Sign Up Subscribe
Featured Last Updated Sep 19 2025, 12:07 PM

NFL: Steelers vs. Patriots, Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
NFL: Steelers vs. Patriots, Prediction, Odds, Best Bet

Featured Image Credit: Nathan Ray Seebeck via Imagn Images

PIT @ NE Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Pittsburgh Steelers 463 Steelers
+1.5 -110 -0.5 -105 + -0.5 -105 + -0.5 -102 + -0.5 even + -0.5 -105 + -1.5 +115 + -0.5 even -1.5 +112 + -1.5 +112 -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 +0.5 -115 + +0.5 -115 + +0.5 -118 + +0.5 -120 + +0.5 -125 + +1.5 -135 + +0.5 -120 +1.5 -137 + +1.5 -137 +1.5 -105  
Pittsburgh Steelers 463 Steelers
o43.5 -110 o21.5 -120 + N/A o22.5 -110 + o21.5 -120 + N/A o22.5 -110 + o22.5 -120 o22.5 -124 + o22.5 -124 o44.5 -112  
New England Patriots 464 Patriots
u43.5 -110 u21.5 even + N/A u22.5 -110 + u21.5 even + N/A u22.5 -110 + u22.5 even u22.5 even + u22.5 even u44.5 -108  
Pittsburgh Steelers 463 Steelers
+102 -120 + N/A -120 + -120 + -125 + -118 + -120 -121 + -121 -125  
New England Patriots 464 Patriots
-122 even + N/A even + even + -105 + -102 + even -103 + -103 +105  
Pittsburgh Steelers 463 Steelers
+1.5 -110 -0.5 +135 + -0.5 +130 + -0.5 +130 + -0.5 +130 + -0.5 +130 + -1.5 +142 + -0.5 +125 -1.5 +143 + -1.5 +143 -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 +0.5 -160 + +0.5 -165 + +0.5 -155 + +0.5 -160 + +0.5 -170 + +1.5 -174 + +0.5 -170 +1.5 -180 + +1.5 -180 +1.5 -105  
Pittsburgh Steelers 463 Steelers
o43.5 -110 o7.5 +105 + N/A o7.5 +105 + o7.5 even + o7.5 even + o7.5 +102 + o8.5 -140 o7.5 -109 + o7.5 -109 o44.5 -112  
New England Patriots 464 Patriots
u43.5 -110 u7.5 -125 + N/A u7.5 -125 + u7.5 -130 + u7.5 -130 + u7.5 -124 + u8.5 +105 u7.5 -114 + u7.5 -114 u44.5 -108  
Pittsburgh Steelers 463 Steelers
+102 -120 + N/A -122 + -130 + -125 + -118 + -115 -118 + -118 -125  
New England Patriots 464 Patriots
-122 even + N/A +102 + even + -105 + -104 + -115 -105 + -105 +105  
Pittsburgh Steelers 463 Steelers
+1.5 -110 N/A N/A -0.5 +110 + -0.5 +105 + N/A -1.5 +124 + N/A N/A N/A -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 N/A N/A +0.5 -130 + +0.5 -125 + N/A +1.5 -152 + N/A N/A N/A +1.5 -105  
Pittsburgh Steelers 463 Steelers
o43.5 -110 o13 -115 + N/A o13.5 -105 + o13.5 -105 + N/A o13.5 -104 + N/A N/A N/A o44.5 -112  
New England Patriots 464 Patriots
u43.5 -110 u13 -105 + N/A u13.5 -115 + u13.5 -115 + N/A u13.5 -116 + N/A N/A N/A u44.5 -108  
Pittsburgh Steelers 463 Steelers
+102 -125 + N/A -118 + -125 + N/A -118 + N/A N/A N/A -125  
New England Patriots 464 Patriots
-122 +105 + N/A -102 + +105 + N/A -104 + N/A N/A N/A +105  
Pittsburgh Steelers 463 Steelers
+1.5 -110 N/A N/A -0.5 +124 + -0.5 +125 + N/A -1.5 +144 + N/A N/A N/A -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 N/A N/A +0.5 -148 + +0.5 -145 + N/A +1.5 -178 + N/A N/A N/A +1.5 -105  
Pittsburgh Steelers 463 Steelers
o43.5 -110 o9.5 -115 + N/A o9.5 -108 + o9.5 -110 + N/A o9.5 -108 + N/A N/A N/A o44.5 -112  
New England Patriots 464 Patriots
u43.5 -110 u9.5 -105 + N/A u9.5 -112 + u9.5 -110 + N/A u9.5 -112 + N/A N/A N/A u44.5 -108  
Pittsburgh Steelers 463 Steelers
+102 -120 + N/A -125 + -120 + N/A -115 + N/A N/A N/A -125  
New England Patriots 464 Patriots
-122 even + N/A +105 + even + N/A -105 + N/A N/A N/A +105  
Pittsburgh Steelers 463 Steelers
+1.5 -110 -0.5 +120 + N/A -0.5 +114 + -0.5 +110 + N/A -1.5 +132 + N/A N/A N/A -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 +0.5 -140 + N/A +0.5 -135 + +0.5 -130 + N/A +1.5 -162 + N/A N/A N/A +1.5 -105  
Pittsburgh Steelers 463 Steelers
o43.5 -110 o13 -105 + N/A o12.5 -122 + o12.5 -120 + N/A o12.5 -110 + N/A N/A N/A o44.5 -112  
New England Patriots 464 Patriots
u43.5 -110 u13 -115 + N/A u12.5 +102 + u12.5 even + N/A u12.5 -110 + N/A N/A N/A u44.5 -108  
Pittsburgh Steelers 463 Steelers
+102 -115 + N/A -118 + -120 + N/A -118 + N/A N/A N/A -125  
New England Patriots 464 Patriots
-122 -105 + N/A -102 + even + N/A -104 + N/A N/A N/A +105  
Pittsburgh Steelers 463 Steelers
+1.5 -110 -0.5 even + N/A N/A -0.5 even N/A -1.5 +120 + N/A -1.5 +112 + -1.5 +112 -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 +0.5 -120 + N/A N/A +0.5 -120 N/A +1.5 -140 + N/A +1.5 -139 + +1.5 -139 +1.5 -105  
Pittsburgh Steelers 463 Steelers
o43.5 -110 o21.5 even + N/A N/A o22.5 -105 N/A o21.5 -110 + N/A o21.5 -108 + o21.5 -108 o44.5 -112  
New England Patriots 464 Patriots
u43.5 -110 u21.5 -120 + N/A N/A u22.5 -115 N/A u21.5 -110 + N/A u21.5 -114 + u21.5 -114 u44.5 -108  
Pittsburgh Steelers 463 Steelers
+102 -120 + N/A N/A N/A N/A -116 + N/A -120 + -120 -125  
New England Patriots 464 Patriots
-122 even + N/A N/A N/A N/A -100 + N/A -105 + -105 +105  

The Steelers will take on the Patriots in this week's NFL action. Kickoff is set for 1:00 p.m. EDT at Gillette Stadium in Foxborough, Mass. The game will be broadcast live on CBS. Here's everything you need to know about Steelers vs. Patriots odds, the latest NFL spreads, NFL over/unders and more.

The Steelers opened as a -1.5 point favorite over Patriots. The total is set at over/under 44.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 9/19/25

bet365
Bet $5, Get $200 in Bonus Bets Win or Lose!
Bonus Code
VIBONUS
Claim $200
New customers only, 21+ (18+ in KY). Gambling Problem? Call 1-800-GAMBLER. Available in AZ, CO, IA, IL, IN, KS, KY, LA, MD, NC, NJ, OH, PA, TN, VA only. Bet $5 and Get $200 in Bonus Bets at bet365. Registration required. Minimum $10 deposit required. Minimum odds -500 of greater. Bonus Bets wager excluded from returns. T&Cs, time limits and exclusions apply.

Pittsburgh Steelers vs. New England Patriots Best Bet

There may be some value on the rush attempts prop for Jaylen Warren.

THE BLITZ is projecting him to record 17.67 rush attempts, and the oddsmakers are implying 14.17. The model believes there is a 74% chance he records at least 12.5 rush attempts, so there is value on the over at -130.

Steelers vs. Patriots Best Bet: Jaylen Warren Over 12.5 Rush Attempts

(Pick from Derek Carty)

Looking for more best bets? Check out our free NFL picks and our premium subscription for the best picks!

What Time is the Pittsburgh Steelers vs. New England Patriots Game?

The Pittsburgh Steelers vs. New England Patriots at 1:00 ET on Sunday, September 21st.

Where is the Pittsburgh Steelers vs. New England Patriots Game Being Played?

This game will be played at Gillette Stadium in Foxborough, MA.

How Can I Watch Patriots vs. Steelers?

You can watch Patriots vs. Steelers on CBS.

Can the Patriots Beat the Steelers?

Yes, with a spread as small as 1.5, the Patriots are slated as basically a pick 'em against the Steelers.

Featured News

Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
•