Last Updated Oct 05, 2022, 7:03 PM

NFL Week 4 Parlay Picks and Predictions

Betting expert Michael Crosson provides his top parlay selections for Week 4 of the NFL season. Odds provided by DraftKings.

ATS Parlay Best Bet

  • Las Vegas Raiders -2.5 (-110) vs. DEN
  • Detroit Lions -3.5 (-110) vs. SEA

Payout: +264

Las Vegas went into Week 1 with sky high expectations, as the Raiders earned the top Wild Card spot in the AFC with a record of 10-7 last year, and this past offseason, they brought in All-Pro WR Devante Adams and head coach Josh McDaniels to help steer the ship. However, things haven’t exactly gone as planned, as the Raiders kicked off the season with consecutive losses to the Chargers, Cardinals, and Titans, with all three of those losses coming by less than a touchdown.

I’ll back Vegas to finally put a win on the board here, as the Raiders still averaged 21.3 PPG on 347 YPG across their trio of losses to open the year; likely presenting an uphill battle for another new-look squad going through some major growing pains in Denver, as the Broncos averaged just 14.3 PPG on 348 YPG in Russell Wilson’s first three games under center.

Detroit isn’t exactly off to a hot start, however, it’s certainly been exciting, as Lions lit up the scoreboard for 31.7 PPG on 409 YPG in their first three contests of the season, which resulted in a pair of highly competitive losses to Philadelphia and Minnesota, and a comfortable 36-27 win over Washington.

I’ll back the Lions to post another comfortable victory here, as the Seahawks’ defense has surrendered 27+ PTS on 385+ YDS in two-of-three matchups to open the year, and I doubt we’ll see the Seahawks’ offense stand toe-to-toe and trade punches with Detroit after averaging just 15.7 PPG on 296 YPG across their bumpy 1-2 start to the season.

ML Parlay Best Bet

  • Arizona Cardinals ML (+105) @ CAR
  • Cleveland Browns ML (-125) @ ATL

Payout: +269

Carolina is off to a lackluster start with Baker Mayfield under center, as the Panthers scored just 20.7 PPG on 276 YPG in their first three matchups of the season, which resulted in a pair of narrow three-point losses to the Browns and Giants, and a tough 22-14 victory over the Saints.

The Cardinals, on the other hand, have been incredibly inconsistent since drafting Kyler Murray with the first-overall pick in the 2019 draft, however, opening the season with matchups against the Chiefs, Raiders, and Rams isn’t exactly a walk in the park, so it’s tough to blame them. I’ll back Arizona here, as the Cardinals still strike me as the much better team in this matchup, and I expect them to handle business against stagnant offenses like Carolina with relative ease.

Atlanta is off to a somewhat inspiring start to the season, as the Falcons opened with a pair of surprisingly competitive losses to superior opponents in the Saints and Rams, and then in Week 3, they finally got over the hump with a tough 27-23 road victory in Seattle.

Cleveland, on the other hand, has really shown off the depth of its roster to open the season, as backup QB Jacoby Brissett has led the Browns’ offense to 28.3 PPG on 379 YPG through their first three contests, which resulted in a pair of wins over the Panthers and Steelers, and a fluky loss to the Jets. So, I’ll back the team with the better roster here, as I’m still not convinced this Falcons squad is any better than the bottom-dwelling squad we’ve seen the last few seasons.

Six-Point Teaser

  • Philadelphia Eagles -0.5 (-6.5) vs. JAX
  • Tennessee Titans +9.5 (+3.5) @ IND

Payout: -120

The Eagles closed last year’s regular season with wins in six of their last eight contests, and it appears they’ve kept that same ball rolling to open this season, as Philly now stands as the lone undefeated squad in the NFC after posting a trio of commanding victories over the Lions, Vikings, and Commanders; highlighted by the Birds’ offense averaging 28.7 PPG on 447 YPG, and defensively, surrendering just 16.7 PPG on 297 YPG in those three contests.

I’ll back the Eagles to win a fourth straight here, as Doug Pederson returns to Philly to face his former squad on Sunday afternoon, and while Pederson's Jaguars have played surprisingly well through the first three weeks of the season, I still think Jacksonville’s no match for this red-hot Eagles squad at Lincoln Financial Field.

Indianapolis has been on quite the rollercoaster to start the season, as the Colts opened with an ugly tie-loss combo against the Texans and Jaguars in Weeks 1 and 2. However, they caught Kansas City sleeping in Week 3, as the Colts escaped with a narrow three-point home victory against the Chiefs despite scoring just 20 PTS on 259 yards of total offense this past Sunday.

The Titans, on the other hand, also posted their first win of the season this past Sunday, as Tennessee opened with a one-point loss to the Giants and a 34-point loss to the Bills before finally getting over the hump with a 24-22 victory over the Raiders in Week 3. I’ll back Tennessee at a teased price here, as I think we’re looking at a pretty even matchup, however, I’d still lean with the Titans after seeing Matt Ryan struggle in his first two divisional matchups against Houston and Jacksonville (60% CMP, 3 TD, 4 INT).

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