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Featured Last Updated Oct 25 2025, 11:07 AM

Missouri vs. Vanderbilt: Prediction, Odds, Best Bet

Dylan Wilkerson
Dylan Wilkerson Sports Betting Expert
8 minute read
Missouri vs. Vanderbilt: Prediction, Odds, Best Bet

Image Credit: John Reed-Imagn Images

MIZ @ VAN Odds

  • Full Game
  • 1H
  • 1Q
  • 2Q
  • 3Q
  • 4Q
  • Spread
  • Total
  • Moneyline
Missouri Tigers 183 Missouri
+1.5 -110 +1.5 -115 + +1.5 -110 + +2.5 -108 + +1.5 -110 + +1.5 -115 + +2.5 -110 + +1.5 -115 + +2.5 -110 +1.5 -117 + +3 -105  
Vanderbilt Commodores 184 Vanderbilt
-1.5 -110 -1.5 -105 + -1.5 -118 + -2.5 -112 + -1.5 -110 + -1.5 -115 + -2.5 -110 + -1.5 -115 + -2.5 -110 -1.5 -107 + -3 -115  
Missouri Tigers 183 Missouri
o51.5 -118 o25.5 -110 + N/A o24.5 -105 + o25.5 -110 + N/A o26.5 -112 + o25.5 -115 + o24.5 -110 o26.5 -114 + o52.5 -108  
Vanderbilt Commodores 184 Vanderbilt
u51.5 -102 u25.5 -110 + N/A u24.5 -115 + u25.5 -110 + N/A u26.5 -110 + u25.5 -115 + u24.5 -110 u26.5 -114 + u52.5 -112  
Missouri Tigers 183 Missouri
+124 +120 + +120 + +120 + +118 + +115 + +120 + N/A N/A +108 + +130  
Vanderbilt Commodores 184 Vanderbilt
-148 -140 + -145 + -142 + -140 + -145 + -150 + N/A N/A -141 + -155  
Missouri Tigers 183 Missouri
+1.5 -110 +0.5 -135 + +0.5 -140 + +0.5 -135 + +0.5 -135 + +0.5 -130 + +1.5 -152 + +0.5 -150 + -0.5 +155 +1.5 -141 + +3 -105  
Vanderbilt Commodores 184 Vanderbilt
-1.5 -110 -0.5 +105 + -0.5 +110 + -0.5 +105 + -0.5 +105 + -0.5 even + -1.5 +120 + -0.5 +115 + +0.5 -220 -1.5 +107 + -3 -115  
Missouri Tigers 183 Missouri
o51.5 -118 o10.5 -110 + N/A o10.5 -105 + o10.5 even + o10.5 +105 + o10.5 +110 + o10.5 -105 + o10.5 -105 o10.5 +106 + o52.5 -108  
Vanderbilt Commodores 184 Vanderbilt
u51.5 -102 u10.5 -120 + N/A u10.5 -125 + u10.5 -130 + u10.5 -135 + u10.5 -135 + u10.5 -125 + u10.5 -125 u10.5 -137 + u52.5 -112  
Missouri Tigers 183 Missouri
+124 +105 + +110 + +114 + even + +125 + +112 + N/A N/A +104 + +130  
Vanderbilt Commodores 184 Vanderbilt
-148 -135 + -140 + -145 + -130 + -160 + -142 + N/A N/A -136 + -155  
Missouri Tigers 183 Missouri
+1.5 -110 N/A N/A +1.5 -125 + +1.5 -115 + N/A N/A N/A N/A N/A +3 -105  
Vanderbilt Commodores 184 Vanderbilt
-1.5 -110 N/A N/A -1.5 +102 + -1.5 -105 + N/A N/A N/A N/A N/A -3 -115  
Missouri Tigers 183 Missouri
o51.5 -118 N/A N/A o27.5 even + o26.5 -110 + N/A N/A o26.5 -120 N/A N/A o52.5 -108  
Vanderbilt Commodores 184 Vanderbilt
u51.5 -102 N/A N/A u27.5 -120 + u26.5 -110 + N/A N/A u26.5 -105 N/A N/A u52.5 -112  
Missouri Tigers 183 Missouri
+124 N/A N/A +114 + N/A N/A N/A N/A N/A N/A +130  
Vanderbilt Commodores 184 Vanderbilt
-148 N/A N/A -135 + N/A N/A N/A N/A N/A N/A -155  
Missouri Tigers 183 Missouri
+1.5 -110 N/A N/A +0.5 -130 + N/A N/A +1.5 -138 + +0.5 -135 N/A N/A +3 -105  
Vanderbilt Commodores 184 Vanderbilt
-1.5 -110 N/A N/A -0.5 even + N/A N/A -1.5 +102 + -0.5 +105 N/A N/A -3 -115  
Missouri Tigers 183 Missouri
o51.5 -118 o14 -110 + N/A o13.5 -135 + N/A N/A o14.5 +102 + o13.5 -130 N/A N/A o52.5 -108  
Vanderbilt Commodores 184 Vanderbilt
u51.5 -102 u14 -110 + N/A u13.5 +105 + N/A N/A u14.5 -128 + u13.5 +105 N/A N/A u52.5 -112  
Missouri Tigers 183 Missouri
+124 +115 + N/A +105 + N/A N/A +114 + N/A N/A N/A +130  
Vanderbilt Commodores 184 Vanderbilt
-148 -135 + N/A -135 + N/A N/A -146 + N/A N/A N/A -155  
Missouri Tigers 183 Missouri
+1.5 -110 N/A N/A +0.5 -145 + N/A N/A +1.5 -166 + +0.5 -155 N/A N/A +3 -105  
Vanderbilt Commodores 184 Vanderbilt
-1.5 -110 N/A N/A -0.5 +114 + N/A N/A -1.5 +122 + -0.5 +120 N/A N/A -3 -115  
Missouri Tigers 183 Missouri
o51.5 -118 o13.5 -110 + N/A o10.5 -110 + N/A N/A o10.5 -102 + o10.5 even N/A N/A o52.5 -108  
Vanderbilt Commodores 184 Vanderbilt
u51.5 -102 u13.5 -110 + N/A u10.5 -120 + N/A N/A u10.5 -122 + u10.5 -130 N/A N/A u52.5 -112  
Missouri Tigers 183 Missouri
+124 +105 + N/A +105 + N/A N/A +108 + N/A N/A N/A +130  
Vanderbilt Commodores 184 Vanderbilt
-148 -125 + N/A -135 + N/A N/A -136 + N/A N/A N/A -155  
Missouri Tigers 183 Missouri
+1.5 -110 +0.5 -140 + N/A -0.5 +114 + N/A N/A +1.5 -160 + +0.5 -150 N/A N/A +3 -105  
Vanderbilt Commodores 184 Vanderbilt
-1.5 -110 -0.5 +120 + N/A +0.5 -145 + N/A N/A -1.5 +124 + -0.5 +120 N/A N/A -3 -115  
Missouri Tigers 183 Missouri
o51.5 -118 o14.5 -110 + N/A o14.5 -105 + N/A N/A o13.5 -118 + o14.5 +115 N/A N/A o52.5 -108  
Vanderbilt Commodores 184 Vanderbilt
u51.5 -102 u14.5 -110 + N/A u14.5 -125 + N/A N/A u13.5 -106 + u14.5 -145 N/A N/A u52.5 -112  
Missouri Tigers 183 Missouri
+124 even + N/A -120 + N/A N/A -100 + N/A N/A N/A +130  
Vanderbilt Commodores 184 Vanderbilt
-148 -120 + N/A -110 + N/A N/A -130 + N/A N/A N/A -155  

The Missouri Tigers will take on the Vanderbilt Commodores in this week's college football action. Kickoff is set for 3:30 p.m. EDT at FirstBank Stadium in Nashville, Tenn. The game will be broadcast live on ESPN. Here's everything you need to know about Missouri vs. Vanderbilt odds, the latest college football spreads, college football over/unders and more.

The Vanderbilt Commodores opened as a -2.5 point favorite over Missouri. The total is set at over/under 51.5 total points scored by both teams combined.

Be sure to check out the latest college football odds and stay up to date on the latest sportsbook promos, including the bet365 bonus code!

Be sure to check out my complete list of college football week 9 best bets.

Updated on 10/25/25

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Missouri vs. Vanderbilt Best Bet

This heavyweight matchup of former SEC East members can be considered a College Football Playoff elimination game.

Missouri will have advantages with Hardy in outside zone usage, as Vanderbilt has been tepid against the run concept.

The Commodores have been most vulnerable against the pass, an area in which the Tigers may have an advantage. Pribula leads an offense that ranks second nationally in passing downs Success Rate, ranking sixth in third-down conversions.

The biggest handicap in this game is the ability to stop Pavia in scripted ground attacks and improvised passing downs. Batoon's 2024 defense struggled to contain Pavia on the ground but hammered the quarterback in passing downs.

There's an argument that this Missouri defense is better suited for Vanderbilt's ground game, as the Tigers are excellent against man run concepts. Counter has been the explosive concept for Vanderbilt, but Missouri allows an explosive on just one of 10 attempts.

With a PFF tackling grade of 19th, don't expect Pavia and Alexander to gain many yards after first contact.

Action Network's betting power ratings make this game a pick'em, giving value to Missouri in the market.

Considering Vanderbilt's struggles in defensive passing downs, the Tigers' ability to stop Vandy's most-used rush concepts will be the difference in this game.

Missouri vs. Vanderbilt Best Bet: Missouri +2.5


PLACE THIS BET INSTANTLY AT FANATICS!

(Pick from Collin Wilson)

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What Time is the Missouri vs. Vanderbilt Game?

The Commodores will take on the Tigers at 3:30 PM ET on Saturday, October 25th.

Where is the Missouri vs. Vanderbilt Game Being Played?

This game is going to be played at FirstBank Stadium in Nashville, Tenn.

How Can I Watch The Vanderbilt vs. MIssouri Game?

You can watch Vanderbilt vs. Missouri on ESPN.

Can Missouri Beat The Vanderbilt Commodores?

Absolutely! Missouri is a slight underdog in this game. Anything can happen in college football!

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Dylan Wilkerson

Dylan Wilkerson

Dylan Wilkerson has over 5 years of experience reporting and analyzing the sports betting industry for various sites. His portfolio includes work for SportsHandle and Action Network, in addition to VegasInsider. His favorite sports are the NFL, College Football, The PGA Tour, the LIV Tour, and Cricket. Dylan has a broad and deep understanding of various sports-related topics. More from Dylan Wilkerson
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