Last Updated Sep 30, 2021, 8:00 PM

Ole Miss Rebels vs. Alabama Crimson Tide Predictions, Odds, Picks

Oct. 2, 2021
Kevin Rogers
VI Betting Expert

A huge battle takes place in Tuscaloosa for bragging rights atop the SEC West on Saturday when Alabama hosts Mississippi.

Not only are there star quarterbacks on each side, but the Crimson Tide look to beat the Rebels for a sixth straight time when the teams hook up at Bryant-Denny Stadium at 3:30 p.m. ET on Saturday.

Score Prediction: Alabama 41, Ole Miss 24

Best Bet: Alabama -14.5

Best Bet: Under 79

Ole Miss Rebels vs. Alabama Crimson Tide Predictions

Although Ole Miss hung around with Alabama last season at home, the Crimson Tide still dropped 63 points and 723 yards in a 15-point win.

Alabama closed as a 24-point favorite last season, but that number has dipped down to 14.5 in this matchup in Tuscaloosa.

The Rebels haven't faced any great competition this season, while playing its first true road game with its only contest away from Oxford coming in the opening win over Louisville in Atlanta.

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Ole Miss Rebels vs. Alabama Crimson Tide Betting Odds

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Ole Miss Rebels vs. Alabama Crimson Tide Betting Resources

  • Matchup: SEC
  • Date: Saturday, October 2, 2021
  • Venue: Bryant-Denny Stadium
  • Location: Tuscaloosa, Alabama
  • TV-Time: CBS - 3:30 p.m. ET

Ole Miss Rebels Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 3-0
  • ATS: 2-0-1
  • O/U: 2-1
  • ATS - Home: 1-0-1
  • ATS - Away: 0-0
  • ATS - Neutral: 1-0

The Rebels have made plenty of strides under head coach Lane Kiffin by coming off a bowl win last season against Indiana, followed up by a 3-0 start in 2021.

Quarterback Matt Corral is currently the Heisman Trophy favorite at +155 (Bet $100 to win $155), as the redshirt junior has thrown nine touchdown passes this season. Corral sliced up Tulane's defense for 335 yards and three touchdowns in a 61-21 blowout as 14-point favorites on September 18.

Last season, Ole Miss and Alabama combined for over 1,000 yards of offense as the Crimson Tide held on for a 63-48 victory in Oxford. Ole Miss covered as 24-point home underdogs, while Corral threw for 365 yards and two touchdowns in the loss.

Alabama Crimson Tide Betting Analysis

Straight Up - SU, Against the Spread - ATS, Over-Under (O/U)

  • SU: 4-0
  • ATS: 2-2
  • O/U: 3-1
  • ATS - Home: 1-1
  • ATS - Away: 0-1
  • ATS - Neutral: 1-0

The top-ranked Crimson Tide continue to roll as Nick Saban's is riding an 18-game winning streak after destroying Southern Miss, 63-14 last Saturday as 45-point favorites.

Alabama has allowed 14 points or less in three of four games this season, while quarterback Bryce Young is right behind Corral as the second favorite for the Heisman. Young has thrown three touchdown passes or more in all four games, including five touchdowns against Southern Miss, while completing 20-of-22 passes.

Inside the Stats - Ole Miss Rebels

  • Record: 3-0
  • VI Ranking: 16
  • Points Scored: 158
  • Points Allowed: 62
  • PS/G: 52.7 (1st)
  • PA/G: 20.7 (50th)

Inside the Stats - Alabama Crimson Tide

  • Record: 4-0
  • VI Ranking: 1
  • Points Scored: 186
  • Points Allowed: 70
  • PS/G: 46.5 (4th)
  • PA/G: 17.5 (27th)

Key Players to Watch

  • MISS: Matt Corral - QB (66/96, 997 yards, 9 TD, 0 INT)
  • MISS: Dontario Drummond - WR (20 catches, 339 yards, 4 TD)
  • BAMA: Bryce Young - QB (88/122, 1,124 yards, 9 TD, 1 INT)
  • BAMA: Jameson Williams - WR (12 catches, 299 yards, 3 TD)


  • MISS: Casey Kelly - TE (Undisclosed-Questionable)
  • MISS: Bralon Brown - WR (Undisclosed-Out)
  • BAMA: Brian Robinson, Jr. - RB (Ribs-Probable)
  • BAMA: Camar Wheaton - RB (Undisclosed-Questionable)
  • BAMA: Christopher Allen - LB (Foot-Out)
  • BAMA: Xavier Williams - WR (Undisclosed-Out)

Ole Miss Rebels vs. Alabama Crimson Tide Betting Conclusion

The Rebels will likely go to a substantial bowl this season, but they still have a ways to go to catch Alabama in the SEC West.

Corral can help out his Heisman argument with a good game on Saturday, but Young can have his coming out party and follow in the footsteps of former Alabama quarterbacks Tua Tagovailoa and Mac Jones.

Ole Miss Rebels vs. Alabama Crimson Tide Betting Trends

  • Ole Miss has covered five of the last seven meetings with Alabama.
  • Ole Miss is 7-3 ATS in the last 10 games in the underdog role.
  • Alabama is 6-3-1 to the Over in the last 10 games overall.
  • Alabama is 8-3 ATS in the last 11 games vs. SEC foes.

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