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NFL: San Francisco 49ers vs. Chicago Bears: Prediction, Odds, Preview

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
NFL: San Francisco 49ers vs. Chicago Bears: Prediction, Odds, Preview

Featured Image Credit: Cary Edmondson-Imagn Images

CHI @ SF Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
Chicago Bears 429 Bears
+3.5 -110 +2.5 +105 +2.5 even +3.5 -120 +3.5 even +4.5 -120 +5.5 -125 +1.5 -140 +3.5 -114 +4.5 -115  
San Francisco 49ers 430 49ers
-3.5 -110 -2.5 -125 -2.5 -120 -3.5 even -3.5 -127 -4.5 -100 -5.5 -105 -1.5 +105 -3.5 -109 -4.5 -105  
Final
Chicago Bears 429 Bears
o46.5 -110 o25.5 -110 o25.5 -110 o25.5 -115 o26.5 -106 o26.5 -105 o24.5 -120 o36.5 -130 o26.5 -105 o51.5 -108  
San Francisco 49ers 430 49ers
u46.5 -110 u25.5 -110 u25.5 -110 u25.5 -105 u26.5 -121 u26.5 -115 u24.5 even u36.5 -110 u26.5 -120 u51.5 -112  
Final
Chicago Bears 429 Bears
+150 +145 +140 +154 +183 +194 N/A -105 +170 +185  
San Francisco 49ers 430 49ers
-180 -165 -170 -180 -245 -245 N/A -135 -215 -225  
Final
Chicago Bears 429 Bears
+3.5 -110 +0.5 -135 +0.5 -145 +0.5 -130 N/A +2.5 +106 +2.5 +105 -0.5 +125 +2.5 -108 +4.5 -115  
San Francisco 49ers 430 49ers
-3.5 -110 -0.5 +115 -0.5 +110 -0.5 +110 N/A -2.5 -128 -2.5 -135 +0.5 -165 -2.5 -115 -4.5 -105  
Final
Chicago Bears 429 Bears
o46.5 -110 o10 -105 o9.5 -155 o9.5 -142 N/A o9.5 -150 o10.5 +125 o20.5 -180 o9.5 -141 o51.5 -108  
San Francisco 49ers 430 49ers
u46.5 -110 u10 -115 u9.5 +120 u9.5 +120 N/A u9.5 +124 u10.5 -165 u20.5 +120 u9.5 +114 u51.5 -112  
Final
Chicago Bears 429 Bears
+150 +115 +115 +124 N/A +210 N/A -170 +180 +185  
San Francisco 49ers 430 49ers
-180 -135 -145 -148 N/A -265 N/A +120 -230 -225  
Final
Chicago Bears 429 Bears
+3.5 -110 +2.5 -110 N/A +2.5 -120 N/A +1.5 -135 N/A +1.5 -115 +1.5 -148 +4.5 -115  
San Francisco 49ers 430 49ers
-3.5 -110 -2.5 -110 N/A -2.5 -110 N/A -1.5 +115 N/A -1.5 -115 -1.5 +118 -4.5 -105  
Final
Chicago Bears 429 Bears
o46.5 -110 o25.5 -110 N/A o25.5 -112 N/A o24.5 -110 o25.5 -115 o24.5 -125 o24.5 -114 o51.5 -108  
San Francisco 49ers 430 49ers
u46.5 -110 u25.5 -110 N/A u25.5 -108 N/A u24.5 -110 u25.5 -115 u24.5 -115 u24.5 -108 u51.5 -112  
Final
Chicago Bears 429 Bears
+150 +120 N/A +124 N/A +102 N/A +120 -107 +185  
San Francisco 49ers 430 49ers
-180 -140 N/A -160 N/A -120 N/A -170 -115 -225  
Final
Chicago Bears 429 Bears
+3.5 -110 N/A N/A +2.5 -110 N/A +1.5 -110 +2.5 -110 +1.5 -120 N/A +4.5 -115  
San Francisco 49ers 430 49ers
-3.5 -110 N/A N/A -2.5 -120 N/A -1.5 -108 -2.5 -120 -1.5 -110 N/A -4.5 -105  
Final
Chicago Bears 429 Bears
o46.5 -110 o14 -115 N/A o15.5 -115 N/A o24.5 -110 o15.5 -120 o16.5 -110 N/A o51.5 -108  
San Francisco 49ers 430 49ers
u46.5 -110 u14 -105 N/A u15.5 -115 N/A u24.5 -120 u15.5 -110 u16.5 -130 N/A u51.5 -112  
Final
Chicago Bears 429 Bears
+150 +145 N/A +145 N/A +136 N/A +120 N/A +185  
San Francisco 49ers 430 49ers
-180 -170 N/A -188 N/A -164 N/A -170 N/A -225  
Final
Chicago Bears 429 Bears
+3.5 -110 N/A N/A +0.5 -125 N/A -1.5 +134 -0.5 +125 -0.5 +130 N/A +4.5 -115  
San Francisco 49ers 430 49ers
-3.5 -110 N/A N/A -0.5 -105 N/A +1.5 -162 +0.5 -165 +0.5 -170 N/A -4.5 -105  
Final
Chicago Bears 429 Bears
o46.5 -110 o10.5 even N/A o10.5 +105 N/A o14.5 +198 o10.5 +115 o10.5 +115 N/A o51.5 -108  
San Francisco 49ers 430 49ers
u46.5 -110 u10.5 -120 N/A u10.5 -135 N/A u14.5 -280 u10.5 -150 u10.5 -170 N/A u51.5 -112  
Final
Chicago Bears 429 Bears
+150 +125 N/A +120 N/A -124 N/A -120 N/A +185  
San Francisco 49ers 430 49ers
-180 -150 N/A -154 N/A +102 N/A -120 N/A -225  
Final
Chicago Bears 429 Bears
+3.5 -110 +0.5 -120 N/A +0.5 -115 N/A +1.5 -140 N/A +1.5 -125 N/A +4.5 -115  
San Francisco 49ers 430 49ers
-3.5 -110 -0.5 even N/A -0.5 -115 N/A -1.5 +116 N/A -1.5 -105 N/A -4.5 -105  
Final
Chicago Bears 429 Bears
o46.5 -110 o16 -110 N/A o14.5 -105 N/A o14.5 +104 o14.5 even o14.5 -105 N/A o51.5 -108  
San Francisco 49ers 430 49ers
u46.5 -110 u16 -110 N/A u14.5 -125 N/A u14.5 -126 u14.5 -130 u14.5 -140 N/A u51.5 -112  
Final
Chicago Bears 429 Bears
+150 +110 N/A +114 N/A +114 N/A +120 N/A +185  
San Francisco 49ers 430 49ers
-180 -130 N/A -145 N/A -140 N/A -170 N/A -225  

The Bears will take on the 49ers in this week's NFL action. Kickoff is set for 8:20 p.m. EST at Levi's Stadium in Santa Clara, Calif. The game will be broadcast live on NBC/Peacock. Here's everything you need to know about Bears vs. 49ers odds, the latest NFL spreads, NFL over/unders and more.

The 49ers opened as a -2.5 point favorite over Bears. The total is set at over/under 50.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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San Francisco 49ers vs. Chicago Bears Prediction

The 49ers have a lot of things going for them in this matchup. They rank 8th in red-zone touchdown conversion rate, where Chicago ranks 16th. The 49ers rank 2nd in 3rd-down EPA/play, where Chicago ranks 9th. The 49ers are also more efficient at moving the ball through the air, and the rush attacks for these two teams are comparable.

Brock Purdy will be spreading the love early and often in this game, looking to expose a Chicago pass defense that is less than stellar. That will be the winning recipe for the 49ers.

San Francisco 49ers vs. Chicago Bears Prediction: San Francisco 49ers -2.5 (-115)

(Pick from Dylan Wilkerson)

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What Time is the San Francisco 49ers vs. Chicago Bears Game?

The San Francisco 49ers vs. Chicago Bears game is at 8:20 PM ET on Sunday, December 28th.

Where is the San Francisco 49ers vs. Chicago Bears Game Being Played?

This game will be played at Levi's Stadium in Santa Clara, Calif.

How Can I Watch San Francisco 49ers vs. Chicago Bears?

You can watch San Francisco 49ers vs. Chicago Bears on NBC/Peacock.

Can the 49ers Beat the Bears?

Of course! The 49ers are a 2.5 point favorite, so the oddsmakers think they will win. However, anything can happen in the NFL!

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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