CBB: Santa Clara vs. Xavier: Prediction, Odds, Best Bet
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The Santa Clara Broncos (2-0) and Xavier Musketeers (2-0) will face off in College Basketball tonight. Tipoff is set for 8:30 p.m. EST from Cintas Center in Cincinnati, Ohio. The game will broadcast live on Fox Sports 1.
The Xavier Musketeers are favored by -3.5 on the spread, with the over/under set at 155.5 total points. The Musketeers are -192 favorites to win outright on the moneyline, while the Broncos are +160 to pull off the upset.
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Updated on 2/9/26

Santa Clara Broncos vs. Xavier Musketeers Best Bet
I'll take plus money with Santa Clara ML. Even on the road, I view this game as a pick' em, so I'm rolling with the ML.
From a pure talent standpoint, I'd take Santa Clara. Plus, it's still early in the season, and I value teams that have experience playing together. Santa Clara has four starters who were with the program last year — and Xavier has none.
I think Xavier will be among the worst high-major teams in the country — and the Broncos, while they are a WCC team, operate like a high-major program. They have plenty of talent and a proven style that leads to winning.
Santa Clara vs. Xavier Best Bet: Santa Clara ML
(Pick from Sean Paul)
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