NFL: Green Bay Packers vs. Pittsburgh Steelers Prediction, Odds, Best Bet

NFL: Green Bay Packers vs. Pittsburgh Steelers Prediction, Odds, Best Bet

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GB @ PIT Odds

The Packers will take on the Steelers in this week's NFL action. Kickoff is set for 8:20 p.m. EDT at Acrisure Stadium in Pittsburgh, Pa. The game will be broadcast live on NBC/Peacock. Here's everything you need to know about Packers vs. Steelers odds, the latest NFL spreads, NFL over/unders and more.

The Packers opened as a -3 point favorite over Steelers. The total is set at over/under 45.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 10/23/25

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Green Bay Packers vs. Pittsburgh Steelers Best Bet

The Steelers are coming into this game with a rest advantage. They played the Cincinnati Bengals on Thursday Night Football last week, while the Packers were involved in a close game against the Cardinals on Sunday.

While the Steelers defense has not been particularly strong this season, they boast one of the best red zone defenses in the NFL allowing touchdowns on opposing red zone trips 47.8% of the time.

The Steelers offense is efficient in the red zone as well, averaging a touchdown on 72% of red zone trips. The Steelers keep this game close, thanks to rest and red zone efficiency.

Green Bay Packers vs. Pittsburgh Steelers Best Bet: Pittsburgh Steelers +3 (-113)

(Pick from Dylan Wilkerson)


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What Time is the Green Bay Packers vs. Pittsburgh Steelers Game?

The Green Bay Packers vs. Pittsburgh Steelers game is at 8:20 PM ET on Sunday, October 26th.

Where is the Green Bay Packers vs. Pittsburgh Steelers Game Being Played?

This game will be played at Acrisure Stadium in Pittsburgh, PA.

How Can I Watch The Green Bay Packers vs. Pittsburgh Steelers?

You can watch Green Bay Packers vs. Pittsburgh Steelers on NBC.

Can the Steelers Beat the Packers?

Of course! The Steelers are only a 3 point underdog so anyone can win.