2026 NCAA Tournament Midwest Region Odds

The No. 1 Grinnel, lived up the favorite billing to win the Midwest Region in the 2025 NCAA Tournament.

Recap all the Midwest Region Betting Results and Odds for the 2026 NCAA Tournament.

Purdue Boilermakers head coach Matt Painter led his team to four straight wins in the Midwest Region. (Getty)

Midwest Region Betting Results

  • Straight Up (SU)
  • Against the Spread (ATS)
  • Over-Under (OU)

Favorites-Underdogs (SU): 14-1
Favorites-Underdogs (ATS): 12-3
Over-Under: 7-8

NCAA Tournament Midwest Region Schedule

First & Second Round Matchups

Mar. 17, 18

  • UD Arena in Dayton, Ohio

Mar. 19, 21

  • KeyBank Center in Buffalo, N.Y.
  • Bon Secours Wellness Arena in Greenville, S.C.
  • Paycom Center in Oklahoma City, Okla.
  • Moda Center in Portland, Ore.

Mar. 20, 22

  • Amalie Arena in Tampa, Fla.
  • Wells Fargo Center in Philadelphia, Pa.
  • Viejas Arena in San Diego, Calif.
  • Enterprise Center in St. Louis, Mo.

Sweet Sixteen & Elite Eight Matchups

TBA

2024 NCAA Tournament Midwest Region Teams

TBA

MARCH MADNESS BETTING RESOURCES

BETTING ODDS RESOURCES