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NFL: Steelers vs. Patriots, Prediction, Odds, Best Bet

Derek Mountain
Derek Mountain Sports Betting Expert
8 minute read
NFL: Steelers vs. Patriots, Prediction, Odds, Best Bet

Featured Image Credit: Nathan Ray Seebeck via Imagn Images

PIT @ NE Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Final
Pittsburgh Steelers 463 Steelers
+1.5 -110 -0.5 +110 +0.5 -140 +0.5 -115 -0.5 +110 +1.5 -125 -6.5 -125 -1.5 +120 -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 +0.5 -130 -0.5 +105 -0.5 -115 +0.5 -130 -1.5 +105 +6.5 -105 +1.5 -150 +1.5 -115  
Final
Pittsburgh Steelers 463 Steelers
o43.5 -110 o21.5 -115 N/A o20.5 -120 o21.5 -110 o22.5 -100 o22.5 -140 o22.5 -112 o44.5 -108  
New England Patriots 464 Patriots
u43.5 -110 u21.5 -105 N/A u20.5 -110 u21.5 -110 u22.5 -120 u22.5 +105 u22.5 -112 u44.5 -120  
Final
Pittsburgh Steelers 463 Steelers
+102 -110 N/A +105 -110 +106 -500 -113 -130  
New England Patriots 464 Patriots
-122 -110 N/A -135 -110 -128 +330 -110 even  
Final
Pittsburgh Steelers 463 Steelers
+1.5 -110 -0.5 +135 -0.5 +140 +0.5 -142 -0.5 +130 +1.5 -144 -6.5 -255 -1.5 +148 -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 +0.5 -160 +0.5 -185 -0.5 +110 +0.5 -160 -1.5 +118 +6.5 +175 +1.5 -186 +1.5 -115  
Final
Pittsburgh Steelers 463 Steelers
o43.5 -110 o7.5 -105 N/A o7.5 -105 o7.5 even o7.5 +104 o8.5 -125 o7.5 -103 o44.5 -108  
New England Patriots 464 Patriots
u43.5 -110 u7.5 -115 N/A u7.5 -122 u7.5 -130 u7.5 -126 u8.5 -105 u7.5 -121 u44.5 -120  
Final
Pittsburgh Steelers 463 Steelers
+102 -120 N/A +115 -115 +122 -10000 -113 -130  
New England Patriots 464 Patriots
-122 even N/A -148 -115 -150 +3500 -110 even  
Final
Pittsburgh Steelers 463 Steelers
+1.5 -110 -0.5 even N/A -2.5 -110 -0.5 even -1.5 -110 -0.5 even -1.5 +120 -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 +0.5 -120 N/A +2.5 -120 +0.5 -120 +1.5 -110 +0.5 -135 +1.5 -148 +1.5 -115  
Final
Pittsburgh Steelers 463 Steelers
o43.5 -110 o21.5 -110 N/A o22.5 -115 o22.5 -105 o21.5 -115 o22.5 -125 o22.5 -108 o44.5 -108  
New England Patriots 464 Patriots
u43.5 -110 u21.5 -110 N/A u22.5 -115 u22.5 -115 u21.5 -105 u22.5 -105 u22.5 -115 u44.5 -120  
Final
Pittsburgh Steelers 463 Steelers
+102 -120 N/A -162 N/A -144 -115 -113 -130  
New England Patriots 464 Patriots
-122 even N/A +126 N/A +122 -115 -110 even  
Final
Pittsburgh Steelers 463 Steelers
+1.5 -110 N/A N/A -0.5 +110 -0.5 +105 -1.5 +130 -0.5 +105 N/A -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 N/A N/A +0.5 -142 +0.5 -125 +1.5 -154 +0.5 -140 N/A +1.5 -115  
Final
Pittsburgh Steelers 463 Steelers
o43.5 -110 o13 -110 N/A o12.5 -130 o13.5 -105 o20.5 -112 o12.5 -155 N/A o44.5 -108  
New England Patriots 464 Patriots
u43.5 -110 u13 -110 N/A u12.5 even u13.5 -115 u20.5 -118 u12.5 +115 N/A u44.5 -120  
Final
Pittsburgh Steelers 463 Steelers
+102 -110 N/A -115 -125 -114 -120 N/A -130  
New England Patriots 464 Patriots
-122 -110 N/A -115 +105 -106 -110 N/A even  
Final
Pittsburgh Steelers 463 Steelers
+1.5 -110 N/A N/A -0.5 -115 -0.5 +125 -1.5 +106 -0.5 even N/A -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 N/A N/A +0.5 -115 +0.5 -145 +1.5 -128 +0.5 -135 N/A +1.5 -115  
Final
Pittsburgh Steelers 463 Steelers
o43.5 -110 o9.5 -120 N/A o9.5 -118 o9.5 -110 o2.5 -122 o8.5 -150 N/A o44.5 -108  
New England Patriots 464 Patriots
u43.5 -110 u9.5 even N/A u9.5 -110 u9.5 -110 u2.5 -110 u8.5 +110 N/A u44.5 -120  
Final
Pittsburgh Steelers 463 Steelers
+102 -110 N/A -175 -120 -170 -160 N/A -130  
New England Patriots 464 Patriots
-122 -110 N/A +135 even +138 +120 N/A even  
Final
Pittsburgh Steelers 463 Steelers
+1.5 -110 +0.5 -150 N/A -0.5 +105 -0.5 +110 -1.5 +130 +1.5 -140 N/A -1.5 -115  
New England Patriots 464 Patriots
-1.5 -110 -0.5 +125 N/A +0.5 -135 +0.5 -130 +1.5 -162 -1.5 +105 N/A +1.5 -115  
Final
Pittsburgh Steelers 463 Steelers
o43.5 -110 o13 -110 N/A o12.5 -130 o12.5 -120 o12.5 -110 o12.5 -135 N/A o44.5 -108  
New England Patriots 464 Patriots
u43.5 -110 u13 -110 N/A u12.5 even u12.5 even u12.5 -108 u12.5 even N/A u44.5 -120  
Final
Pittsburgh Steelers 463 Steelers
+102 -110 N/A -130 -120 -114 +105 N/A -130  
New England Patriots 464 Patriots
-122 -110 N/A even even -104 -140 N/A even  

The Steelers will take on the Patriots in this week's NFL action. Kickoff is set for 1:00 p.m. EDT at Gillette Stadium in Foxborough, Mass. The game will be broadcast live on CBS. Here's everything you need to know about Steelers vs. Patriots odds, the latest NFL spreads, NFL over/unders and more.

The Steelers opened as a -1.5 point favorite over Patriots. The total is set at over/under 44.5 total points scored by both teams combined.

Be sure to check out the latest NFL odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Updated on 12/6/25

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Pittsburgh Steelers vs. New England Patriots Best Bet

There may be some value on the rush attempts prop for Jaylen Warren.

THE BLITZ is projecting him to record 17.67 rush attempts, and the oddsmakers are implying 14.17. The model believes there is a 74% chance he records at least 12.5 rush attempts, so there is value on the over at -130.

Steelers vs. Patriots Best Bet: Jaylen Warren Over 12.5 Rush Attempts

(Pick from Derek Carty)

Looking for more best bets? Check out our free NFL picks and our premium subscription for the best picks!

What Time is the Pittsburgh Steelers vs. New England Patriots Game?

The Pittsburgh Steelers vs. New England Patriots at 1:00 ET on Sunday, September 21st.

Where is the Pittsburgh Steelers vs. New England Patriots Game Being Played?

This game will be played at Gillette Stadium in Foxborough, MA.

How Can I Watch Patriots vs. Steelers?

You can watch Patriots vs. Steelers on CBS.

Can the Patriots Beat the Steelers?

Yes, with a spread as small as 1.5, the Patriots are slated as basically a pick 'em against the Steelers.

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Derek Mountain

Derek Mountain

Derek Mountain works in the Boston area as an SEO Performance Associate for Better Collective. Derek is a recent graduate of the College of the Holy Cross in Worcester, MA where he played football for five years as well as walking on the basketball team his freshman year. Derek has experience writing and editing casino content for nearly four years. More from Derek Mountain
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