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Featured Last Updated Sep 12 2025, 9:51 AM

Bills vs. Jets Week 2 Prediction: Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
Bills vs. Jets Week 2 Prediction: Odds, Best Bet

Buffalo Bills vs. New York Jets Odds, NFL Week 2

Image Credit: Tina MacIntyre-Yee/Democrat and Chronicle / USA TODAY NETWORK via Imagn Images

BUF @ NYJ Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Buffalo Bills 261 Bills
-8.5 -110 -3 -115 + -3.5 -115 + -3.5 -115 + -3 -115 + -3.5 -110 + -3.5 -110 + -2.5 -145 -3.5 -106 + -3.5 -106 -6.5 -115  
New York Jets 262 Jets
+8.5 -110 +3 -105 + +3.5 -105 + +3.5 -105 + +3 -105 + +3.5 -120 + +3.5 -110 + +2.5 +115 +3.5 -117 + +3.5 -117 +6.5 -105  
Buffalo Bills 261 Bills
o44.5 -110 o23.5 -110 + N/A o22.5 -122 + o23.5 -110 + N/A o23.5 -120 + o24.5 +105 o23.5 +102 + o23.5 +102 o46.5 -110  
New York Jets 262 Jets
u44.5 -110 u23.5 -110 + N/A u22.5 +102 + u23.5 -110 + N/A u23.5 -100 + u24.5 -130 u23.5 -127 + u23.5 -127 u46.5 -110  
Buffalo Bills 261 Bills
-380 -200 + N/A -218 + -205 + -240 + -220 + -210 -215 + -215 -310  
New York Jets 262 Jets
+300 +165 + N/A +180 + +170 + +170 + +180 + +175 +170 + +170 +260  
Buffalo Bills 261 Bills
-8.5 -110 -0.5 -115 + -0.5 -110 + -0.5 -105 + -0.5 -115 + -0.5 -115 + -1.5 -100 + -0.5 -110 -1.5 -103 + -1.5 -103 -6.5 -115  
New York Jets 262 Jets
+8.5 -110 +0.5 -105 + +0.5 -115 + +0.5 -115 + +0.5 -115 + +0.5 -115 + +1.5 -122 + +0.5 -120 +1.5 -121 + +1.5 -121 +6.5 -105  
Buffalo Bills 261 Bills
o44.5 -110 o7.5 -110 + N/A o7.5 -110 + o7.5 -115 + o8.5 -120 + o9.5 -108 + o8.5 -145 o9.5 -118 + o9.5 -118 o46.5 -110  
New York Jets 262 Jets
u44.5 -110 u7.5 -110 + N/A u7.5 -110 + u7.5 -115 + u8.5 -110 + u9.5 -112 + u8.5 +110 u9.5 -106 + u9.5 -106 u46.5 -110  
Buffalo Bills 261 Bills
-380 -180 + N/A -185 + -180 + -190 + -188 + -175 -190 + -190 -310  
New York Jets 262 Jets
+300 +150 + N/A +150 + +150 + +140 + +152 + +135 +150 + +150 +260  
Buffalo Bills 261 Bills
-8.5 -110 -3.5 -110 + N/A -3.5 -115 + -3.5 even + N/A -3.5 -100 + N/A -3.5 even + -3.5 even -6.5 -115  
New York Jets 262 Jets
+8.5 -110 +3.5 -110 + N/A +3.5 -105 + +3.5 -120 + N/A +3.5 -120 + N/A +3.5 -124 + +3.5 -124 +6.5 -105  
Buffalo Bills 261 Bills
o44.5 -110 o23.5 -105 + N/A o23.5 -105 + o23.5 -105 + N/A o23.5 -100 + N/A o23.5 -115 + o23.5 -115 o46.5 -110  
New York Jets 262 Jets
u44.5 -110 u23.5 -115 + N/A u23.5 -115 + u23.5 -115 + N/A u23.5 -120 + N/A u23.5 -108 + u23.5 -108 u46.5 -110  
Buffalo Bills 261 Bills
-380 -225 + N/A -225 + N/A N/A -210 + N/A -200 + -200 -310  
New York Jets 262 Jets
+300 +185 + N/A +185 + N/A N/A +172 + N/A +155 + +155 +260  
Buffalo Bills 261 Bills
-8.5 -110 N/A N/A -2.5 -115 + -2.5 -120 + N/A -2.5 -116 + N/A N/A N/A -6.5 -115  
New York Jets 262 Jets
+8.5 -110 N/A N/A +2.5 -105 + +2.5 even + N/A +2.5 -106 + N/A N/A N/A +6.5 -105  
Buffalo Bills 261 Bills
o44.5 -110 o13.5 -110 + N/A o13.5 -110 + o13.5 -115 + N/A o14.5 -102 + N/A N/A N/A o46.5 -110  
New York Jets 262 Jets
u44.5 -110 u13.5 -110 + N/A u13.5 -110 + u13.5 -105 + N/A u14.5 -120 + N/A N/A N/A u46.5 -110  
Buffalo Bills 261 Bills
-380 -185 + N/A -185 + -185 + N/A -188 + N/A N/A N/A -310  
New York Jets 262 Jets
+300 +155 + N/A +154 + +155 + N/A +154 + N/A N/A N/A +260  
Buffalo Bills 261 Bills
-8.5 -110 N/A N/A -1.5 -108 + -1.5 even + N/A -1.5 -102 + N/A N/A N/A -6.5 -115  
New York Jets 262 Jets
+8.5 -110 N/A N/A +1.5 -112 + +1.5 -120 + N/A +1.5 -120 + N/A N/A N/A +6.5 -105  
Buffalo Bills 261 Bills
o44.5 -110 o9.5 -125 + N/A o9.5 -125 + o9.5 -115 + N/A o9.5 -126 + N/A N/A N/A o46.5 -110  
New York Jets 262 Jets
u44.5 -110 u9.5 +105 + N/A u9.5 +105 + u9.5 -105 + N/A u9.5 +104 + N/A N/A N/A u46.5 -110  
Buffalo Bills 261 Bills
-380 -190 + N/A -192 + -190 + N/A -188 + N/A N/A N/A -310  
New York Jets 262 Jets
+300 +160 + N/A +160 + +160 + N/A +148 + N/A N/A N/A +260  
Buffalo Bills 261 Bills
-8.5 -110 -0.5 -130 + N/A -2.5 -108 + -1.5 -105 + N/A -1.5 -100 + N/A N/A N/A -6.5 -115  
New York Jets 262 Jets
+8.5 -110 +0.5 +110 + N/A +2.5 -112 + +1.5 -115 + N/A +1.5 -122 + N/A N/A N/A +6.5 -105  
Buffalo Bills 261 Bills
o44.5 -110 o13.5 -105 + N/A o13.5 -102 + o12.5 -125 + N/A o13.5 -102 + N/A N/A N/A o46.5 -110  
New York Jets 262 Jets
u44.5 -110 u13.5 -115 + N/A u13.5 -118 + u12.5 +105 + N/A u13.5 -120 + N/A N/A N/A u46.5 -110  
Buffalo Bills 261 Bills
-380 -180 + N/A -180 + -170 + N/A -164 + N/A N/A N/A -310  
New York Jets 262 Jets
+300 +150 + N/A +154 + +143 + N/A +134 + N/A N/A N/A +260  

The Bills will take on the Jets in this week's NFL action. Kickoff is set for 1:00 p.m. EDT at MetLife Stadium in East Rutherford, N.J. The game will be broadcast live on CBS. Here's everything you need to know about Bills vs. Jets odds, the latest NFL spreads, NFL over/unders and more.

The Bills opened as a -6.5 point favorite over Jets. The total is set at over/under 46.5 total points scored by both teams combined.

Be sure to check out the latest NFL Odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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Buffalo Bills vs. New York Jets Best Bet

The Jets' offense looked like a completely revived unit in their season debut against one of the best defenses in the league last season. Although they could not secure the win, the offense was humming, which is a nice change of pace if you are a New York Jets fan.

Justin Fields averaged 0.4 EPA per dropback and 0.33 EPA per rush attempt, having success in just about every play type and situation. The Bills, on the other hand, played on Sunday night and were involved in a dramatic finish against the Baltimore Ravens.

I am going to take the divisional underdog, who showed some promise in their season debut against a historically strong defense, to keep it close in this matchup.

Buffalo Bills vs. New York Jets Best Bet: New York Jets +6.5 (-108)

(Pick via Dylan Wilkerson)


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What Time is the Buffalo Bills vs. New York Jets Game?

The Buffalo Bills will take on the New York Jets at 1:00 ET on Sunday, September 14th.

Where is the Buffalo Bills vs. New York Jets Game Being Played?

This game is going to be played at MetLife Stadium in East Rutherford, N.J.

How Can I Watch the Buffalo Bills vs. New York Jets?

You can watch The Bills vs. The Jets on CBS.

Can The Jets Beat The Bills?

The Jets can certainly beat Buffalo. Being a divisional underdog is a great spot, especially at home.

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 2 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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