Indiana vs. Oregon: Prediction, Odds, Best Bet

Indiana vs. Oregon: Prediction, Odds, Best Bet

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IU @ ORE Odds

The Indiana Hoosiers will take on the Oregon Ducks in this week's NCAAF action. Kickoff is set for 3:30 p.m. EDT at Autzen Stadium in Eugene, Ore. The game will be broadcast live on CBS. Here's everything you need to know about Indiana vs. Oregon odds, the latest NCAAF spreads, NFL over/unders and more.

The Oregon Ducks opened as a -7.5 point favorite over Indiana. The total is set at over/under 55.5 total points scored by both teams combined.

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Updated on 10/10/25

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Indiana vs. Oregon Best Bet

The Hoosiers have a strength of schedule rank of 70th, drawing attention to their marks of 130th in Rush EPA allowed and 126th in standard downs EPA allowed.

There were busted runs against the Hoosiers to open the season, but they allowed just one rush to go for 20 yards in two games against Iowa and Illinois.

The ultimate test for the Hoosiers will be Oregon's receiving corps of Dakorien Moore and Malik Benson, who are both averaging more than 2.3 yards per route run.

Action Network's Betting Power Ratings call for Oregon to be favored by nine, giving minimal value on the Ducks until the market shifts to a flat -7.

However, there will be an investment on the full-game over and Oregon's team total over.

Indiana should have success in man concepts with Black against the Ducks' defense, but Oregon's inside zone will test the Hoosiers' checkered resume against run explosives.

Indiana vs. Oregon Best Bet: Oregon TT Over 31.5 | Over 55

(Pick from Collin Wilson)

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What Time is the Indiana vs. Oregon Game?

The Indiana Hoosiers will take on the Oregon Ducks at 3:30 ET on Saturday, October 11th.

Where is the Indiana Hoosiers vs. Oregon Ducks Game Being Played?

This game is going to be played at Autzen Stadium in Eugene, OR.

How Can I Watch Indiana vs. Oregon?

You can watch Indiana vs. Oregon on CBS.

Can Indiana Beat Oregon?

Absolutely, the Indiana Hoosiers will try to build out their resume with an impressive win at Eugene this weekend.