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Featured Last Updated Oct 27 2025, 4:50 PM

NFL: Minnesota Vikings vs. Detroit Lions Prediction, Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
NFL: Minnesota Vikings vs. Detroit Lions Prediction, Odds, Best Bet

Featured Image Credit: Junfu Han / USA TODAY NETWORK via Imagn Images

MIN @ DET Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Minnesota Vikings 461 Vikings
+4.5 -110 +5.5 -105 + N/A +5.5 -105 + +5.5 even + N/A +6.5 -110 + N/A +5.5 -105 N/A +8.5 -110  
Detroit Lions 462 Lions
-4.5 -110 -5.5 -115 + N/A -5.5 -115 + -5.5 -121 + N/A -6.5 -110 + N/A -5.5 -115 N/A -8.5 -110  
Minnesota Vikings 461 Vikings
o47.5 -110 o24.5 even + N/A o24.5 even + o24.5 -102 + N/A o24.5 -100 + N/A o24.5 even N/A o47.5 -110  
Detroit Lions 462 Lions
u47.5 -110 u24.5 -120 + N/A u24.5 -120 + u24.5 -121 + N/A u24.5 -120 + N/A u24.5 -120 N/A u47.5 -110  
Minnesota Vikings 461 Vikings
+164 +250 + N/A +235 + +255 + N/A +270 + N/A +240 N/A +360  
Detroit Lions 462 Lions
-198 -320 + N/A -305 + -335 + N/A -370 + N/A -300 N/A -470  
Minnesota Vikings 461 Vikings
+4.5 -110 +2.5 even + N/A +2.5 -108 + N/A N/A +2.5 +106 + N/A +1.5 -105 N/A +8.5 -110  
Detroit Lions 462 Lions
-4.5 -110 -2.5 -120 + N/A -2.5 -112 + N/A N/A -2.5 -128 + N/A -1.5 -125 N/A -8.5 -110  
Minnesota Vikings 461 Vikings
o47.5 -110 o9.5 -120 + N/A o9.5 -120 + N/A N/A o9.5 -118 + N/A o8.5 -140 N/A o47.5 -110  
Detroit Lions 462 Lions
u47.5 -110 u9.5 even + N/A u9.5 even + N/A N/A u9.5 -102 + N/A u8.5 +105 N/A u47.5 -110  
Minnesota Vikings 461 Vikings
+164 +195 + N/A +180 + N/A N/A +210 + N/A +185 N/A +360  
Detroit Lions 462 Lions
-198 -240 + N/A -225 + N/A N/A -265 + N/A -250 N/A -470  
Minnesota Vikings 461 Vikings
+4.5 -110 N/A N/A N/A N/A N/A +3.5 -105 + N/A N/A N/A +8.5 -110  
Detroit Lions 462 Lions
-4.5 -110 N/A N/A N/A N/A N/A -3.5 -115 + N/A N/A N/A -8.5 -110  
Minnesota Vikings 461 Vikings
o47.5 -110 N/A N/A N/A N/A N/A o23.5 -100 + N/A N/A N/A o47.5 -110  
Detroit Lions 462 Lions
u47.5 -110 N/A N/A N/A N/A N/A u23.5 -120 + N/A N/A N/A u47.5 -110  
Minnesota Vikings 461 Vikings
+164 N/A N/A N/A N/A N/A +198 + N/A N/A N/A +360  
Detroit Lions 462 Lions
-198 N/A N/A N/A N/A N/A -250 + N/A N/A N/A -470  
Minnesota Vikings 461 Vikings
+4.5 -110 N/A N/A N/A N/A N/A +3.5 -110 + N/A N/A N/A +8.5 -110  
Detroit Lions 462 Lions
-4.5 -110 N/A N/A N/A N/A N/A -3.5 -110 + N/A N/A N/A -8.5 -110  
Minnesota Vikings 461 Vikings
o47.5 -110 N/A N/A N/A N/A N/A o14.5 -110 + N/A N/A N/A o47.5 -110  
Detroit Lions 462 Lions
u47.5 -110 N/A N/A N/A N/A N/A u14.5 -110 + N/A N/A N/A u47.5 -110  
Minnesota Vikings 461 Vikings
+164 N/A N/A N/A N/A N/A +205 + N/A N/A N/A +360  
Detroit Lions 462 Lions
-198 N/A N/A N/A N/A N/A -265 + N/A N/A N/A -470  
Minnesota Vikings 461 Vikings
+4.5 -110 N/A N/A N/A N/A N/A +1.5 -112 + N/A N/A N/A +8.5 -110  
Detroit Lions 462 Lions
-4.5 -110 N/A N/A N/A N/A N/A -1.5 -108 + N/A N/A N/A -8.5 -110  
Minnesota Vikings 461 Vikings
o47.5 -110 N/A N/A N/A N/A N/A o9.5 -126 + N/A N/A N/A o47.5 -110  
Detroit Lions 462 Lions
u47.5 -110 N/A N/A N/A N/A N/A u9.5 +104 + N/A N/A N/A u47.5 -110  
Minnesota Vikings 461 Vikings
+164 N/A N/A N/A N/A N/A +160 + N/A N/A N/A +360  
Detroit Lions 462 Lions
-198 N/A N/A N/A N/A N/A -205 + N/A N/A N/A -470  
Minnesota Vikings 461 Vikings
+4.5 -110 N/A N/A N/A N/A N/A +1.5 -110 + N/A N/A N/A +8.5 -110  
Detroit Lions 462 Lions
-4.5 -110 N/A N/A N/A N/A N/A -1.5 -110 + N/A N/A N/A -8.5 -110  
Minnesota Vikings 461 Vikings
o47.5 -110 N/A N/A N/A N/A N/A o13.5 -100 + N/A N/A N/A o47.5 -110  
Detroit Lions 462 Lions
u47.5 -110 N/A N/A N/A N/A N/A u13.5 -122 + N/A N/A N/A u47.5 -110  
Minnesota Vikings 461 Vikings
+164 N/A N/A N/A N/A N/A +152 + N/A N/A N/A +360  
Detroit Lions 462 Lions
-198 N/A N/A N/A N/A N/A -188 + N/A N/A N/A -470  

The Vikings will take on the Lions in this week's NFL action. Kickoff is set for 1:00 p.m. EST at Ford Field in Detroit, Mich. The game will be broadcast live on FOX. Here's everything you need to know about Vikings vs. Lions odds, the latest NFL spreads, NFL over/unders and more.

The Lions opened as a -8.5 point favorite over Vikings. The total is set at over/under 47.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 10/27/25

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Minnesota Vikings vs. Detroit Lions Best Bet

Get Carson Wentz off of that field! J.J. McCarthy is slated to be running the Vikings offense for the first time since September 14th. McCarthy was able to get a taste of meaningful NFL action and then was sidelined with an injury. I am confident he takes the field on Sunday, ready to face a divisional rival.

The rest advantage that Detroit has is dampened by the fact that the Vikings have some extra time to prepare given that they played on Thursday Night Football. This is all enough for the Vikings to keep this NFC North matchup close.

Minnesota Vikings vs. Detroit Lions Best Bet: Minnesota Vikings +9 (-110)

(Pick from Dylan Wilkerson)


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What Time is the Minnesota Vikings vs. Detroit Lions Game?

The Minnesota Vikings vs. Detroit Lions game is at 1:00 PM ET on Sunday, November 2nd.

Where is the Minnesota Vikings vs. Detroit Lions Game Being Played?

This game will be played at Ford Field in Detroit, Mich.

How Can I Watch Minnesota Vikings vs. Detroit Lions?

You can watch Minnesota Vikings vs. Detroit Lions on FOX.

Can the Vikings Beat the Lions?

Of course! The Vikings are only a 9 point underdog so anyone can win.

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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