NFL Odds Week 14: Seahawks vs 49ers Lines, Spreads, Betting Trends

Patrick Everson Sports Betting Expert

4 minute read

Week 14 of the NFL season continues with a heavyweight NFC West showdown between the Seattle Seahawks and San Francisco 49ers. The betting odds see the Niners as 10.5-point home favorites coming off a blowout road win in Philly. Coverage begins from Levi's Stadium in Santa Clara on Sunday, December 10 at 4:05 p.m. ET on FOX.

Here's everything you need to know about the NFL odds for Week 14: Seahawks vs. 49ers lines, spreads, betting trends and more.

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Seattle Seahawks vs San Francisco 49ers Odds

• Opening point spread: 49ers -12.5
• Opening moneyline: 49ers -600/Seahawks +425
• Opening total: Over/Under 45.5 points scored
• Time: 4:05 p.m. ET Sunday (FOX)

UPDATE 3:30 P.M. ET SUNDAY: As kickoff approaches, San Fran is all the way out to -14.5 at DraftKings. That movement was even before news in the past hour that Seattle QB Geno Smith (groin) is definitely out today.

The 49ers opened -11.5 and fell back to -10.5, then went to -11 Thursday. But as Smith's status became much more cloudy, the line took off. San Francisco vaulted to -12/-12.5/-13 Friday, then hit -13.5 Saturday and -14/-14.5 this afternoon.

All that noted, it's two-way spread play at DK, with 54% of tickets on the Niners and 53% of cash on the Seahawks.

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The total opened at 46, peaked at 47 early in the week and has been sliding throughout the weekend. It's now at 44.5, although tickets are 3/1 and money almost 4/1 on the Over.

UPDATE MIDNIGHT ET WEDNESDAY: TwinSpires opened San Fran -12.5 on the NFL Week 14 odds board. The Niners made a stop at -11.5 on the way down to -10.5. San Francisco is getting 63% of spread tickets and 52% of spread cash.

"Sharp play on the Seahawks, in what could be a letdown spot for the 49ers," Lucas said.

The total is up a point from 45.5 to 46.5, with tickets 2/1 and money 2.5/1 on the Over.

UPDATE 10 P.M. ET SUNDAY: In Week 13, San Francisco (9-3 SU/7-5 ATS) flexed its muscle as arguably the best team in the NFL. The Niners went to Philadelphia as a 3-point fave and thumped the Eagles 42-19. San Fran has won four in a row, all by double digits.

Seattle (6-6 SU/5-7-1 ATS) has lost three in a row and four of its last five SU. In Week 13, the Seahawks gave Dallas all it could handle, but lost 41-35 getting 9.5 points on the road.

"San Francisco has turned back into the buzzsaw it was early in the season," Michaelson said. "Seattle played hard against Dallas, but there's a significant talent gap between these two teams. I think the line reflects that. I could see the market moving this back toward 10, but we'll likely be looking for the Seahawks to cover."

So far, though, the number hasn't budged off 49ers -12.5. The total is up a half-point to 46.

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 14 Report containing spreads, lines, and trends for every NFL matchup.

Seahawks vs 49ers Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

Look, I'm not going to pretend to make an actual case for Seattle. You watched the games against San Francisco. These games have been over by the end of the first quarter, and betting against the 49ers feels like stepping in front of a speeding train right now. But that's exactly why there's value on the number.

Trends love this spot for Seattle. In division games Week 14 and later, an underdog that lost by 8-to-20 points in the previous matchup between two teams is 58% ATS in the rematch, and 'dogs that failed to cover by 7-to-14 points are 59% ATS in the rematch. Geno Smith is 71% ATS as a division underdog and 70% ATS as a 'dog of over a touchdown, and Pete Carroll is 63% ATS as a division 'dog and 61% ATS after a loss.

Close your eyes, swallow hard, and bet the trends for a desperate team in a good situational spot.

Pick: Seahawks +10.5

For more NFL picks, check out Action Network's NFL Week 14: How to Bet Every Game & Every Team.

The One Stat to Know About Seahawks vs 49ers

Action Network NFL researcher Evan Abrams offers his top betting stat:

Seahawks: Geno Smith is 22-17-2 ATS as a dog, but only 10-13 ATS as a favorite.

For more NFL betting stats, check out Action Network's NFL Week 14 Betting Trends, Stats, Notes.

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Patrick Everson

Patrick Everson is a senior reporter for VegasInsider. Based in Las Vegas since 1994, he's worked in the sports betting journalism/content space for more than a decade. He's most known for his deep roster of contacts behind sportsbook counters, providing readers and viewers with the ins-and-outs of how events are being bet. He's also a thought leader in the sports betting space, often appearing on or moderating panels at national conferences. More from Patrick Everson