Cincinnati Bengals vs. New Orleans Saints Picks, Predictions, Odds

Michael Crosson Sports Betting Expert

3 minute read

Week 6 of the NFL season will resume on Sunday afternoon with a compelling non-conference clash between the Cincinnati Bengals and New Orleans Saints. Coverage begins from Caesars Superdome in New Orleans at 1:00 p.m. ET on CBS.

Updated on 07/03/2025

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CINCINNATI BENGALS vs. NEW ORLEANS SAINTS BETTING PREDICTION

The Bengals stumbled out to an incredibly disappointing start to the season, as Cincinnati opened with a pair of head-scratching losses to Pittsburgh and Dallas, while scoring just 18.5 PPG and turning the ball over five times in those affairs. However, Cincy flipped the script in Week 3, as the Bengals cruised to double-digit victories over the Jets and Dolphins prior to posting a narrow 19-17 loss in Baltimore this past Sunday.

The Saints, on the other hand, have been on quite the rollercoaster to open the season, as New Orleans averaged 33 PPG on 412 YPG and turned the ball over three times in victories over Atlanta and Seattle in Weeks 1 and 5. However, wedged between those two wins, the Saints also posted three straight losses, as the New Orleans scored just 16.3 PPG on 357 YPG and turned the ball over 10 times in consecutive losses to the Bucs, Panthers, and Vikings in Weeks 2 through 4.

The Bengals’ offense has been wishy-washy in their first handful of games, highlighted by Joe Burrow and co. putting up 27+ PTS in two matchups and scoring 20 PTS or less in three of them. However, Cincy’s offense should ultimately have a field day against a Saints’ defense that’s surrendered 20+ PTS in five straight contests to open the season (25.6 PPG).

Score Prediction: Bengals 27, Saints 20
Best Bet: Bengals -2 (-110)

CINCINNATI BENGALS vs. NEW ORLEANS SAINTS BETTING ODDS

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CINCINNATI BENGALS vs. NEW ORLEANS SAINTS BETTING RESOURCES

Date: Sunday, Oct. 16, 2022
Matchup: AFC North vs. NFC South
Venue: Caesars Superdome
Location: New Orleans, Louisiana
Time-TV: CBS, 1:00 p.m. ET

CINCINNATI BENGALS BETTING ANALYSIS

The Bengals stumbled out to an incredibly disappointing start after coming just three points shy of winning last year’s Super Bowl, as the reigning AFC Champs dropped their first two matchups of the season to the Steelers and Cowboys, making Cincinnati just the sixth team in the Super Bowl era to start 0-2 immediately following a trip to the big game.

The Bengals have played decent football since their head-scratching 0-2 start, considering they scored 27 PPG on 351 YPG and turned the ball over just twice across a 2-1 split against the Jets and Dolphins. However, Cincy’s O-line still has tons of work to do, considering Burrow has already taken 18 sacks through Week 5, which is the fourth-worst mark in the league only ahead of the Commanders, Colts, and Rams.

NEW ORLEANS SAINTS BETTING ANALYSIS

The Saints barreled out to a red-hot start with Jameis Winston under center last season, as New Orleans opened with a solid 5-2 run that included tough victories over the Packers, Patriots, and Buccaneers. However, Winston suffered a season-ending knee injury in Week 8, and the Saints went 4-6 the rest of the way.

The Saints are a much different squad in the aftermath of Sean Payton’s retirement, but they still have all the necessary pieces to field a solid team. However, talent-level doesn’t matter if you can’t protect the football, as the Saints turned the ball over a league-high 13 times in their first five contests, and that type of turnover rate is almost always a recipe for disaster.

CINCINNATI BENGALS vs. NEW ORLEANS SAINTS BETTING TRENDS

• The Bengals are 11-2 ATS in their last 13 games.
• The total has gone UNDER in eight of New Orleans' last 12 games.
• The total has gone UNDER in 10 straight Bengals' games.
• The Saints are 2-6 SU in their last eight home games.
• The Bengals are 2-4 SU in their last six games.
• The Bengals are 5-1 ATS in their last six games against New Orleans.
• The Bengals are 4-2 SU in their last six games against New Orleans.
• The total has gone UNDER in eight straight Bengals' road games.
• The Bengals are 4-2 SU in their last six road games against New Orleans.

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• Compare the latest NFL Odds from the best sportsbooks before placing a bet on this week's games.
• Sports betting is live in North Carolina! Check out our list of North Carolina Sportsbooks and get ready for the NFL season.
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Michael Crosson

Michael Crosson began his time at VegasInsider as a freelance NBA writer back in 2019 while he continued to study Psychology and Biology at James Madison University. Following his graduation in 2021, Michael joined the team full-time, and he's been with VI ever since. Michael still writes NBA, NFL, and MLB for VI, as well as gambling industry news. He's also become a crucial part of our editorial production team. More from Michael Crosson