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Featured Last Updated Nov 7 2025, 7:42 AM

NFL: Patriots vs. Buccaneers, Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
9 minute read
NFL: Patriots vs. Buccaneers, Prediction, Odds, Best Bet

Featured Image Credit: Brian Fluharty via Imagn Images

NE @ TB Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
New England Patriots 263 Patriots
+4.5 -110 +0.5 even + +0.5 -110 + +0.5 -105 + +1.5 -125 + +0.5 -120 + +1.5 -120 + +0.5 -110 + +1.5 -120 +1.5 -127 + +2.5 -110  
Tampa Bay Buccaneers 264 Buccaneers
-4.5 -110 -0.5 -120 + -0.5 -118 + -0.5 -115 + -1.5 even + -0.5 -110 + -1.5 -100 + -0.5 -110 + -1.5 even -1.5 +102 + -2.5 -110  
New England Patriots 263 Patriots
o46.5 -110 o24 -115 + o24.5 -102 + o24.5 even + o24 -113 + N/A o24.5 +110 + o23.5 -120 + o24.5 even o23.5 -120 + o48.5 -115  
Tampa Bay Buccaneers 264 Buccaneers
u46.5 -110 u24 -105 + u24.5 -118 + u24.5 -120 + u24 -108 + N/A u24.5 -130 + u23.5 even + u24.5 -120 u23.5 -105 + u48.5 -105  
New England Patriots 263 Patriots
+170 +115 + +115 + +114 + +115 + even + +106 + N/A +115 +108 + +124  
Tampa Bay Buccaneers 264 Buccaneers
-205 -135 + -140 + -135 + -135 + -130 + -128 + N/A -140 -136 + -148  
New England Patriots 263 Patriots
+4.5 -110 +0.5 -155 + +0.5 -155 + +0.5 -148 + N/A +0.5 -145 +1.5 -160 + +0.5 -150 + +1.5 -165 +1.5 -165 + +2.5 -110  
Tampa Bay Buccaneers 264 Buccaneers
-4.5 -110 -0.5 +130 + -0.5 +120 + -0.5 +124 + N/A -0.5 +115 -1.5 +130 + -0.5 +125 + -1.5 +120 -1.5 +132 + -2.5 -110  
New England Patriots 263 Patriots
o46.5 -110 o9.5 -115 + o9.5 -115 + o9.5 -115 + N/A N/A o9.5 -124 + o9.5 -120 + o8.5 -135 o9.5 -120 + o48.5 -115  
Tampa Bay Buccaneers 264 Buccaneers
u46.5 -110 u9.5 -105 + u9.5 -110 + u9.5 -105 + N/A N/A u9.5 +102 + u9.5 even + u8.5 even u9.5 -105 + u48.5 -105  
New England Patriots 263 Patriots
+170 +105 + +105 + +110 + N/A +105 +106 + N/A even +105 + +124  
Tampa Bay Buccaneers 264 Buccaneers
-205 -125 + -135 + -130 + N/A -135 -130 + N/A -130 -130 + -148  
New England Patriots 263 Patriots
+4.5 -110 +0.5 -110 + N/A +1.5 -130 + N/A N/A +1.5 -135 + N/A N/A +1.5 -134 + +2.5 -110  
Tampa Bay Buccaneers 264 Buccaneers
-4.5 -110 -0.5 -110 + N/A -1.5 +110 + N/A N/A -1.5 +115 + N/A N/A -1.5 +108 + -2.5 -110  
New England Patriots 263 Patriots
o46.5 -110 o23.5 -110 + N/A o23.5 -118 + N/A N/A o23.5 -100 + o23.5 -120 + N/A o23.5 -124 + o48.5 -115  
Tampa Bay Buccaneers 264 Buccaneers
u46.5 -110 u23.5 -110 + N/A u23.5 -102 + N/A N/A u23.5 -120 + u23.5 -110 + N/A u23.5 even + u48.5 -105  
New England Patriots 263 Patriots
+170 -105 + N/A +105 + N/A N/A +106 + N/A N/A +102 + +124  
Tampa Bay Buccaneers 264 Buccaneers
-205 -115 + N/A -125 + N/A N/A -124 + N/A N/A -127 + -148  
New England Patriots 263 Patriots
+4.5 -110 N/A N/A +0.5 -120 + N/A N/A +1.5 -140 + +0.5 -130 + N/A N/A +2.5 -110  
Tampa Bay Buccaneers 264 Buccaneers
-4.5 -110 N/A N/A -0.5 even + N/A N/A -1.5 +118 + -0.5 even + N/A N/A -2.5 -110  
New England Patriots 263 Patriots
o46.5 -110 o14 -110 + N/A o14.5 -108 + N/A N/A o14.5 -104 + o14.5 -110 + N/A N/A o48.5 -115  
Tampa Bay Buccaneers 264 Buccaneers
u46.5 -110 u14 -110 + N/A u14.5 -112 + N/A N/A u14.5 -118 + u14.5 -120 + N/A N/A u48.5 -105  
New England Patriots 263 Patriots
+170 even + N/A +110 + N/A N/A +106 + N/A N/A N/A +124  
Tampa Bay Buccaneers 264 Buccaneers
-205 -120 + N/A -130 + N/A N/A -130 + N/A N/A N/A -148  
New England Patriots 263 Patriots
+4.5 -110 N/A N/A +0.5 -142 + N/A N/A +1.5 -166 + +0.5 -150 + N/A N/A +2.5 -110  
Tampa Bay Buccaneers 264 Buccaneers
-4.5 -110 N/A N/A -0.5 +120 + N/A N/A -1.5 +136 + -0.5 +115 + N/A N/A -2.5 -110  
New England Patriots 263 Patriots
o46.5 -110 o9.5 -130 + N/A o9.5 -130 + N/A N/A o9.5 -120 + o9.5 -130 + N/A N/A o48.5 -115  
Tampa Bay Buccaneers 264 Buccaneers
u46.5 -110 u9.5 +110 + N/A u9.5 +110 + N/A N/A u9.5 -102 + u9.5 even + N/A N/A u48.5 -105  
New England Patriots 263 Patriots
+170 even + N/A +105 + N/A N/A +104 + N/A N/A N/A +124  
Tampa Bay Buccaneers 264 Buccaneers
-205 -120 + N/A -125 + N/A N/A -128 + N/A N/A N/A -148  
New England Patriots 263 Patriots
+4.5 -110 +0.5 -130 + N/A +0.5 -130 + N/A N/A +1.5 -162 + +0.5 -130 + N/A N/A +2.5 -110  
Tampa Bay Buccaneers 264 Buccaneers
-4.5 -110 -0.5 +110 + N/A -0.5 +110 + N/A N/A -1.5 +134 + -0.5 even + N/A N/A -2.5 -110  
New England Patriots 263 Patriots
o46.5 -110 o13.5 -105 + N/A o13.5 -112 + N/A N/A o13.5 -102 + o13.5 -120 + N/A N/A o48.5 -115  
Tampa Bay Buccaneers 264 Buccaneers
u46.5 -110 u13.5 -115 + N/A u13.5 -108 + N/A N/A u13.5 -118 + u13.5 -110 + N/A N/A u48.5 -105  
New England Patriots 263 Patriots
+170 -105 + N/A -102 + N/A N/A -105 + N/A N/A N/A +124  
Tampa Bay Buccaneers 264 Buccaneers
-205 -115 + N/A -118 + N/A N/A -115 + N/A N/A N/A -148  

The Patriots will take on the Buccaneers in this week's NFL action. Kickoff is set for 1:00 p.m. EST at Raymond James Stadium in Tampa, Fla. The game will be broadcast live on CBS. Here's everything you need to know about Patriots vs. Buccaneers odds, the latest NFL spreads, NFL over/unders and more.

The Buccaneers opened as a -2.5 point favorite over Patriots. The total is set at over/under 48.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 11/7/25

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New England Patriots vs. Tampa Bay Buccaneers Best Bet

We've got a slugfest on our hands between two excellent defenses. New England and Tampa Bay rank fourth and fifth in DVOA against the run, respectively, and we know the Patriots' offense is designed around the run with the fourth-highest run play rate in the league.

Now, the Buccaneers do love to throw — and the Patriots have struggled to stop the pass — but New England's allowed very few passing plays this season as the offense has taken control of the game early, and the defense has forced opposing quarterbacks into long throws on passing downs.

We spoke about it last week, but Drake Maye has been tremendous under pressure. He grades out as the 10th-best quarterback against the blitz according to PFF, and Tampa Bay runs a blitz on 38.1% of snaps, the fifth-highest in the league.

That could be a deciding factor here as we look to find an edge in a game that's hard to call, but another deciding factor is certainly going to be how well New England's defense fares. It's had the easiest strength of schedule in the NFL, and it seems it's only going to remain easy with Tampa Bay ranking 28th in rushing DVOA and just 19th through the air.

The Buccaneers are just the 15th-best scoring offense in football and 19th in yards per play, and critically they've been one of the worst teams on third and fourth down, an area where the Patriots rank in the top five defensively.

Patriots vs. Buccaneers Best Bet: Patriots +2.5

(Pick from Kenny Ducey)

Looking for more best bets? Check out our free NFL picks and our premium subscription for the best picks!

What Time is the New England Patriots vs. Tampa Bay Buccaneers Game?

The New England Patriots vs. Tampa Bay Buccaneers game is at 1:00 PM ET on Sunday, November 9th.

Where is the New England Patriots vs. Tampa Bay Buccaneers Game Being Played?

This game will be played at Raymond James Stadium in Tampa Bay, Florida.

How Can I Watch Patriots vs. Bucs?

You can watch Patriots vs. Buccaneers on CBS.

Can the Patriots Beat the Buccaneers?

Yes, the Pats are just 2.5-point underdogs heading into this one.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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