchup close.

Jacksonville Jaguars vs. Denver Broncos Prediction: Jacksonville Jaguars +3 (-105)

(Pick from Dylan Wilkerson)

Looking for more predictions? Check out our free NFL picks and our premium subscription for the best picks!

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What Time is the Jacksonville Jaguars vs. Denver Broncos Game?

The Jacksonville Jaguars vs. Denver Broncos game is at 4:05 PM ET on Sunday, December 21st.

Where is the Jacksonville Jaguars vs. Denver Broncos Game Being Played?

This game will be played at Empower Field at Mile High in Denver, Colo.

How Can I Watch Jacksonville Jaguars vs. Denver Broncos?

You can watch Jacksonville Jaguars vs. Denver Broncos on FOX.

Can the Jaguars Beat the Broncos?

Of course! The Jaguars are a 3 point underdog, anything can happen in the NFL!

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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