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Last Updated Jun 22, 2022, 21:16 PM

2022 SAN FRANCISCO 49ERS BETTING PICKS, PREDICTIONS, ODDS

2022 SAN FRANCISCO 49ERS BETTING ODDS, PREDICTIONS, PREVIEW

Best Bet:

2022 SAN FRANCISCO 49ERS SCHEDULE

  • Week 1 - at Chicago (FOX, 1:00 p.m.)
  • Week 2 - vs. Seattle (FOX, 4:05 p.m.)
  • Week 3 - at Denver (NBC, 8:20 p.m.)
  • Week 4 - vs. L.A. Rams (ESPN, 8:15 p.m.)
  • Week 5 - at Carolina (CBS, 4:05 p.m.)
  • Week 6 - at Atlanta (FOX, 1:00 p.m.)
  • Week 7 - vs. Kansas City (FOX, 4:25 p.m.)
  • Week 8 - at L.A. Rams (FOX, 4:25 p.m.)
  • Week 9 - BYE
  • Week 10 - vs. L.A. Chargers (NBC, 8:20 p.m.)
  • Week 11 - vs. Arizona (ESPN, 8:00 p.m.)
  • Week 12 - vs. New Orleans (FOX, 4:25 p.m.)
  • Week 13 - vs. Miami (FOX, 4:05 p.m.)
  • Week 14 - vs. Tampa Bay (FOX, 4:25 p.m.)
  • Week 15 - at Seattle (Prime Video, 8:15 p.m.)
  • Week 16 - vs. Washington (CBS, 4:05 p.m.)
  • Week 17 - at Las Vega (FOX, 4:05 p.m.)
  • Week 18 - vs. Arizona (TBD)

WIN TOTAL ODDS

  • Over 9.5 (-150)
  • Under 9.5 (+120)

SAN FRANCISCO 49ERS ODDS TO WIN NFC WEST

+175

SAN FRANCISCO 49ERS ODDS TO WIN NFC CHAMPIONSHIP

+800

SAN FRANCISCO 49ERS ODDS TO WIN SUPER BOWL 57

+1600

SAN FRANCISCO 49ERS MVP CONTENDERS & ODDS

Trey Lance (QB) +5000

Deebo Samuel (WR) +6000

Jimmy Garoppolo (QB) +10000

Elijah Mitchell (RB) +15000

George Kittle (TE) +20000

Nick Bosa (DE) +25000

SAN FRANCISCO 49ERS TO MAKE PLAYOFFS ODDS

Make Playoff?: Yes (-220) No (+175)

2021 SAN FRANCISCO 49ERS BETTING RESULTS

  • SU: 12-8
  • ATS: 12-8
  • O/U: 6-10-1
  • ATS-Home: 4-4
  • ATS-Road: 5-4
  • ATS-Favorite: 4-5
  • ATS-Underdog: 5-3

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