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Featured Last Updated Sep 12 2025, 11:07 AM

NFL: Rams vs. Titans, Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
NFL: Rams vs. Titans, Prediction, Odds, Best Bet

Featured Image Credit: Isaiah J. Downing via Imagn Images

LA @ TEN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Los Angeles Rams 259 Rams
-4.5 -110 -3 -115 + -2.5 -115 + -3.5 even + -3 -108 + -3.5 -105 + -3.5 -100 + -2.5 -130 -2.5 -129 + -2.5 -129 -5.5 -108  
Tennessee Titans 260 Titans
+4.5 -110 +3 -105 + +2.5 -105 + +3.5 -120 + +3 -111 + +3.5 -125 + +3.5 -120 + +2.5 +105 +2.5 +104 + +2.5 +104 +5.5 -112  
Los Angeles Rams 259 Rams
o45.5 -110 o20.5 -110 + N/A o20.5 -108 + o20.5 -119 + N/A o20.5 -110 + o20.5 -110 o20.5 -117 + o20.5 -117 o41.5 -108  
Tennessee Titans 260 Titans
u45.5 -110 u20.5 -110 + N/A u20.5 -112 + u20.5 even + N/A u20.5 -110 + u20.5 -110 u20.5 -107 + u20.5 -107 u41.5 -112  
Los Angeles Rams 259 Rams
-205 -205 + N/A -198 + -190 + -220 + -194 + -190 -195 + -195 -225  
Tennessee Titans 260 Titans
+170 +165 + N/A +164 + +158 + +160 + +158 + +160 +155 + +155 +190  
Los Angeles Rams 259 Rams
-4.5 -110 -0.5 even + -0.5 -102 + -0.5 even + N/A -0.5 -105 + -1.5 +112 + -0.5 -105 -1.5 +108 + -1.5 +108 -5.5 -108  
Tennessee Titans 260 Titans
+4.5 -110 +0.5 -120 + +0.5 -125 + +0.5 -120 + N/A +0.5 -125 + +1.5 -136 + +0.5 -125 +1.5 -136 + +1.5 -136 +5.5 -112  
Los Angeles Rams 259 Rams
o45.5 -110 o7.5 +115 + N/A o7.5 +110 + N/A o7.5 +105 + o7.5 +114 + o8.5 +110 o7.5 -104 + o7.5 -104 o41.5 -108  
Tennessee Titans 260 Titans
u45.5 -110 u7.5 -135 + N/A u7.5 -130 + N/A u7.5 -135 + u7.5 -138 + u8.5 -145 u7.5 -121 + u7.5 -121 u41.5 -112  
Los Angeles Rams 259 Rams
-205 -170 + N/A -185 + -160 + -190 + -168 + -190 -162 + -162 -225  
Tennessee Titans 260 Titans
+170 +145 + N/A +154 + +130 + +140 + +136 + +145 +130 + +130 +190  
Los Angeles Rams 259 Rams
-4.5 -110 -2.5 -115 + N/A -2.5 -118 + -2.5 -120 + N/A -3.5 +105 + N/A -2.5 -129 + -2.5 -129 -5.5 -108  
Tennessee Titans 260 Titans
+4.5 -110 +2.5 -105 + N/A +2.5 -102 + +2.5 even + N/A +3.5 -125 + N/A +2.5 +104 + +2.5 +104 +5.5 -112  
Los Angeles Rams 259 Rams
o45.5 -110 o20.5 even + N/A o19.5 -115 + o19.5 -125 + N/A o20.5 -105 + N/A o19.5 -127 + o19.5 -127 o41.5 -108  
Tennessee Titans 260 Titans
u45.5 -110 u20.5 -120 + N/A u19.5 -105 + u19.5 +105 + N/A u20.5 -115 + N/A u19.5 +102 + u19.5 +102 u41.5 -112  
Los Angeles Rams 259 Rams
-205 -180 + N/A -175 + N/A N/A -196 + N/A -190 + -190 -225  
Tennessee Titans 260 Titans
+170 +150 + N/A +150 + N/A N/A +164 + N/A +150 + +150 +190  
Los Angeles Rams 259 Rams
-4.5 -110 N/A N/A -1.5 -110 + -2.5 -110 + N/A -2.5 -110 + N/A N/A N/A -5.5 -108  
Tennessee Titans 260 Titans
+4.5 -110 N/A N/A +1.5 -110 + +2.5 -110 + N/A +2.5 -110 + N/A N/A N/A +5.5 -112  
Los Angeles Rams 259 Rams
o45.5 -110 o12.5 -135 + N/A o12.5 -135 + o13.5 +110 + N/A o13.5 +110 + N/A N/A N/A o41.5 -108  
Tennessee Titans 260 Titans
u45.5 -110 u12.5 +115 + N/A u12.5 +114 + u13.5 -130 + N/A u13.5 -134 + N/A N/A N/A u41.5 -112  
Los Angeles Rams 259 Rams
-205 -155 + N/A -162 + -175 + N/A -176 + N/A N/A N/A -225  
Tennessee Titans 260 Titans
+170 +130 + N/A +136 + +148 + N/A +142 + N/A N/A N/A +190  
Los Angeles Rams 259 Rams
-4.5 -110 N/A N/A -0.5 +102 + -1.5 even + N/A -1.5 -104 + N/A N/A N/A -5.5 -108  
Tennessee Titans 260 Titans
+4.5 -110 N/A N/A +0.5 -122 + +1.5 -120 + N/A +1.5 -118 + N/A N/A N/A +5.5 -112  
Los Angeles Rams 259 Rams
o45.5 -110 o7.5 -105 + N/A o7.5 -102 + o8.5 -110 + N/A o8.5 -110 + N/A N/A N/A o41.5 -108  
Tennessee Titans 260 Titans
u45.5 -110 u7.5 -115 + N/A u7.5 -118 + u8.5 -110 + N/A u8.5 -110 + N/A N/A N/A u41.5 -112  
Los Angeles Rams 259 Rams
-205 -155 + N/A -162 + -178 + N/A -188 + N/A N/A N/A -225  
Tennessee Titans 260 Titans
+170 +130 + N/A +136 + +150 + N/A +152 + N/A N/A N/A +190  
Los Angeles Rams 259 Rams
-4.5 -110 -0.5 -110 + N/A -0.5 -115 + -1.5 +105 + N/A -1.5 +102 + N/A N/A N/A -5.5 -108  
Tennessee Titans 260 Titans
+4.5 -110 +0.5 -110 + N/A +0.5 -105 + +1.5 -125 + N/A +1.5 -124 + N/A N/A N/A +5.5 -112  
Los Angeles Rams 259 Rams
o45.5 -110 o10.5 -105 + N/A o10.5 +102 + o10.5 -105 + N/A o10.5 -110 + N/A N/A N/A o41.5 -108  
Tennessee Titans 260 Titans
u45.5 -110 u10.5 -115 + N/A u10.5 -120 + u10.5 -115 + N/A u10.5 -110 + N/A N/A N/A u41.5 -112  
Los Angeles Rams 259 Rams
-205 -155 + N/A -162 + -170 + N/A -162 + N/A N/A N/A -225  
Tennessee Titans 260 Titans
+170 +130 + N/A +136 + +140 + N/A +132 + N/A N/A N/A +190  

The Rams will take on the Titans in this week's NFL action. Kickoff is set for 1:00 p.m. EDT at Nissan Stadium in Nashville, Tenn. The game will be broadcast live on CBS. Here's everything you need to know about Rams vs. Titans odds, the latest NFL spreads, NFL over/unders and more.

The Rams opened as a -5.5 point favorite over Titans. The total is set at over/under 41.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

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Los Angeles Rams vs. Tennessee Titans Best Bet

I didn’t think we’d see much on offense from the Rams in Week 1; I was more or less impressed by Sean McVay’s group.

They only turned the ball over once, on a fumble, and Matthew Stafford posted a 109.1 passer rating after sitting out all of camp and the preseason with an injury. With that said, L.A. averaged just 2.9 yards per carry and failed to come up with explosive plays through the air.

You have to give them credit for throwing on one of the best secondaries in football, and similarly this Rams defense – which came into the season with many questions – excelled while the front seven looked a bit weak against the run.

The good news is that the Titans are unlikely to score much, and while the Broncos struggled to pull away in Week 1, they still have a somewhat one-dimensional offense with Bo Nix still growing under center. The Rams are easy to love.

Rams vs. Titans Best Bet: Rams -5.5

(Pick from Kenny Ducey)

Looking for more best bets? Check out our free NFL picks and our premium subscription for the best picks!

What Time is the Los Angeles Rams vs. Tennessee Titans Game?

The Los Angeles Rams will take on the Tennessee Titans at 1:00 ET on Sunday, September 14th.

Where is the Los Angeles Rams vs. Tennessee Titans Game Being Played?

This game is going to be played at Nissan Stadium in Nashville, TN.

How Can I Watch Rams vs. Titans?

You can watch Rams vs. Titans on CBS.

Can the Titans Beat the Rams?

The Titans nearly pulled off the biggest upset of week one, falling just short of beating the Denver Broncos. The Titans will look to finish off the job this upcoming Sunday.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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