NFL Odds Week 11: Buccaneers vs 49ers Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

3 minute read

Week 11 of the NFL season continues with a matchup between teams trending in opposite directions in the NFC as the Tampa Bay Buccaneers visit the San Francisco 49ers. The betting odds see San Francisco as a 11.5-point favorite coming off an impressive win over Jacksonville last week. Coverage begins from Levi's Stadium in Santa Clara on Sunday, November 19 at 4:05 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for Week 11: Buccaneers vs 49ers Lines, Spreads, Betting Trends: the opening lines, spreads, betting trends and more. Stay tuned for more details regarding our ESPN BET promo code as well!

Tampa Bay Buccaneers vs San Francisco 49ers Odds

• Opening point spread: 49ers -10.5
• Opening moneyline: 49ers -650/Buccaneers +450
• Opening total: Over/Under 42 points scored
• Time: 4:05 p.m. ET Sunday (FOX)

UPDATE 3:45 P.M. ET SUNDAY: Shortly before kickoff, the Niners are 13.5-point favorites at DraftKings Sportsbook. That's after opening a week ago at San Fran -10.5 and hitting multiple numbers on the way up the past seven days.

San Francisco is getting 62% of spread tickets/77% of spread money.

The total opened at 42.5, bottomed out at 41 multiple times early in the week and is now 41.5. The Over is netting 80% of tickets/77% of money.

UPDATE NOON ET FRIDAY: San Fran advanced from -10.5 to -11 Monday in BetMGM's NFL odds Week 11 market. On Wednesday, the Niners ticked up to -11.5, where the line remains now.

Early ticket count is 2.5/1 and early money 9/1 on the double-digit favorite 49ers.

The total is down a point at BetMGM, dipping from 42.5 to 42/41.5 on Monday. The Over is drawing 70% of tickets, while 55% of money is on the Under.

UPDATE 11 P.M. ET SUNDAY: Entering Week 10 on a three-game losing skid, San Francisco was due to get right – and did so in impressive fashion. The Niners (6-3 SU/5-4 ATS) blasted a hot Jacksonville squad 34-3 laying 3 points on the road.

Tampa Bay (4-5 SU/5-4 ATS) snapped a four-game SU skid by breezing past Tennessee 20-6 as 2.5-point home chalk.

The Bucs-Niners spread and total didn't move tonight on The SuperBook's NFL Week 11 odds board.

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 11 Report containing spreads, lines, and trends for every NFL matchup.

Buccaneers vs 49ers Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

The Bucs can't run the ball to save their lives, but Tampa Bay's pass protection has been strong and should give Baker Mayfield time to test San Francisco's one real defensive weak spot, its corners. The 49ers are beatable on the outside, so Chris Godwin and especially Mike Evans can win and help Tampa move the ball.

Usually I play Mike Evans for a touchdown, and he's scored in six of nine games this season, but it's tough to bet on a touchdown against a tough defense. The yardage total sticks out as the better play as Evans has at least 39 yards every game this season, which gives him a safe floor that puts him within one catch of the over. Also, he's gone over 55.5 yards in six of nine games (67%).

Pick: Mike Evans Over 55.5 Receiving Yards (-110)

For more NFL picks, check out Action Network's NFL Week 11: How to Bet Every Game & Every Team.

The One Stat to Know About Buccaneers vs 49ers

Action Network NFL researcher Evan Abrams offers his top betting stat:

Until Bengals loss, 49ers had covered 10 straight at home. 49ers are 16-3 ATS at home in their last 19 games

For more NFL betting stats, check out Action Network's NFL Week 11 Betting Trends, Stats, Notes.

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Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson