Jaguars vs. Saints Predictions, Odds, Preview
Jacksonville Jaguars vs. New Orleans Saints - Predictions
Score Prediction - Jaguars 20, Saints 17
No matter what people think, Trevor Lawrence will be the starting quarterback in Jacksonville when the season begins.
Lawrence should get more reps on Monday at New Orleans as the Jags are flipped from a favorite to underdog this week after losing in Week 1 of the preseason.
The Saints turned the ball over six times last week at Baltimore and surely they will want to fix that, but I'll take the points with Jacksonville on the road.
Jacksonville Jaguars vs. New Orleans Saints - Game Odds
- Jacksonville +4 (-110)
- New Orleans -4 (-110)
- Jacksonville ML (+155)
- New Orleans ML (-190)
- Over 39.5 (-110)
- Under 39.5 (-110)
Odds per BetMGM - Subject to Change

Jameis Winston and the Saints seek their first preseason win against the Jaguars. (AP)
Jacksonville Jaguars vs. New Orleans Saints - Betting Analysis
- Venue: Caesars Superdome
- Location: New Orleans, Louisiana
- TV-Time: ESPN - 8:00 p.m. ET
Jacksonville Jaguars vs. New Orleans Saints - Preseason Review
The Saints have begun the post-Drew Brees era with Jameis Winston looking to take over the reins at quarterback.
The former top pick from Florida State threw for 96 yards, one touchdown, and one interception in a 17-14 defeat at Baltimore last week.
Each New Orleans quarterback (Winston, Taysom Hill, and Ian Book) all threw one interception apiece, while the Saints were outgained on the ground, 149-94.
Jacksonville ushered in the Urban Meyer era with a 23-13 defeat to Cleveland last week as three-point favorites.
Top draft pick Trevor Lawrence completed 6-of-9 passes for 71 yards, but the Jacksonville defense yielded 319 passing yards to Cleveland in the loss.

Preseason History - Head Coaches
(SU-Straight Up, ATS - Against the Spread, OU - Over-Under)
Jacksonville - Urban Meyer
- 0-1 SU, 0-1 ATS, 0-1 O/U
New Orleans - Sean Payton
- 26-28 SU, 27-27 ATS, 23-28-3 O/U
On the Beat
Payton said Jameis Winston is starting this week against Jacksonville.
— Nick Underhill (@nick_underhill) August 21, 2021
Preseason Trends to Watch
*Note - No Preseason Games played in 2020
Jacksonville
- 0-5 SU/ATS last five preseason games
New Orleans
- Under 4-0 last four preseason games
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