NFL Odds Week 3: Rams vs Bengals Lines, Spreads, Betting Trends

Matchup Spread Total Moneyline

NFL Week 3 odds are in the spotlight, with the regular season in full swing as the Rams take on the Bengals on Monday, September 25. Coverage begins from Paycor Stadium in Cincinnati at 8:15 p.m. ET on ESPN.

Here's everything you need to know about the NFL odds for Week 3 Rams vs. Bengals: the opening lines, spreads, betting trends and more. Check back regularly for updates.

Los Angeles Rams vs Cincinnati Bengals Odds

Joe Burrow's Cincinnati Bengals need a win in the Week 3 Monday nighter. (Getty)
  • Opening point spread: Bengals -6.5
  • Opening moneyline: Bengals -130/Rams Rams +110
  • Opening total: Over/Under 46.5 points scored
  • Time: 8:15 p.m. ET Monday (ESPN)

UPDATE 5 P.M. ET WEDNESDAY: At TwinSpires, the lookahead line for this game was Bengals -7.5. But that was before Joe Burrow re-aggravated a calf injury in Cincy's Week 2 loss to Baltimore.

TwinSpires reopened at Cincinnati -5, fell to -3.5 in short order and is now at -2.5. Ticket count is 2.5/1 and money 2/1 on the road underdog Rams.

"It's majority Rams money so far, with the unknown status of Burrow," Lucas said.

The total slid from 46 to 43.5, with 59% of early tickets/67% of early money on the Under.

UPDATE 11:30 P.M. ET SUNDAY: Cincinnati is 0-2 SU and ATS, with both losses coming in AFC North play. Against Baltimore in Week 2, the Bengals fell 27-24 giving 3 points at home.

Los Angeles (1-1 SU and ATS) lost to San Francisco 30-23, but covered as a 7.5-point 'dog. Trailing 30-20, the Rams kicked an otherwise completely meaningless 38-yard field goal as time expired – but it mattered for spread bettors.

The Rams and Bengals met in Super Bowl 56 two seasons ago, with the Rams winning 23-20 as 4.5-point faves.

"It's been all Rams action early in this one, which isn't too surprising, just based off how both teams have looked through the first two weeks," Degnon said. "I think that will balance out more as the week goes on. If not on straight bets, I'm sure there will be some parlay liability building up on the Bengals, who have started 0-2 and in the eyes of the public are staring down a must-win come Monday night.

"We've also taken some Over money, but not enough to move us off the opener."

Click here for Vegas Insider senior reporter Patrick Everson's full NFL Odds Week 3 Report containing spreads, lines, and trends for every NFL matchup.

Rams vs Bengals Pick, Prediction

Action Network NFL betting expert Brandon Anderson offers this prediction:

As of Thursday night, we still don't know whether Joe Burrow will play. He hasn't practiced this week and hasn't looked like himself this season, but the latest line movement seems to indicate optimism he'll play. If Burrow sits, backup Jake Browning and his one career pass attempt would get the start.

Needless to say, this is the Kitchen Sink-iest spot of all the Kitchen Sink teams this year. The Bengals opened the year among the Super Bowl favorites. They absolutely have to have this one at 0-2.

We hit Stafford's passing yards over with ease last week, so let's go back to the well. Is Stafford a top-three QB in the NFC right now? Is he No. 1? Stafford looks healthy and amazing, and he and rookie Puka Nakua are lighting up defenses, so why should we believe he'll slow down now?

This line is higher than the one a week ago, but still not high enough. Stafford has gone over this number in 18 of 28 games with the Rams (64%), with a few other near misses. In fact, take some of last week's winnings and sprinkle Stafford at +2200 to lead the league in passing yards at DraftKings. He's second in attempts and third in yards, and he'll only get better once Cooper Kupp returns.

Pick: Matthew Stafford Over 252.5 Passing Yards (-115)

For more NFL Week 3 picks, check out Action Network's NFL Week 3: How to Bet Every Game & Every Team.

The One Stat to Know About Rams vs Bengals

Action Network NFL researcher Evan Abrams offers his top betting stat:

Matt Stafford is 4-16 SU and 7-13 ATS as an underdog in night games.

For more NFL Week 3 picks, check out Action Network's NFL Week 3 Betting Trends, Stats, Notes.

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